What is Mammary Gland Tumor?
Nearly one third of all tumors in cats occur in the mammary, or breast, area of female cats. Mammary gland tumors are typically malignant, meaning cancerous, and rapidly metastasize, or spread to nearby lymph nodes or other areas of your cat’s body. Some studies have shown that over 85 percent of mammary tumors in cats are cancerous, making for a high likelihood that a mammary gland tumor on your cat will be a life-threatening situation. Of these cancerous tumors, the majority are adenocarcinomas, a type of cancer that affects the epithelial cells located under the outer layer of breast tissue. Given the fast rate of growth and spread of these tumors, veterinary care should be sought quickly for the best possible outcome.
Symptoms of Mammary Gland Tumor in Cats
Initially, the mammary gland tumor in your cat will have few, if any, symptoms. It is only as the tumor begins to grow that your cat will experience any pain or discomfort. Things you should watch for include:
- Bumps or masses underneath the skin in the mammary or breast area
- Ulceration, or weeping wound that will not heal, in the breast area
- Lack of appetite as the disease progresses and the cancer spreads to other systems
- Eventually, depression or lethargy as the cancer spreads
Causes of Mammary Gland Tumor in Cats
As with many cancers, the exact cause of mammary gland tumors in cats are unknown. Some of the typical suspected causes of cancer, such as environmental factors or exposure to known carcinogenic chemicals, have not been shown to have a direct correlation with mammary gland tumors. The largest connection to mammary gland tumors has been the presence of sex hormones. Studies have found that cats that have been spayed before a year of age are 86 percent less likely to develop cancerous mammary tumors during their life.
Diagnosis of Mammary Gland Tumor in Cats
Diagnosis of mammary gland tumors in your cat will begin with a thorough physical examination by an experienced veterinarian. Your vet will gently feel the mammary/belly area of your cat to determine the size and location of any mammary gland tumors. Your vet will also gently palpate the lymph nodes located in the mammary area to determine whether they are inflamed. Inflamed lymph nodes in the mammary area could indicate that the cancer has begun to metastasize.
Your veterinarian will also order x-rays for your cat. X-rays will be used to identify the precise location of the tumor and its approximate size. X-rays of the chest and head area can also show if the cancer has begun to spread to other parts of the body, which can help determine which course of treatment would be the most appropriate for your cat. A fine needle biopsy, in which a needle is inserted into the tumor to extract cells, is sometimes used to definitively diagnose cancerous tumors. However, given the high percentage of tumors that are cancerous, your vet may choose to skip this test and proceed straight to treatment.
Treatment of Mammary Gland Tumor in Cats
Treatment of mammary gland tumors in your cats will take one of two forms; surgery or chemotherapy.
Surgery is the preferred method of treatment of mammary gland tumors. Your veterinarian will first perform pre-surgical x-rays in order to determine the approximate size and location of the tumor. This will also allow your vet to determine whether the cancer has spread to the lymph nodes or vital organs. As with any major surgery, your vet will also order a full blood panel to determine if there are any additional underlying conditions that may create additional risk during anesthesia or surgery.
During the surgery, your vet will either remove the tumor or opt to perform a complete mastectomy. Both procedures carry a similar degree of risk and the mastectomy reduces the chance that tumors will regrow or that additional tumors will form. Your vet may also choose to remove the lymph nodes that are located in the mammary area at this time.
The other treatment option for mammary gland tumors is chemotherapy. Chemotherapy is used either alone or in connection with surgical treatment. During chemo, your cat will be prescribed a series of medications administered at regular times. These medications can slow the growth of tumors and can kill any remnant cancer cells or tissue that may not have been operable. Chemotherapy has serious side effects such as lethargy, depression, and lack of appetite. Some of these side effects can be minimized through the use of other medications.
Recovery of Mammary Gland Tumor in Cats
For recovery from surgery, you will need to carefully follow all post-surgical instructions, including follow up visits for suture or staple removal. With either chemotherapy or surgery your vet will recommend regular follow-up exams to ensure that the cancer has not returned or spread.
