Benadryl Poisoning Average Cost

From 313 quotes ranging from $200 - 500

Average Cost

$250

First Walk is on Us!

✓ GPS tracked walks
✓ Activity reports
✓ On-demand walkers
Book FREE Walk

Jump to Section

What is Benadryl Poisoning?

Diphenhydramine is a first-generation antihistamine that is frequently used in the brand-name antihistamine known as Benadryl. Benadryl formulated with just diphenhydramine is a human medicine that can be legally prescribed for extra-label uses for canines as well. It is critical that you check the ingredients on the label as some varieties have additional ingredients such as phenylephrine, which can be dangerous to your pet. It is also important to contact your veterinarian to ensure the proper dosage for your pet, as this can vary somewhat depending on your dog’s health history, size, and other medications.

Benadryl is a well-known brand name utilizing diphenhydramine, one of the earliest antihistamines, and it can be prescribed to dogs to relieve the symptoms of allergy.

Book First Walk Free!

Symptoms of Benadryl Poisoning in Dogs

Although Benadryl is generally safe for dogs, some side effects can occur. Side effects usually occur within an hour of administration. They are typically mild and can include:

  • Depression
  • Drooling
  • Excitability
  • Lack of appetite
  • Rapid breathing
  • Rapid heart rate
  • Sedation

Overdoses of Benadryl are more often caused by your animal getting a box of the medication from the garbage or medicine cabinet than by being given too much. If you see these signs of an overdose, contact your veterinarian immediately.

  • Abnormal heart rate
  • Aggression
  • Agitation
  • Difficulty breathing
  • Erratic or aggressive behavior
  • Extreme drowsiness
  • Fever
  • Increased blood pressure
  • Muscle tremors
  • Red eyes

Types

Along with a version of diphenhydramine by the name of Vetadryl developed specifically for cats and dogs, there are a few other first generation antihistamines that can be used for dogs. These can include:

Chlorpheniramine - This antihistamine is frequently used in small animal veterinary practice and is less likely to cause drowsiness than some of the others

Clemastine - Clemastine is classified as an antipruritic (anti-itch), as well as a sedating antihistamine, and is tends to exhibit fewer side effects

Hydroxyzine - This drug is a more aggressive antihistamine, but also has more potent side effects 

Meclizine - Commonly used to reduce nausea, particularly nausea caused by motion sickness

Causes of Benadryl Poisoning in Dogs

Allergies in canines are the defensive mechanism of the immune system which employs specialized immune cells in the dog’s body to defend it against a substance that it sees as an invader. The specialized cells the body uses to protect itself are known as mast cells, and when the immune system is stimulated by allergens, the mast cells release histamine into animal’s system, which has an inflammatory effect on any tissues that it contacts. This results in the dry, itchy, and inflamed skin conditions characteristic of most allergic reactions in canines. Benadryl, when acting as a remedy for allergies, like other first generation antihistamines, blocks the receptors that the histamine would attach to, thereby stopping the reaction to the histamine. However rare, an allergic reaction to the Benadryl itself is possible.

Toxicity resulting from a large ingestion of a product like Benadryl is caused by the overconsumption of ingredients in the antihistamine. Safe under normal circumstances, the overdose of products that cause effects like drowsiness, muscle tremors, and agitation can be dangerous for your pet, leading to poisoning.

Diagnosis of Benadryl Poisoning in Dogs

Unless the consumption of the medication was witnessed, the diagnosis of allergic reaction or poisoning is likely to be driven by the symptoms, and supportive treatments will be started as soon as possible. If you see your dog  ingest a large amount of Benadryl, or he seems to be having a reaction to prescribed Benadryl, gather as much information about the incident as possible and provide the details to the veterinary team upon arrival at the clinic. The age and weight of your dog will be measured, and a urinalysis, complete blood count, and biochemistry profile will also be completed at the veterinarian's office at this time as well. 

Currently, there are no reliable tests that can detect the substance in the blood or urine, so the diagnosis is based on symptomatology and timing. It is helpful to have the packaging on hand. The packaging can help determine the strength of the particular type of Benadryl that your pet consumed, as well as ensuring that toxicity from any additional ingredients is addressed before it becomes a problem.

