Foot or Toe Cancer in Dogs
Written By hannah hollinger
Published: 04/01/2016Updated: 07/02/2021
Veterinary reviewed by Michele K.
Foot or Toe Cancer in Dogs - Signs, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Foot or Toe Cancer?
One-third of all dogs get cancer, and it is fatal for half of those. In fact, cancer is the leading cause of death in older dogs (10 years and over). The most important thing about cancer is finding and treating it early. There are several different types of foot and toe cancer in dogs and each have unique signs, causes, diagnoses, and prognoses. For that reason, it is essential to be vigilant with your dog’s health and grooming so you can pick up on some of the subtle changes that can give you early warning of cancer, such as swelling, sores that will not heal, and deformed or missing toenails.
Foot or toe cancer (digital and soft tissue cancer), which can include squamous cell carcinoma, melanoma, osteosarcoma, mast cell tumor, and malignant soft tissue sarcoma is common in dogs. Each of these types of cancer has their own set of signs and treatment, but the main sign in all of these is a swelling or ulcer on the foot or toe. If the cancer is found before it metastasizes (spreads), it is possible that it might be completely contained by amputating the affected toe or foot.
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Foot or Toe Cancer Average Cost
From 64 quotes ranging from $3,000 - $12,000
Average Cost
$7,500
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Symptoms of Foot or Toe Cancer in Dogs
Each type of foot or toe cancer has its own set of signs, which are:
Squamous Cell Carcinoma
  • Swollen toe or foot
  • Sore or ulceration on toe that will not heal
  • Crusted lump on toe/foot
  • Deformed toenail
  • Pain in foot
  • Limping
  • Unable to walk
Melanoma
  • Loose or missing toenail
  • Swelling of foot or toe
  • Sore that will not heal on toe/foot
  • Foot pain
  • Limping
  • Inability to walk
  • Loss of appetite
  • Weight loss
Osteosarcoma
  • Swelling
  • Limping
  • Pain in affected limb
Mast Cell Tumor
  • Swollen toes/foot
  • Pain in toes/foot
  • Sores or ulcer on toes/foot
  • Limping
  • Deformed toe or toenail
  • Nail loss
Malignant Soft Tissue Sarcoma
  • Swelling of the toe/foot
  • Pain in the affected area
  • Large lump in foot/toe
  • Limping
  • Inability to walk
  • Misshapen toe or toenail
 Types
Squamous cell carcinoma is a skin cancer that is usually easy to see and has an excellent chance of survival if found and treated early enough. Malignant melanoma is a fast-moving cancer made up of darkly pigmented skin cells most often in dogs with dark skin and fur, such as the Terrier and Doberman Pinscher. Osteosarcoma is a common bone tumor found most often in giant dog breeds, such as Great Danes older than seven years. Mast cell tumor is a change in malignancy of the cells that affect allergic reactions that affect Bulldogs and Boxers most often. Malignant soft tissue sarcoma is a connective tissue disorder usually right under the skin that is easily detected by owners when grooming or petting.
Causes of Foot or Toe Cancer in Dogs
Squamous cell carcinoma
  • Exposure to sunlight and UV light
  • Dark coated dogs (Black Labrador, Poodle)
  • Large dogs (i.e. Rottweiler, Black Labrador, Giant Schnauzer, and Standard Poodle)
Malignant melanoma
  • Unlike people, it does not seem to be caused by the sun
  • Dark skinned dogs with dark fur (i.e. Terrier, Doberman Pinscher)
Osteosarcoma
  • Giant breeds (i.e. Great Dane, German Shepherd)
  • Older dogs (over seven years old)
Mast cell tumor
  • Boxer
  • Bulldog
Malignant soft tissue sarcoma
  • Unknown
  • Large breeds (i.e. Doberman Pinscher, Rottweiler, Labrador)
Diagnosis of Foot or Toe Cancer in Dogs
The veterinarian will do a complete and thorough physical examination including body temperature, blood pressure, and heart rate. You should be prepared to give the veterinarian your dog’s complete medical history, when the signs started, and whether the signs have gotten worse. Any changes in diet, exercise, and personality should be noted as well. The veterinarian may also need to run some tests on your dog, such as:
  • Complete blood count (CBC)
  • Blood gas
  • Blood chemistry panel
  • Urinalysis
  • Stool sample
  • Fine needle aspiration of swelling or lump
  • Biopsy
  • Digital radiographs (x-rays) of affected area and possible areas of spread
If the veterinarian suspects the cancer may have spread he may need to do some more tests, such as an MRI, CT scan or ultrasound.
 
Treatment of Foot or Toe Cancer in Dogs
Squamous cell carcinoma and malignant melanoma can both be treated by immediate removal of the affected area. If the cancer has metastasized (spread) amputation of the toe, foot, or limb is necessary and depends on how much the cancer has spread. Osteosarcoma usually requires surgery to remove the affected toe, and possibly the foot as well. Mast cell tumors are graded low, intermediate, or high after removal, and may require more tissue or the entire limb being amputated. Chemotherapy is usually recommended if the grade of the tumor is intermediate or high. Malignant soft tissue sarcoma is graded between low, intermediate, and high. Low and intermediate are treated with surgery to remove the tumor as well as the tissue surrounding the area. Chemotherapy and radiation therapy may also be needed for both intermediate and high-grade.
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Recovery of Foot or Toe Cancer in Dogs
The recovery chances for your dog depends on the type of cancer, grade of the tumor, and if it has spread. In many cases, if you have found the cancer early and were able to get treatment right away, chances of recovery is good. Unfortunately, some of these cancers are fast moving and recurring so the survival rate may only be about 10 to 12 months. Be sure to follow up with your veterinarian when you are supposed to and always let him know if there are any changes in your dog’s condition.
Foot or Toe Cancer Average Cost
From 64 quotes ranging from $3,000 - $12,000
Average Cost
$7,500
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Foot or Toe Cancer Questions and Advice from Veterinary Professionals
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Maltese
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Nine Years
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5 found this helpful

