Liver Disease Average Cost

From 405 quotes ranging from $500 - 6,000

Average Cost


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What is Liver Disease?

Since the symptoms of liver disease are not specific, owners may have difficulty recognizing a potential problem. Any cat who has stopped eating for two to three days or is exhibiting other concerning symptoms should be seen by a veterinarian immediately. Liver disease is serious and can be life-threatening. Early diagnosis and treatment are critical to the likelihood of recovery.

The liver is responsible for many important functions including filtering toxic substances from the blood, digesting nutrients, and storing vitamins and minerals. Its many functions make the liver susceptible to damage, while its ability to regenerate decreases the likelihood that damage will be permanent. Cats with liver disease may experience a neurological syndrome known as hepatic encephalopathy which is indicated by behaviors such as aimless wandering, circling, and head pressing. Loss of appetite and extreme weight loss are also potential signs of the condition. 

Symptoms of Liver Disease in Cats

Symptoms of liver disease will depend on the underlying cause. Affected cats may experience one or more of the following:

  • Decreased appetite
  • Weight loss
  • Jaundice
  • Pale gums
  • Excessive thirst
  • Vomiting
  • Stomach ulcers
  • Diarrhea
  • Excessive urination
  • Dark-colored urine
  • Excessive drooling
  • Muscle Wasting
  • Distended abdomen 
  • Buildup of abdominal fluid
  • Gastrointestinal bleeding
  • Changes in liver size
  • Behavior changes
  • Lethargy
  • Depression 
  • Collapse


Common types of liver diseases include:

  • Hepatic lipidosis
  • Cholangiohepatitis (acute or chronic)
  • Lymphocytic Portal Hepatitis

Causes of Liver Disease in Cats

Hepatic Lipidosis

Hepatic lipidosis, or “fatty liver disease”, is the most common severe liver disease found it cats. It is more likely to occur middle-aged cats and those that are extremely overweight. The condition is connected to malnutrition which may be caused by any of the following factors:

  • Lack of protein or inability to process protein
  • Prolonged Anorexia
  • Stress 
  • Hormonal disturbances
  • Changes in Diet
  • Kidney Disease
  • Diabetes
  • Pancreatitis
  • Cancer


Cholangiohepatitis has been linked to the following conditions:

  • Bacterial, fungal, or protozoal infection
  • Feline infectious peritonitis
  • Feline leukemia
  • Toxoplasmosis
  • Liver flukes

Lymphocytic Portal Hepatitis

Lymphocytic portal hepatitis is thought to be related to an immune or thyroid disorder, though no specific cause has been definitively determined.

Diagnosis of Liver Disease in Cats

The treating veterinarian will begin by reviewing the cat’s medical records and discussing with owners the severity and onset of symptoms. The vet should also be made aware of any preceding events that may have brought about the condition. A standard set of lab tests will be ordered including complete blood count (CBC), biochemistry profile, electrolyte panel, and urinalysis. X-rays or ultrasound may be ordered and a liver biopsy or needle aspiration will be needed to make a definitive diagnosis.

Treatment of Liver Disease in Cats

Treatment recommendations will depend on the underlying cause of the liver disease and the severity of symptoms. 


If the cat is suffering from advanced disease or displaying acute symptoms, intensive in-patient care and treatment will likely be necessary to stabilize it before other treatment methods are considered. Electrolytes imbalances will need to be addressed promptly. The cat is likely to receive fluid therapy and supplements of B-complex vitamins, thiamine, and cobalamin. Abdominal swelling will likely be treated with a needle aspiration or prescribed diuretic. 

Nutritional Support

If the cat is malnourished, the vet may prescribe an appetite stimulant. It is often more likely that the cat will require food to be administered through a syringe or feeding tube. This many need to continue for as long as several weeks until the cat is able to consume sufficient calories on its own.

Prescription Drugs

Depending on the underlying cause, the veterinarian may prescribe antibiotics and/or corticosteroids to address any underlying infection and reduce inflammation. In the case of lymphocytic portal hepatitis, immunosuppressant drugs may also be recommended.

Dietary Changes

Once the cat has been released from the hospital, the focus will be on minimizing stress on the liver by reducing the amount of fats, proteins, carbohydrates, and drugs that must be processed. This can be accomplished in part by feeding a high-quality diet that is high in protein, calorie-dense, easy to swallow, easily digested, and low in sodium. The cat will need to frequently be fed small meals to minimize stress on the system. Ongoing dietary supplements may also be prescribed.