Treatment of Benadryl Poisoning in Dogs

If you see your dog consume large quantities of Benadryl, but they remain asymptomatic, your veterinarian may instruct you on how to properly induce vomiting. When you reach the veterinarian’s office the treatment of an overdose of Benadryl, or other antihistamines, is mainly supportive. Activated charcoal may be administered to your pet as well in order to soak up as much of the toxin in the stomach as possible and in some cases, a gastric lavage to empty the patient’s stomach, will be initiated. 

IV fluids will most likely be given to prevent dehydration or imbalances in electrolytes, and medications may be given to ease both the tremors and the increased heart rate. It is of particular importance that the temperature is closely monitored so that fevers may be addressed. As overdoses of antihistamines are known to cause a rapid heart rate and increased blood pressure, monitoring the functioning of the cardiovascular system is also critical.

Recovery of Benadryl Poisoning in Dogs

This medication should not be given to dogs with certain disorders as they may exacerbate them. If your pet has any of these disorders, it is important to let the treating veterinarian know before administering any sort of antihistamine. These disorders may include: 

  • Cardiovascular disease
  • Glaucoma
  • Hyperthyroidism
  • Intestinal atony 
  • Liver disease
  • Pregnancy 
  • Prostatic disease 
  • Urinary retention disorders

Benadryl is also known to react negatively with several types of medication. Alert your pet’s doctor if your dog is taking any sort of other drugs. Medications such as tranquilizers, heparin, epinephrine, or barbiturates are known to interact with diphenhydramine, and can be dangerous when taken in conjunction with Benadryl.

Benadryl Poisoning Questions and Advice from Veterinary Professionals

Bosco
Lab mix
11 Years
Serious condition
2 found helpful
Serious condition

Has Symptoms

Dry Patches

Is it ok to give my 60to64lb. 11year old Labmix 3 25mg of Benadryl 3 times a day or 2 25mg 4 times a day? His itchy patches have flared up badly with the warm weather. He has always had trouble with his skin and none of his many tests could ever prove what exactly he is allergic to.Baths help alot.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
With doses of Benadryl (diphenhydramine) you shouldn’t exceed three doses per day; the typical dosage is 1mg/lb up to three times per day however it may be given up to 2mg/lb in severe cases. Therefore, 75mg of Benadryl three times per day should be suitable for Bosco, but if you have any further concerns you should follow up with your Veterinarian. Regards Dr Callum Turner DVM www.msdvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-integumentary-system/antihistamines-for-integumentary-disease

Thank You VERY MUCH for your answer. I was thinking I should not exceed the three times daily and now I feel safer about adjusting the 50mg to 75mg. We started that this morning. I will also follow up with our veterinarian as soon as possible. Thank You again.

Add a comment to Bosco's experience

Was this experience helpful?

Max and Akira
Husky/ pit/ boxer
6 Months
Mild condition
0 found helpful
Mild condition

Has Symptoms

None yet. Just happened

While trying to give our older dog some benadryl both of our puppies stole the cheese we had put the pill in. They are both about 30lbs and it was a whole 25mg pill. Should I be worried? What should I expect as far as side effects? Our older dog is 65 lbs but has never had benadryl before so we only gave him 25mg. He is a year and a half pit mix. Should we give him another pill or wait and see how he reacts first?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Typical dose of Benadryl for dogs is 1mg/lb up to three times per day with a normal therapeutic dosing range of 0.5-2mg/lb so at 30lbs the dose would work out less than 1mg/lb; I would not be concerned at this dosage and them being six months of age. As for your older dog, a since Benadryl tablet would be around 0.5mg/lb which is at the lower end of the therapeutic range, see how he goes but there should be no issues with giving two 25mg tablets two or three times per day. Regards Dr Callum Turner DVM

Add a comment to Max and Akira's experience

Was this experience helpful?

Milly
Lab and pit mix
3 Years
Moderate condition
2 found helpful
Moderate condition

Has Symptoms

Lethargy
Loss of Appetite

I think our dog may have overdosed on Benadryl. What can I do at home to help her? She will not eat but she drinks. She is lathargic. She ate burger and rice yesterday and seemed better. I have her Benadryl last night and today she is sick

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations

Benadryl poisoning is uncommon, normally Benadryl is dosed at 1mg/lb twice per day; some side effects (not overdose) of Benadryl include lethargy and a loss of appetite. Overdose symptoms include abnormal heart rate, vomiting, diarrhoea, seizures, aggression or depression. It would be worth visiting your Veterinarian for an examination and to make sure that Milly is alright as there may be something going on. Regards Dr Callum Turner DVM

Add a comment to Milly's experience

Was this experience helpful?