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5 found this helpful

My pet has the following symptoms:
Toe Sore
Maltese has a lump on her paw. Not sure what it is or if it’s serious.
Dec. 10, 2020
Answered by Dr. Sara O. DVM
5 Recommendations
Hello this does look serious and I would have it looked at by your vet. Growths in this area can be very hard to remove and should be removed sooner than later
Jan. 1, 2021
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Labrador Retriever
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dog-age-icon
Thirteen Years
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22 found this helpful

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22 found this helpful

My pet has the following symptoms:
Redness
My dog had been limping on his swollen back right paw for about 3 weeks now. My vet said it is cancer but ran no test. We did 5 days of medicine and the swelling stayed the same. They stuck a needle in it and nothing came out. Can he tell it’s cancer just by feeling it ? The pet had 2 surgeries last year for tumor removal on the front chest and side both no cancer.
Sept. 26, 2020
Answered by Dr. Michele K. DVM
22 Recommendations
Thank you for your question. I apologize for the delay, this venue is not set up for urgent emails. They cannot tell if it is cancer by feeling it, no. They may have strong suspicions based on what the mass looks like and your dogs age, but the only way to tell for sure what is going on would be to biopsy it. That is something that you can either talk to your veterinarian about, or get a second opinion.
Oct. 15, 2020
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Mixed
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dog-age-icon
9 months
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2 found this helpful

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2 found this helpful

My pet has the following symptoms:
Lump On Foot
Small lumps showed up 5 days ago. Pup is holding up foot when standing, but walks fine. It seems painful. Vet probed first bump which had a small scab and didn't find anything. Put him on novox for pain and antibiotic. 2nd bump showed up yesterday. It's small and smooth - not ulcerated. Any help is appreciated!
July 16, 2020
Answered by Jessica N. DVM
2 Recommendations
Thank you for reaching out. If the problem is not improving I highly recommend reaching out to your veterinarian to follow up. Your veterinarian may need to do some further testing to assess what the cause of the lumps are since therapy is not causing resolution of them. I hope he feels better soon!
July 16, 2020
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Labrador Retriever
dog-name-icon
Alfie
dog-age-icon
2 Years
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15 found this helpful

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15 found this helpful

My pet has the following symptoms:
Redness
Lump
Iritating
Bubble Like
My 2yr old lab has a medium size lump on his toe is circle and red not painfull no limping just irritating soft to touch but he keeps nibbling it bit hun in it look like it is filled with some fluid and it sits on his toe between his web paws
Aug. 8, 2018
15 Recommendations
Without examining Alfie I cannot determine whether the lump is something to be concerned about or just due to some localised irritation; you should place a cone on Alfie to prevent further nibbling and bathe the area twice per day with a dilute antiseptic and apply a little Neosporin, if there is no improvement or it gets worse visit your Veterinarian. Regards Dr Callum Turner DVM
Aug. 8, 2018
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Rottweiler
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Teegan
dog-age-icon
7 Years
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0 found this helpful

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0 found this helpful

My pet has the following symptoms:
Redness
Limping
Swelling,
Overgrown Nail
Broken Nail
Hello, my dog was just diagnosed with cancer in one of her toe. Teegan is a 7 years old female Rottweiler mix in really good overall health. She is scheduled to have the toe completely removed tomorrow. The reason why I’m reaching out to you is to get your opinion on this situation. Her veterinarian has done a chest X-ray and found no other sign of cancer and is confident that after removing that toe that the chance of her developing another tumor are slim. I’d like to know from your experience if it is in fact rare that another tumor will appear after one was removed. Thanks for your time. Max
July 31, 2018
0 Recommendations
It really depends on the type of tumour on the toe, there are different types of cancers which may be benign or malignant and different malignant tumours spread at different rates; there are varying statistics on recurrence and spread but again it depends on the specific type of cancer. Regards Dr Callum Turner DVM
Aug. 1, 2018
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Jack Russell Terrier
dog-name-icon
Wilson
dog-age-icon
9 Years
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3 found this helpful

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3 found this helpful

My pet has the following symptoms:
Ulcerated Tumour
My 9 year old Jack Russell has a lump behind his front paw pad which became ulcerated quite quickly. Biopsy came back clear but it would not clear up with steroids etc. We tried all sorts of medications. We got a second specialist opinion and had the mass removed. Because of the location it couldn’t be removed totally and unfortunately it was cancerous. We knew it would grow back eventually and was prepared to have his leg amputated as and when it became uncomfortable for him. Unfortunately he then lost his eyesight quite rapidly (within a couple of months). We now do not think we can amputate his leg now that he his blind as his quality of life will be very limited so will make the decision to have him sadly PTS when the time comes. Is this the right thing to do?
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Beagle
dog-name-icon
rodney
dog-age-icon
9 Years
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0 found this helpful

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0 found this helpful

My pet has the following symptoms:
Licking
My dog is having surgery on Mon. We will find out whether it is cancerous or benign. What are the odds that this will turn out benign. He has large mass in between toes. The vet will remove and take out toe. His blood work came out great no elevated white or red blood cells.
Foot or Toe Cancer Average Cost
From 64 quotes ranging from $3,000 - $12,000
Average Cost
$7,500
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