The prognosis for your cat will often depend on the size of the tumor. Because mammary gland tumors grow and metastasize quickly, the sooner the condition has been identified and treated the lesser the chances are that the cancer has spread to other parts of your cat’s system. In cats treated with surgery and with relatively small tumors, the average life expectancy is increased up to six years. As the tumor size grow, the prognosis for full recovery lessens. In cases of the largest tumors, or when the cancer has begun to metastasize, surgery has been shown to extend life expectancy three to six months.
Mammary Gland Tumor Questions and Advice from Veterinary Professionals
Miss Maisie, my ~13 yo female cat, has been diagnosed with breast cancer. Her age at the time I found her was estimated to be around 4 years. The first thing I did was schedule a vet appointment for a checkup and spaying. The vet called me after the operation to inform me that he did not find anything to remove. To this, I shared that she had been exhibiting heat behavior. He realized that most likely that Miss Maisie had had a previous "fix" which left an ovarian remnant. We first tried hormone therapy to reduce the heat behavior and then decided on another operation to remove the remnant during a time she exhibited heat behavior. All went well. (3rd time is the charm...)
Recently, I discovered "the lump" and called her current vet who advised me to bring her right in. She operated that day (Monday, 4/23/18) and removed the "chain of mammary glands" on the right side. Post-op, she told me that she felt a lymph node on the left side which she said she could remove after we got the pathology report on the tissue she removed. She learned from the path report that she did not "get it all." Miss Maisie has an appointment in a week to get her staples out and an X-ray. I am unsure about getting her operated on again. From the little I have read, it seems that he prognosis for any lengthy survival is poor. Of course, I will ask her vet but would like to hear your opinion. I love my Miss Maisie dearly, and want her to have a good quality of life. I do not want her to suffer.
Thank you for your consideration.
-Mary - Miss Maisie's mom.
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Cat is spaded when <1yo. I palpated a <1cm mass on my cats' breast and had subsequent biopsy that was highly suggestive of cancer, lung x ray clear. My cat underwent a local mastectomy and the mass was dx as tubulopapillary mammary carcinoma. No metastasis to lymph, but there was vascular invasion and extensive necrosis. a small mass without local metastasis makes me hesitant to undergo more surgery, but I am debating asking to undergo a round of chemo to remove any micrometastatic masses since there was vascular involvement. yet, it seems like the nature of the beast is that chemo is not very effective on these disseminated lesions due to their high cell count and hypoxic enviroment.
Since surgery does not provide a cure and the mass was very small, I feel like i am done on that front. But, would you recommend chemotherapy? or even more surgery? I understand the research is poor, but with such a small lesion, I would hate to just provide palliative care when it seems that a more aggressive approach might really work and provide a longer life expectancy.
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My cat is 17 yrs old, just diagnosed with mammory gland tumor. Chest X-ray is clear. No other tumors around area of initial tumor. Cat has diabetes as well. Vet said we could remove tumor. Outcome may not be good. I do not know what to do? Should I have tumor removed?
Thank you for your help.
If your Veterinarian is suggesting surgery, they must believe that Miss Kitty is a suitable candidate for surgery. Surgery is the treatment of choice, but is not suitable for all geriatric cats due to possible liver function issues. Regards Dr Callum Turner DVM
My cat is 19 and also has mammary cancer. I love her dearly but there is no way I would put her through surgery for her to live MAYBE up to 3 more years, because half of that time would be spent doing chemo, recovering etc. Just my opinion but I wouldn't put my cat through all of that. Good luck with your decision, at this point my cat is still eating and doing well, but when I see any suffering I will put her to sleep.
My cat is 7 and has a few oozing bumps and vet said it was cancer. She still moves around and eats good. Vet gave her some pills and a steroid shot. I am not sure if I should do surgery or if that will help. Any thoughts?
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