Astro
Chihuahua
6 Years
Moderate condition
1 found helpful
Moderate condition

Has Symptoms

Shaking Sleepy High Heart Rate

I gave my 3lb chihuahua a 25 mg benedryl for a bee sting on his tongue. Right now he's shaking and sleepy and won't drink. After reading up I know now that the dose was too large for his size. What should I do?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Astro received around four to eight times the recommended dose of Benadryl (depending on the dosage 1mg/lb to 2mg/lb); the symptoms of Benadryl overdose may include lethargy, lethargy, aggression, abnormal heart rate, abnormal blood pressure, vomiting, diarrhea, loss of appetite, seizures and in some cases death. Generally fluid therapy and activated charcoal administration are recommended (inducing vomiting is useful if administration was within the last two hours); since Astros heart rate is up, I would recommend having your Veterinarian check him over to be on the safe side. Regards Dr Callum Turner DVM www.petpoisonhelpline.com/poison/antihistamine/

Add a comment to Astro's experience

Was this experience helpful?

Duke
Rottweiler
12 Weeks
Fair condition
0 found helpful
Fair condition

Has Symptoms

Sleepiness

I accidentally gave him 25 mg of benadryl and he
was 12-13 lbs.is he going to be okay?hes acting fine just seems sleepy.is this something I should be worried about?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
At a weight of 12.5lbs, we can say that 2mg/lb was consumed; whilst typical dosage of Benadryl in dogs is 1mg/lb we do occasionally dose up to 2mg/lb. My concern is the use of Benadryl at a young age; keep an eye on Duke and visit your Veterinarian if there is no improvement. Regards Dr Callum Turner DVM

Add a comment to Duke's experience

Was this experience helpful?

Rocky
Chihuahua
7 Years
Serious condition
1 found helpful
Serious condition

Has Symptoms

Vomiting

worried I just have my dog too much benadryl. He was chewing and scratching so much he was bleeding. I misread the dosage online. I gave him 4ml instead of 4mg. He just vomited, he is eating and drinking still.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Four milliliters would be enough for a dog of ten pounds or of five pounds at a higher dosage (assuming 12.5mg/5ml and a normal dose of 1mg/lb but may be 2mg/lb). I would keep a close eye on Rocky but would advise you visit your Veterinarian if you are concerned or you feel his heart racing. Regards Dr Callum Turner DVM

I gave 25mg to a 22.5 lb dog. He's not showing any signs or symptoms of overdose after 2 hours. So just keep watching him?

Add a comment to Rocky's experience

Was this experience helpful?

Buck
Chiweenie
3 Months
Serious condition
2 found helpful
Serious condition

Has Symptoms

Hyperactivity
Muscle Tremors
Whining
Increased respiratory rate
Increased Heart Rate
Aggression

This morning Bucks right eye was swollen, and we established that it was a bad reaction to a bee sting. My dad, without thinking, gave Buck a 25 mg tablet of benadryl. Buck is only 3 lbs. We noticed his strange behavior about an hour after we gave him the benadryl and induced vomiting, but it already dissolved into his system. We gave him Gatorade and finally got him calm enough to try to go to sleep, but every time he falls asleep he jumps awake and looks around quickly. He has shown some aggression towards my much larger boxer. What else can I do, and is this fatal?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations

We do not have a fatal dose of diphenhydramine (Benadryl) for dogs but the LD50 is suspected to be around 25mg/kg or 12mg/lb. Common symptoms of Benadryl poisoning include severe agitation, lethargy, sedation, aggression, abnormal heart rate, abnormal blood pressure, vomiting, diarrhea, inappetance, seizures, respiratory depression, and even death. Activated charcoal may help as well as ensuring adequate hydration; I would however recommend visiting your Veterinarian immediately or calling the Pet Poison Helpline. Regards Dr Callum Turner DVM
www.petpoisonhelpline.com/poison/antihistamine/

Did Buck make it?

did buck make it?

There are no open vets this late and the closest animal hospital is 2 hours away. I am worried he won't make it through the night.

Did he make it?

Did buck make it?

Add a comment to Buck's experience

Was this experience helpful?

