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- Increased thirst due to the buildup of toxins and waste in the bloodstream (polydipsia)
- Increased urinary output
- Loss of appetite
- Weight loss
- Bloody or cloudy urine
- Vomiting
- Diarrhea
- Bad breath that smells like ammonia
- Oral ulcers on the tongue and gums
- Dry coat
- Constipation
- Brown-colored tongue
- Weakness
- Lethargy
- Indifference
- Acute, which develops within days or weeks
- Chronic, which develops slowly over time due to chronic kidney disease
- Poisons, such as antifreeze, pesticides or cleaning fluids
- Heart failure with low blood pressure that prevents enough blood from flowing to the kidneys
- Trauma from an accident
- Shock from dehydration or rapid blood loss
- Kidney infection
- Urinary tract obstruction
- Congenital and hereditary abnormalities
- Fungal infections
- Bacterial infections
- Repeated urinary infections that wear the kidneys down over time
- Kidney cancer
- Medications, such as acetaminophen
- Autoimmune disorders
- Advanced dental disease
- Thyroid problems
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