Recovery of Liver Disease in Cats

If an affected cat is able to survive the first few days of treatment, prognosis is generally good and recovery can be expected within three to six weeks. It is important that veterinary recommendations are followed and that dietary restrictions are adhered to closely. Follow-up visits will be necessary to ensure proper recovery.

Efforts should be made to ensure that the cat is not stressed, and it should be given a quiet place to rest and recover away from children and other animals. Owners will need to keep a close eye on the cat’s weight, hydration, and overall health and inform the veterinarian promptly of any changes.

Liver Disease Questions and Advice from Veterinary Professionals

short haired tabby
16 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms

Increased thirst
Weight Loss
No appet
Dark Urine

Medication Used


I have a 16 year old cat and he has hyperthyroidism with symptoms of weight loss, diharrea, increase thirst, behavioral changes, lethargy. His skin also turned yellow because of his liver levels from blood work were abnormal. A couple days ago I had enema done for him because he was very constipated for 2 days. The vet gave him antibiotic injection that lasts two weeks and fluids that I administer everyday. He also takes tapazole, prednisolone, denamarin, cernia, Mirtazapine, and Renal K+ gel because he has low levels of potassium. After he got his colon cleaned out he has been very tired, drinks a lot and even lays by his water fountain bowl, and ocassionally eats treats. He is at the point where he doesn’t want to eat but just drink water. I ended up force feeding him by syringe twice a day less than half a cup of wet watery food Hill’s Y/D to keep his thyroid under control and get some food in him. So finally my question is what are the chances that his liver will recover and he’s appetite kicks in as well as bowl movements and energy? Also he has one small and big kidney but blood work indicated kidney levels were normal regardless of the difference in size. He also has a heart murmur with normal respiratory rate. He weighs right now 7 lbs. He hasn’t gain or lost weight in the past three days after enema procedure.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2492 Recommendations
The problem with liver disease is that there are multiple different causes which may be causing the increase in liver enzymes, these causes include medications like Tapazole (methimazole) as well as conditions like hyperthyroidism. I don’t think the liver enzymes will return to normal under the circumstances but the Denamarin may help reduce the levels. Regards Dr Callum Turner DVM

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5 Years
Critical condition
0 found helpful
Critical condition

Has Symptoms

Weight loss, loss of appetite
Weight loss,

Medication Used

Pain medication, appetite enhancer

We took our cat to the vet after he stopped eating. They diagnosed it as an upper respiratory infection and gave medication for it. He still wasn't eating after a week and they said we should start force feeding. He isn't getting better. What do you think is the best course of action. I think he's in alot of pain. He can hardly move.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2492 Recommendations
Without examining Bear I cannot confirm your Veterinarian’s diagnosis or give a diagnosis myself, a loss of appetite and weight loss is common among hundreds of different conditions; you should try to force feed, I find the best way is to mix smooth wet food and water into a paste and syringe slowly drop by drop onto the tongue to get things moving. If there is no improvement visit your Veterinarian or another Veterinarian for a second opinion. Regards Dr Callum Turner DVM

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9 Years
Critical condition
0 found helpful
Critical condition

Has Symptoms

Yellow Eyes
Loss of Balance
Abdominal Mass
Loss of Appetite

My Cat is 9 years Old,last week she took a small amount of anesthesia for her hair cut the next Day she was given revolution for fleas,the very next day she started to get sick,loss of appetite shivering,i went to a vet where a blood test was taken and found ALT AST is very high ,they started by transferring syline 100 ml through vein plus vitmanis and antibiotic and suggest to force feeding her,a week now no progress at all in her condition she is always not moving not responding to any sounds/moves,the only improvement that she accept syrnge feeding without resistance ,is there hope she can recover?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2492 Recommendations
In the symptoms listed you noted an abdominal mass, but there is no mention of the mass in your question; if the mass is on the liver it may be an explanation of the increased liver values. However, I cannot give you any specific advice since we cannot determine the specific underlying cause but you should ensure that Violla is hydrated. Regards Dr Callum Turner DVM

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Four Years
Moderate condition
1 found helpful
Moderate condition