Calvin
Chihuahua
10 Years
Mild condition
1 found helpful
Mild condition

Has Symptoms

Sleepiness

Hi my 4 lbs chi he has been having the worst allergies so I took him to the vet and he said to give him children Benadryl so the only one they had was liquid 12.5mg in bubble gum flavor. I'm worried that it could be poisoning bc of the flavor and it's diphenhydramine hci dye free sugar free and alcohol free.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
As far as I am aware Children's Benadryl Allergy Bubble Gum Flavor doesn’t contain any toxic ingredients to dogs, the sugar substitute is sorbitol which is safe in dogs (unlike xylitol). A dog Calvin’s size would require only 4mg of Benadryl up to three times per day; it may be wise to contact the Pet Poison Helpline for more information. Regards Dr Callum Turner DVM www.petpoisonhelpline.com

Add a comment to Calvin's experience

Was this experience helpful?

Leonidas
pit bull terrier
5 Years
Serious condition
1 found helpful
Serious condition

Has Symptoms

Vomitting
Sleepiness
Rapid Pulse
Weakness
Diarrhea
Vomiting

My 5 year old pit bull, 70 lbs spent the weekend at a kennel. I picked him up late yesterday. He was active and playful but once we got home was have very bad smelling gas and whispering in his sleep. This morning around 3am he threw up many times and had severe diarrhea. This morning he is the same, a few more diarrhea episodes, looks weak and has a heartbeat of 165-170 from what I can calculate, may be doing it wrong though. When I called the kennel they said they did give him benadryl but couldn't tell me how much since their employees work in shifts. Could this be benadryl related? I heard once them telling a customer they also use claritin. Could that be bad if thats what they gave him?? Could the side effects be this delayed??

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
A heart rate of 170 is almost three beats per second which can be difficult to count if you’re not used to it, remember that if you are listening to the heart there is a lub-dub which one beat; resting heart rate is 70-120 per minute with larger dogs being towards the lower end of the scale. Benadryl should be dosed at 1mg/lb up to three times per day, for a dog Leonidas size would mean three 25mg tablets three times per day; overdose may occur if dosing was excessive, but why was he given Benadryl? What was the primary cause? This is what you need to know; I would recommend you visit your Veterinarian to be on the safe side. Regards Dr Callum Turner DVM

Add a comment to Leonidas's experience

Was this experience helpful?

Dash
Beagle
3 Years
Fair condition
1 found helpful
Fair condition

Has Symptoms

Nasal inflammation
Chronic Rhinitis
Reverse sneezing
Sneezing

My dog is supposed to take Chlorpheniramine 4mg 3x a day. He is about 30-35 lbs I know the normal recommendation is every 8-12 hours. If I can't give exactly every 8 hours is it safe if I give a dosage every 7 hrs twice a day and the last dosage within 10 hrs ? He is also taking azithromycin once day every other day.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
It would be safe as there is a wide therapeutic margin (plus you’re only giving 4mg), every eight hours is just 24 hours divided by three times per day; however you shouldn’t reduce the interval past seven hours. Regards Dr Callum Turner DVM

Add a comment to Dash's experience

Was this experience helpful?

Lucky
Pug Mix
7 Years
Fair condition
1 found helpful
Fair condition

Has Symptoms

Convulsing without regurgitating.

Medication Used

Insulin
benadryl

My diabetic dog had an allergic reaction to something on Tuesday (today is Friday). The vet gave him a Benadryl and Epinepherine shot, and advised me to give him Benadryl every 8 hours which is what I've been doing. If I don't stay on that schedule welts pop back up (even as soon as 6 hours after administration). My concern is this morning (approx 6.5 hours after his last dose) he started convulsing like he was going to throw up but nothing came out. He ate his food, I gave him more Benadryl and his insulin and he was fine. A few minutes ago (approx 7.5 hours after last dose) he started convulsing again right before I was going to give him his next dose. Is this a reaction to the Benadryl or possibly related to the hives? My vet is closed until Monday. Thank you for any help or advice you can give.

Dr. Michele King, DVM
Dr. Michele King, DVM
1604 Recommendations
Thank you for your email. I'm sorry that is happening to Lucky. Without examining him, I'm not sure what might be happening when he is convulsing, but allergic reactions can manifest with GI signs, and since it seems the reaction is continuing to happen, it would probably be best to have him seen at your closest 24 hour clinic. If you call your veterinary clinic and they are closed, they should have a phone number with information on where to be seen when they are closed. I hope that he is okay!

