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- Overproduction of Estrogen in Dogs
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- Lethargy
- Pale gums
- Blood in urine, stool and/or vomit
- Fever
- Infections
- Thinning hair and/or hair loss
- Males exhibiting female characteristics
- Infertility
- Prolonged estrus in females
- Enlarge vulva and/or teats in female
- Bleeding from vulva
- Decreased attraction to opposite sex in intact males
- Increased attraction to opposite sex in females
- Tumor on tail in males
- Testicular mass in males
- Testicular atrophy in males
- Prostatic dysfunctions in males
- Prostatic cysts in males
- Artificial estrogen or testosterone supplementation
- Excessive production of estrogen (idiopathic)
- Ovarian tumor
- Ovarian cysts
- Testicular tumor
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