Has Symptoms

bleeding, lethargy, loss of appetit
Internal bleeding, lethargy

Morris our cat has just returned from emergency vet care for the 4th time in his life. He is only 4. Between each episode he is a lively, bouncey, full of life healthy cat that has a good appetite and energy. You would think a normal, healthy 4 year old. Then sporadically the most devasting thing happens all presenting the same symptoms and he deteriorates very quickly. The first time internal bleeding, low blood count. Transfusion sorted it fairly quickly. 2nd time same symptoms - lethargy, loss of appetite. Pancreatitis was picked up on a test but said not totally reliable later and also never been positive for it since. No internal bleed. Treatment sorted him & since been on a easy digest diet, no grain etc . . 3rd time again same symptoms and low blood count diagnosed. 4th time recently same symptoms, low blood count. Transfusion of own blood not so successful so another cat transfusion carried out. Scans picked up liver disease. Some blood clotting. Vet said cannot determine which form of liver disease & biopsy not possible with blood levels & clotting. Other cat transfusion and Vitamin K seemed to improve him and increase bloods and stop clotting over a few days plus had fluid drip. Began eating on own accord as bloods risen and was back to self in a few days. Told biopsy very dangerous and will not be very useful for treatment considering risk. We now have to manage him at home in fear he can deteriorate again very quickly at any time with no idea why or how to try and prevent it. It has been all reactive care and no proactive. We have had no nutrition or supplement advice but have read that this is so important to prolong the longest healthiest life in cats with liver disease. Hence no idea what is best to feed him on or whether there are certain supplements that could help halt the progression? As we weaned him off commercial run of the mill cat food and selected food that was higher quality, grain free, low fat & highly digestible after the Pancreatitis episode, we are wondering is this ok to continue or more harmful now liver disease has been identified? What diet is best / recommended and what supplements if any may help?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2492 Recommendations
Without examining Morris and checking all patient records etc… I cannot make specific instructions but I can guide you in the right direction. For diet it is important to ensure that you feed a low quantity but high quality protein diet to reduce stress on the liver, this diet should also take into account the pancreatitis and other pre existing medical conditions; since each diet needs to be formulated for each pet in these circumstances it would be best to discuss with a Veterinary Nutritionist about this as they can review Morris’ case and give a recommendation, check the company below as they produce tailor made diets and have a Q&A section on their website specifically for nutritional questions. As for supplements, I would ensure that Morris is at least taking Denamarin (silybin and SAMe) as well as any vitamins or minerals if your Veterinarian feels he is lacking. Regards Dr Callum Turner DVM

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American Shorthair
14 Years
Serious condition
1 found helpful
Serious condition

I went to a terrible vet who did not diagnose my cat with fatty liver. The cat went from 9 lbs to 6 lbs, has jaundice and has completely stopped eating. Vet didn't even explain Hepatic lipidosis as a concern and didn't express urgency in getting calories down immediately. I learned all from google and calling an old vet friend. My cat it taking the food (A/D w/ calorie boost gel + olive oil). He is vomiting about 2-3 hrs after feeding. Is he still getting calories and nutrients to the liver? He is very thin but walks around, jumps on bed to sleep with me, etc. cause of fatty liver is unknown. Vet friend wants to make sure not tumors. In meantime, what the the signs of improvement? I've started B vitamins, curcumin and SAMe. Going to get anti nausea from vet friend to help him. I give fluids subcutaneously- got this from the bad vet I saw and refuse to go back to.

What are he signs he is recovering and receiving enough calories? Is there anything else I should be doing. He gets around 300 cals per day. I force feed- vet friend who I am going to see says he doesn't think feeding tubes are a good idea. I just feel like I'm not getting enough help and I'm scared a new vet will try to put him down.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2492 Recommendations
It is certainly best to get some antiemetics from your friend so that Blue has a better chance of keeping down food, it may be worth feeding in smaller portions to see if that helps (not overloading the stomach at once). Liver support is vital and SAMe is a good start, if you can get some silybin as well it would also help (if you can find Denamarin it would be best as it has both SAMe and silybin). I agree with your friend, I am not a fan of feeding tubes unless absolutely necessary; I would continue as you are doing but try breaking up meals into smaller more regular portions. Regards Dr Callum Turner DVM

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