Add a comment to Lucky's experience

Was this experience helpful?

Sonny
Cocker Spaniel
8 Years
Moderate condition
1 found helpful
Moderate condition

Has Symptoms

Panting

I gave my 46 lb cocker 125 miligrams of benadryl. 50 mlg this morning and 75 tonight. His eye balls are rex and he was panting heavily. He is sleeping now, however.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
A dog Sonny’s size should receive around 1mg/lb up to three times per day; he didn’t exceed his daily limit but may be a bit off; if you are noticing symptoms of overdose or toxicity (listed on this page) you should visit your Veterinarian to give him a once over to be on the safe side. Regards Dr Callum Turner DVM

Add a comment to Sonny's experience

Was this experience helpful?

Mya
Chihuahua
2 Years
Fair condition
1 found helpful
Fair condition

Has Symptoms

Sleepiness

My dog has allergies and her scratching woke us both up. Not thinking straight I gave her a whole pill instead of half. She's 14.5 pounds. What should I expect or do?

Dr. Michele King, DVM
Dr. Michele King, DVM
1604 Recommendations
I'm not sure what strength Benadryl Mya got, so it is hard for me to comment on her dosing. Benadryl is a fairly safe anti-histamine, and typically a higher dosage will result in sedation and sleeping. If you are not sure, it would be best to call your veterinarian and let them know what happened.

Add a comment to Mya's experience

Was this experience helpful?

Dover
Shepherd
12 Days
Mild condition
3 found helpful
Mild condition

I have a 12yr old shepard/lab mix that weighs about 8olbs and has skin allergies. I gave her 3 tabs of benedryl last night at 9pm again at 6am and then again tonight at 9pm. I have also been putting hydrocortisone cream on the hotspots. She is now drinking an excessive amount of water. No other symptoms yet is this normal.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
An increase in thirst is more consistent with licking hydrocortisone cream than the Benadryl; try to make sure she cannot lick herself by placing a cone on her or watching her closely. Just keep a close eye on her and make sure that she is recovering, if she still has issues with an excessive thirst or develops other symptoms, visit your Veterinarian. Regards Dr Callum Turner DVM www.petpoisonhelpline.com/poison/corticosteroids/

THANK YOU VERY MUCH!!! :0)

Add a comment to Dover's experience

Was this experience helpful?

Sadie
Border Terrier
2 Years
Mild condition
0 found helpful
Mild condition

Has Symptoms

Thirsty

My dog is 15 pounds and had a liquid gel of 25mg benadryl( not sure if even all 25mg was leaked out into her food) and ate the whole bowl of food with it. She is looking like she is hallucinating almost. I read now it’s only 1mg per pound. I have never given her this before is this normal? Has she been poisoned? She is drinking a lot of water also. Just walking around really slow and out of it. I’m just scared she had too much.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Benadryl may be dosed at 0.5-2mg/lb, but we normally stick with 1mg/lb; however in the liqui-gels there are other ingredients apart from the active ingredient including gelatin, glycerin, polyethylene glycol, purified water and sorbitol which shouldn’t be alarming. However, if Sadie is developing symptoms you should visit your Veterinarian to be on the safe side if she is presenting with symptoms. Regards Dr Callum Turner DVM www.benadryl.com/products/benadryl-allergy-dye-free-liquigels#ingredients

Add a comment to Sadie's experience

Was this experience helpful?

Gypsy
Terrier mix
4 Years
Fair condition
0 found helpful
Fair condition

Has Symptoms

No symptoms yet,

My 18 pound terrier mix ate our other dogs' zyrtec and benadryl while I was preparing their food. She ate a total of 3 25 mg benadryl and 2 10 mg zyrtec. Is there anything I should do for her? I will obviously be watching her for symptoms or problems.

Thank you

Dr. Michele King, DVM
Dr. Michele King, DVM
1604 Recommendations
Those medications have a low toxicity for dogs, and will probably make Gypsy very sleepy. If she is not rousable, she may need IV fluids and hospitalization to monitor her until she is less sedated, but she may just be sleepier than normal.

Add a comment to Gypsy's experience

Was this experience helpful?

