Excess Protein in the Urine in Dogs
Written By hannah hollinger
Published: 11/10/2015Updated: 11/19/2021
Veterinary reviewed by Michele K.
Excess Protein in the Urine in Dogs - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Excess Protein in the Urine?
Excess protein in the urine can occur in dogs of any age, gender or breed. Because there are several possible causes, it is important for you to obtain a diagnosis for your dog’s excess urinary protein level as soon as possible in order to seek prompt treatment. Sometimes you may notice symptoms and bring your dog in for veterinary treatment in order to obtain a diagnosis; however, sometimes an elevated protein level is only found during urinalysis at a regular health check-up. This is indicative of the importance of bringing your dog in for regular veterinary check-ups even when she does not exhibit any health issues.
Proteinuria is the presence of protein in dog’s urine. Dog’s urine normally contains a trace amount of protein in the urine, as proteins are blocked by the glomerulus, the part of the kidney that filters waste products, or pass through the glomerulus and then reabsorbed by renal tubes or broken down by the epithelial cells of the renal tubes. Proteinuria may be associated with lower urinary tract disease, reproductive tract disease, or an indication of renal dysfunction or damage.
Youtube Play
Excess Protein in the Urine Average Cost
From 16 quotes ranging from $500 - $3,000
Average Cost
$1,200
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Symptoms of Excess Protein in the Urine in Dogs
Excess protein in the urine is a symptom of an underlying cause. Additional symptoms that accompany excess protein in the urine depend upon the cause, as discussed below.
Causes of Excess Protein in the Urine in Dogs
Urinary Tract Infection
  • Strain during urination
  • Inability to urinate
  • Bloody or cloudy urine
  • Fever
  • Loss of bladder control
  • Increased amount and/or frequency of urination
  • Pain during urination
  • Lethargy
  • Vomiting
  • Licking urinary opening
  • Changes in appetite
  • Weight loss
  • Increased thirst
High Blood Pressure
  • Blood in the urine
  • Abnormal eye movements
  • Dilated pupils
  • Retinal detachment
  • Ocular hemorrhage
  • Acute onset blindness
  • Nosebleeds
  • Seizures
  • Disorientation
  • Ataxia, or lack of coordination
  • Circling
  • Partial paralysis of limbs
  • Heart murmurs
Glomerular Disease historically has been found to lead to chronic kidney disease, the symptoms of which are:
  • Loss of appetite, or anorexia
  • Lethargy and weakness
  • Vomiting
  • Increased thirst
  • Increased urination
Diagnosis of Excess Protein in the Urine in Dogs
As with most appointments, the doctor will conduct a thorough physical examination of your dog and ask that you report the onset and extent of any symptoms, as well as any medical history. The most important diagnostic tool will be a urinalysis in order to confirm the presence of elevated protein in your dog’s urine. This test will also include sediment examination in order to identify the presence of any crystals or stones. The urine may be cultured in order to identify specific bacteria that may be causing infection if urinary tract infection is a suspected cause. The concentration of your dog’s urine will be measured, and can indicate the kidney’s ability or inability to correctly process urine, which may indicate kidney failure.
A blood sample will also be analyzed for a chemical blood profile, which will measure electrolyte levels in your dog’s blood as well as elevated levels of creatinine and blood urea nitrogen, all of which will point to chronic kidney disease caused by the glomerular disease. Your dog’s blood pressure may be measured via an inflatable cuff to determine if he is suffering from hypertension. A complete blood count will also be taken in order to measure red and white blood cell and platelet counts and may indicate anemia, another indicator of kidney disease.
Further, x-ray and ultrasound imaging can be utilized in order to observe the size and shape of your dog’s kidney, if kidney failure is suspected. A kidney biopsy may be necessary in the case of glomerular disease causing kidney failure.
Treatment of Excess Protein in the Urine in Dogs
Specific treatment will depend upon your dog’s diagnosis. In severe cases, your dog may need to undergo stabilization treatment for dehydration, which will consist of IV fluids and medications.  Glomerular disease will be treated through a combination of medications and prescription diets.  In the case of inflamed kidneys and urinary tract infections, antibiotics will likely be prescribed. High blood pressure is often treated through a calcium channel blocker or beta-blocker and the possibly the recommendation of a low-sodium diet.
Petted logo

Worried about the cost of treating your pet's symptoms?

Pet Insurance covers the cost of many common pet health conditions. Prepare for the unexpected by getting a quote from top pet insurance providers.

