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- Compulsive licking
- Drop in appetite
- Easily startled
- Excessive tail chasing
- Inappropriate eating
- Inappropriate elimination
- Lethargy
- Obsessive chasing behaviors
- Overeating
- Oversleeping
- Pacing
- Unwarranted aggressive displays
- Selective Serotonin reuptake inhibitors - Often used in canines for generalized fears and obsessive-compulsive behaviors, medication such as Prozac and Zoloft
- Tricyclic antianxiety, antidepressant medications - Medications such as Clomicalm, a drug specifically designed to help treat separation anxiety in dogs, and Elavil, fall into this category, and are commonly used to treat both anxious and obsessive behavior in canines
- Benzodiazepine derivatives - Drugs like Xanax and Valium are effective for the temporary relief of anxiety disorders as these medications have a relatively quick action, but dogs often build up an immunity to these compounds, making them less suited for long term use
- Monoamine oxidase inhibitors MOAI - This medication is used in an attempt to counteract the effects of Canine Cognitive Dysfunction
- Dietary supplements of carnitine, lipoic acid, antioxidants, and omega-3s, have also been found to be effective in controlling the degradation of this disorder
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