Violet
Mini labradoodle
15 Weeks
Critical condition
1 found helpful
Critical condition

Has Symptoms

shock

If my dog had a severe allergic reaction to a distemper vaccine (where she coded and had to be revived) is she at risk for a reaction to medications like Benadryl?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
I wouldn’t advise giving Benadryl to Violet unless it is recommended under the guidance of your Veterinarian especially given Violet’s young age. Benadryl (diphenhydramine) can cause cardiac disturbance at higher doses but should be used with caution in cases like these and only under direction of your Veterinarian. Regards Dr Callum Turner DVM

Add a comment to Violet's experience

Was this experience helpful?

Kip
Mix
Two Years
Mild condition
0 found helpful
Mild condition

Has Symptoms

Tired

I recently adopted a dog and he weighs 34 pounds and is a lab/cocker spaniel mix. He has been having adjustment issues (understandably so) and gets very agitated when my boyfriend and I leave for work. It was recommended to give him one tabled (25mg) in the morning, and then one on my lunch break to calm him down while we are away. There was about a six hour time frame between both of the pills. Is this a safe dosage? He seemed fine when I went home on lunch. I'm just nervous about the second pill since I am unable to be there to watch him.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Benadryl is not approved for use in dogs (or cats) in any country as far as I am aware, however it is used widely in veterinary medicine with the published doses being between 0.5-2mg/lb every eight to twelve hours; typical dosage is 1mg/lb three times per day, so Kip is getting a dose at the low range of the therapeutic window. Regards Dr Callum Turner DVM

Add a comment to Kip's experience

Was this experience helpful?

Magneto
pit bull lab mix
1 Year
Mild condition
1 found helpful
Mild condition

Has Symptoms

Aggression
Excitability
Burping

Medication Used

Diphenhydramine

I walked away for a few minutes and when I came back, he'd chewed through the bottle. He eats fast, so I'm not sure how many he ate. I'm thinking a dozen. They're 25 mg. and he's usually only supposed to have four pills. Symptoms include digesting sounds, burping, aggression and excitability. Is this fatal? Should I induce vomiting and, if so, what's a safe way to do that?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Benadryl poisoning may lead to death in severe cases; if a large quantity of Benadryl has been consumed by Magneto you should take him into your Veterinarian immediately for an examination and gastric lavage if your Veterinarian sees it as appropriate. Gastrointestinal upset, excitability, abnormal heart rate, irregular breathing and other symptoms listed on this page are commonly found. Given the quantity consumed you should go immediately to your Veterinarian. Regards Dr Callum Turner DVM

Add a comment to Magneto's experience

Was this experience helpful?

Louie
Bichon Frise
11 Years
Serious condition
1 found helpful
Serious condition

Has Symptoms

Drowsiness

My girlfriend gave my Bichon a 25 mg. benadryl with his dinner about 30 minutes ago. I just home and fed him again and gave him another one about 30 minutes later not knowing she had already given him one. What should I expect? What should I do?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
A total dose of 50mg of Benadryl for a dog the size of a Bichon Frise is certainly an overdose; I don’t have any specific toxicology information for Benadryl since it isn’t an approved medicine for dogs. You should call the Pet Poison Helpline or visit your Veterinarian for more information. Regards Dr Callum Turner DVM www.petpoisonhelpline.com/poison/antihistamine/

Add a comment to Louie's experience

Was this experience helpful?

Lyle
Terrier mix
7 Years
Fair condition
1 found helpful
Fair condition

Has Symptoms

None yet

I accidentally gave my 13 pound dog my 50 pound dogs dose of Benadryl within minutes ago. He hasn't had any for over twenty four hours till now. It happened moments ago and he seems fine. I have a 90 year old mom to take care of and it is difficult to run him off to vet. What can I do?

Dr. Michele King, DVM
Dr. Michele King, DVM
1604 Recommendations
Thank you for your question. I'm not sure what dosage of Benadryl that you give your 50 pound dog, so can't say for sure if everything will be okay with Lyle. If you give your 50 pound dog 50 mg of Benadryl, and if it is ONLY Benadryl with no other ingedients in it, Lyle may just be very sleepy, or may have some of the following signs: Drooling. Excitability. Drowsiness. Rapid breathing. Rapid heart rate. Depression. If your dogs benadryl had other ingredients in it, or if Lyle starts showing any other signs, he needs to be seen by your veterinarian. The other alternative is to take him now to your veterinarian and have them induce vomiting so that the drug isn't in his system, and they can give him medication to absorb any of the drug that may have already started to get into his system.