Get a quote

background
Recovery of Excess Protein in the Urine in Dogs
For all treatment, monitor your dog’s recovery process and report any changes in health to your veterinarian right away. You will likely need to schedule follow-up appointments to evaluate the efficacy of your dog’s treatment plan and avoid any complications.
If your dog has been prescribed, or is supposed to be on home cooked special diet, she may display disinterest in the new food as it will not be as flavorful as what she is used to. Consult the veterinarian on how best to address this, as you may be able to enhance the flavor with tuna juice or another liquid.
All recovery of proteinuria regardless of the cause will require sufficient hydration, so be sure to always keep fresh water available and encourage your dog to drink.
Paying to treat proteinuria out of pocket can be a major financial burden. Fortunately, most pet insurance companies reimburse claims within 3 days, putting 90% of the bill back in your pocket. In the market for pet insurance? Compare leading pet insurance companies to find the right plan for your pet.
Excess Protein in the Urine Average Cost
From 16 quotes ranging from $500 - $3,000
Average Cost
$1,200
arrow-up-icon
Top
Excess Protein in the Urine Questions and Advice from Veterinary Professionals
dog-breed-icon
Boxer
dog-name-icon
Bruno
dog-age-icon
2 Years
thumbs-up-icon

1 found this helpful

thumbs-up-icon

1 found this helpful

My pet has the following symptoms:
Incontinence
Hi. We have a 2 year old boxer who has excess protein in his urine. The vet has diagnosed him with Kidney failure, but he is showing no signs of kidney disease. He does not drink excessively, he has not lost his appetite and he is not lethargic. Could it be possible that he has bladder stones and that would cause the excess protein in his urine. The urine also sat in a tube for about 8 hours before being tested. His blood work shows his white count elevated
June 4, 2018

Answered by Dr. Michele K. DVM
1 Recommendations
Protein in the urine can be caused by infection, bladder stones, or inflammation anywhere in the urinary tract. Without additional elevations in kidney enzymes, it isn't possible to diagnose kidney failure from that one lab test. It may be a good idea to either ask for further clarification from your veterinarian, or seek a second opinion to determine what might be going on with Bruno.
June 5, 2018
The reason they gave that diagnosis they say is because he is showing signs of continence. He sometimes dribbles urine but not often. They said the blood work showed elevated white blood count, and his protein count in the blood was over 4.0. They now want to start him on a blood pressure pill but I'm not certain that needs to happen
June 5, 2018
Lisa E.
Was this question and answer helpful?
dog-breed-icon
English Bulldog
dog-name-icon
Ignatius
dog-age-icon
3 Years
thumbs-up-icon

2 found this helpful

thumbs-up-icon

2 found this helpful

My pet has the following symptoms:
None
Hello, my 3 yr old English Bulldog recently had a urinalysis. Everything was normal except his protein was 1+. In February, he had crystals in his urine (his Ph was alkaline) and his protein was 2+. In March, after being tested, everything was in the normal range. Could it be diet? he eats FROMM weight management with some cooked chicken. he also snacks on peppers, celery, green beans carrots and the occasional blueberries.
May 29, 2018
2 Recommendations
There are a few possible causes for some protein to be detected in urine, one of the possible causes is using a non-sterile collection container or contamination of the urine before testing; other causes may include infections, urinary stones, kidney failure, poisoning, hormonal conditions among other causes. Another urine test would be a good idea along with a blood test to be on the safe side. Regards Dr Callum Turner DVM
May 30, 2018
Was this question and answer helpful?
dog-breed-icon
Border Collie
dog-name-icon
Bella
dog-age-icon
24 Months
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Urine Marking
Hi this is the second urine test I had on my dog comes back plus one high for protein all her blood work is excellent she’s on original Orijen dog food which is 38% protein is this normal her blood work is excellent thank you
April 16, 2018
Answered by Dr. Michele K. DVM
0 Recommendations
Without knowing more about Bella, her signs and physical condition, I can't comment on the protein in her urine, unfortunately. Adult dogs typically need about 18-25% protein in their diet, so it may be that that higher protein dog food is causing the excess protein in her urine. If she is showing signs of urinary problems, she may need follow up testing, or you could change her food to a normal protein diet and recheck her urine protein in a few weeks. Your veterinarian will be able to advise you on the right course of action for her.
April 17, 2018
Was this question and answer helpful?
dog-breed-icon
pitbull
dog-name-icon
Roxy
dog-age-icon
3 Years
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Protein (3+)
Hello. My dog unfortantly got a hold of dry cat food while I was at work. She was already scheduled for a checkup at the vet. They did a urine test and found a larger amount of protein. Could this have been caused by the cat food? She has no other symptoms and is eating and drinking normally. She has always had slight stomach issues since adopting her which is why she is on a stricter diet.
March 19, 2018
Answered by Dr. Michele K. DVM
0 Recommendations
Thank you for your email. Urine chemistries can be affected by diet, although it usually pH that is affected. Since she did eat the cat food right before her visit, it might be a good idea to recheck her urine in 2 weeks, just to see if the protein is still there, or if it was related to the sudden diet change. If it is persistent, it would be a good idea to have further diagnostics performed to assess her kidney function. I hope that all goes well for her!
March 19, 2018
Was this question and answer helpful?
Excess Protein in the Urine Average Cost
From 16 quotes ranging from $500 - $3,000
Average Cost
$1,200
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Need pet insurance?
Need pet insurance?

Learn more in the Wag! app

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install


© 2025 Wag Labs, Inc. All rights reserved.


© 2025 Wag Labs, Inc. All rights reserved.