Add a comment to Lyle's experience

Was this experience helpful?

Pixel
Chihuahua
6 Months
Fair condition
3 found helpful
Fair condition

HI, I think my 6 pound chihuahua ate 25mg of Benadryl. Last night I was trying to open the bottle and felt like a pill fell on the floor. Then 30 mins ago saw my dow chewing something on that same corner. What should I look after to know if he is reacting to the Benadryl? He is only 6 months. Help!

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Benadryl is normally dosed in dogs at 1mg/lb up to three times per day, but may be dosed at 2mg/lb three times per day meaning at if a six pound dog ate a 25mg tablet he would have received around 4mg/lb which is less than a days dose for a dog Pixel’s size. I would keep a close eye on Pixel since the ingestion was a while ago and if you notice any symptom on this page you should visit your Veterinarian for an examination. Regards Dr Callum Turner DVM

Was Pixel ok?

Add a comment to Pixel's experience

Was this experience helpful?

Bernie
Saint Bernard
7 Years
Moderate condition
1 found helpful
Moderate condition

Has Symptoms

Itching, Irritated Skin, Panting,

My dog weighs 120. Giving her Benadryl for allergies. She's never had it before.
4 pills seems like a lot. Is that safe as a dosage? I would love for her to get some relief but I'm not sure this will remedy.

She's never had allergies before. But the grass in our yard may be bothering her????

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Benadryl is dosed at 1mg/lb (2mg/lb in severe cases) which is a higher dose than in humans as dogs are more tolerant to the medication; therefore a 120lb dog could have four to five 25mg tablets two to three times daily, if you have any concerns you should speak with your Veterinarian. Regards Dr Callum Turner DVM

Add a comment to Bernie's experience

Was this experience helpful?

Jochamo
Aussie/border collie mix
12 Years
Mild condition
2 found helpful
Mild condition

Has Symptoms

Panting and whining

Medication Used

100mg tramadol BID

My dog is a 12 year old Aussie/border collie mix. He was diagnosed with degenerative myelopathy earlier this year. Has a history of food and environmental allergies. He is about 83 lbs. given 75mg of regular benadryl twice a day along w 100mg of tramadol twice a day for his sore back. He accidentally was given 100mg of benadryl this morning. Did not want to come inside even with coaxing. He finally did. Starting to pant and whine for about 15 minutes. Now he's laying down quietly. Is he experiencing an overdose? We have an appointment w our vet today at 5pm for something else. Do I need to take him to the emergency vet before his appointment?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations

Benadryl is quite safe for dogs and is even given at doses of 2mg/lb in severe cases; if Benadryl is the cause, the effects will usually pass. It would be best to have your Veterinarian check Jochamo over to be on the safe side; if you have concerns before hand call the Pet Poison Helpline. Regards Dr Callum Turner DVM
www.petpoisonhelpline.com/poison/antihistamine/

Add a comment to Jochamo's experience

Was this experience helpful?

Cali
Beagle
14 Years
Serious condition
1 found helpful
Serious condition

Has Symptoms

Struggle urinating.

My dog is experiencing urine retention. She has been taking a daily dose of Benadryl for several years. I read that urine retention is a long term side effect. If I stop giving her the Benadryl, will she get back to normal? Is this reversible?
She has been to a vet this week and has a catheter. I decided to do some research on Benadryl this evening. I won’t be able to contact my vet until Monday which is why I am contacting you.

Dr. Michele King, DVM
Dr. Michele King, DVM
1604 Recommendations
Thank you for your question. While that is an uncommon side effect of Benadryl, it does happen, in dogs and in people. As the drug wears off, the urine retention should resolve,yes. If that is the cause of her urine retention, it should improve. Without examining her or knowing more about her case, I am not sure that that is the cause, but it is worth being aware of, for sure. I hope that everything goes okay with her!

Add a comment to Cali's experience

Was this experience helpful?

Portia
Miniature Schnauzer
10 Years
Serious condition
1 found helpful
Serious condition

Has Symptoms

Lethargic
No appetite
Vomiting
Diarrhea
Hives
Shaking

Medication Used

steroid shot
Pepto Bismol
Benedryl

What should I do now?
I'm worried that my dog, Portia. She is having a reaction to the Benadryl we administered to her on Wednesday. She was given Liquid dye-free Pediatric Benadryl dosed at 2.5 mL at 7a.m. on Wednesday morning. She seemed fine. Then my husband gave her another dose at 5:30pm of the Benadryl capsule which was 25 mg. We are aware that we gave to much now, after speaking to the Veterinarian Assistant over the phone. Yesterday (Thursday) morning she had her first symptoms and they progressed as the day went on. She demonstrated symptoms that included: lethargy, loss of appetite, later in the day vomiting, diarrhea, and then her skin was beat red and hot to the touch. I called the Veterinarian again and they said that if she had made it 24 hours then she probably in the clear. Then today she has hives all over and still hot to touch and lethargic. She is drinking water and gatorade now though. She is not moving any more than she has too. Her hives are huge. I took her to the Veterinarian at 11:00 a.m for an examination and to make sure that she was going to truly be okay. He felt that she had contact dermatitis or she had eaten something that she shouldn't have. He gave her a steroid shot for the hives. Said to feed her boiled meat and rice. He said it's not the Benadryl, and wanted us to continue to give it to her a liquid dose twice a day that would be equivalent to a 20 lb child. Her hives are possibly worse this evening. It's 5pm now.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations

Whilst overdosing on any drug is a concern, it seems that Portia didn’t consume a large amount of Benadryl as there are some instances where slightly higher doses are given; the dosage would be dependent on Portia’s weight. The normal dosage of Benadryl in dogs is 1mg/lb body weight whereas the normal dosage of Benadryl for children is 0.5mg/lb (every six hours or so); this means that the normal dose for a 20lb child would be the normal dose for a 10lb dog, different animals require different dosage per pound as each animal (including humans) work slightly differently (also why some drugs are safe in some animals and lethal in others). I do not think it is the Benadryl, but if the hives continue it may be worth getting a second opinion from another Veterinarian. Regards Dr Callum Turner DVM

Add a comment to Portia's experience

Was this experience helpful?

Pippi
King Charles Spaniel
4 Years
Serious condition
1 found helpful
Serious condition

Has Symptoms

Overactive

Went to the vet because my dog's mouth and snout area was swollen. Went to vet, she said that my dog probably ate a bug or got stung. She prescribed 25mg of benadryl 3 times every 6 hours. My dog weighs 23lbs. I gave her the first 25mg tablet and she was sort of loopy, but the swelling went down. I only gave her half a tablet for the second dose. Now, 3-4 hours after the second dose, my dog is over excitable, and has a rapid heart rate. Is she okay?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
Benadryl may be given to dogs at a dose of 1mg/lb up to three times within 24 hours (25mg is fine for a 23lb dog); even at this dose, some dogs may show side effects which may include depression, excitability, rapid heart rate among other effects. If you are noticing these side effects it is important to stop giving Benadryl and visit your Veterinarian for a check to determine whether supportive and symptomatic therapy is required (case by case basis). Your Veterinarian may also suggest an alternative to Benadryl after checking Pippi over. Regards Dr Callum Turner DVM

Add a comment to Pippi's experience

Was this experience helpful?

Shakespeare
Bichon Frise
13 Years
Mild condition
2 found helpful
Mild condition

Has Symptoms

Vomiting

I gave benadryl 25 mg to mu dog he is 24 pounds, after 4 days that I gave him I discontinue and he throw up twice, One week after I gave again benadryl only one dosage of 25mg after 24 hrs he show symptoms of nausea and reflux, do you think benadryl can cause this symptoms??

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3314 Recommendations
It is possible that Shakespeare is sensitive to Benadryl, if he is having trouble with allergies you could try him on cetirizine (Zyrtec) at 0.5mg/lb twice per day to see if there is any difference. If the vomiting continues, visit your Veterinarian to review is condition and treatment. Regards Dr Callum Turner DVM

Didnshakespeare stop eating as well? I had similar experience with my husky and she hasn’t vomited in 24 hours but hasn’t eaten either. I was able to get her to eat turkey lunch meat. Worried cause she turned her nose up at many kinds of kibble, peanut butter and her frozen raw meat (instinct)

Add a comment to Shakespeare's experience

Was this experience helpful?