Histiocytoma in Dogs
Written By hannah hollinger
Published: 11/15/2016Updated: 08/11/2021
Veterinary reviewed by Dr. Linda Simon, MVB MRCVS
Histiocytoma in Dogs - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Histiocytoma?
These growths are common skin tumors that appear on dogs, and are usually self-healing dermal growths singular in number. They are often seen in younger dogs but do occur in canines of any age. The most common site where these growths can occur on your dog is on the head, ears and limbs. They appear as raised lumps that move freely when touched, and may become ulcerated. Most resolve themselves over time without treatment, but surgical removal is an option if it is causing a problem for your dog.
A histiocytoma is  an external buttonlike growth on your dog that is hairless or with an ulcerated surface. These are usually benign and are not painful.
Youtube Play
Histiocytoma Average Cost
From 257 quotes ranging from $300 - $2,000
Average Cost
$800
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Symptoms of Histiocytoma in Dogs
  • Usually a small raised button like growth that appears on the head, ears or limbs 
  • Often it is a single lump but there can be more
  • The lump is painless, usually hairless and the lump moves freely when touched
  • When they first appear, they grow rapidly within the first 1-4 weeks
  • They may become ulcerated or infected, especially if your dog starts to lick or ‘worry’ the site causing it to bleed and allowing infection to set in
Types 
There are generally two types of histiocytomas in dogs. The small button like growth is the most common, and is usually harmless, unless they become ulcerated or infected. Generally, these growths occur mostly in younger dogs and disappear over time without any treatment. 
The other variety are called fibrous histiocytomas and are not well understood. Some soft cell tumors of this type are malignant (cancerous) but they are rare in dogs. They are firm and lumpy in appearance and can be quite large. These growths require surgical treatment.
Causes of Histiocytoma in Dogs
  • Not a lot is known about how or what stimulates these growths but the majority seem to be harmless and self-heal given time
  • Usually occurring in dogs under six years of age, and are possibly the result of growth spurts in the younger canine
  • These growths are not true cancers where the cell growth is uncontrollable, but are more of an overgrowth of cells during the growing years of your pet
  • No virus or infectious agent has been found to stimulate the growths, but insects such as ticks could transmit the stimulus through biting and sucking, which could be spread from dog to dog
Diagnosis of Histiocytoma in Dogs
Diagnosis depends on getting a tissue sample to be able to examine it under a microscope. This is a simple procedure that can be carried out without taking much time.
Your veterinary caregiver will use a needle or a punch biopsy to take a bit of tissue for examination. What that means is they will take a minute sample from the growth so that they can view cells under the microscope and determine the type of cell activity that is happening. The decision for treatment can then be made. 
Dogs that are most at risk from histiocytoma growths are the English Bulldogs, Scottish Terriers, Greyhounds, Boxers, Boston Terriers, and Chinese Shar Peis. If  that is your dog's breed,  be aware and have the veterinarian check them for these conditions.
Treatment of Histiocytoma in Dogs
Usually these growths self-heal, and if the tumor is not malignant or if it is not worrying your dog, then leaving it alone and monitoring its progress is the easiest solution. Your veterinarian will explain everything to you and will advise a regular check up to monitor the growth. 
Any ulceration needs the attention of the veterinary care giver to clean and treat the wound so that it doesn’t become worse. If infected, a medicated wash and antibiotics may be issued.
 If the growth is malignant (much less common) or is in an area where it is annoying your dog, it can be removed surgically. Your dog may need to stay in the hospital overnight and will need recovery time after surgery. In addition, if it is malignant a small area around the growth will be removed, as well as the growth itself, to ensure all the cancer has been removed. The larger and rare fibrous histiocytomas will need to be surgically removed, with the animal under anaesthetic, and stitches will be needed.
Petted logo

Worried about the cost of treating your pet's symptoms?

Pet Insurance covers the cost of many common pet health conditions. Prepare for the unexpected by getting a quote from top pet insurance providers.

Get a quote

background
Recovery of Histiocytoma in Dogs
Keeping your dog from licking or biting the tumor will help prevent any inflammation or bleeding. If the area is ulcerated, taking great care to keep it clean and to stop the dog licking the growth is important. If the tumor has been removed you need to keep the site dry and clean, make sure any bandaging is kept dry, and report any swelling or bleeding to your veterinarian. Recovery is usually very quick after removal, with attention to the wound important in the first few days afterward, and a repeat visit to the clinic to assess the healing.
Histiocytoma Average Cost
From 257 quotes ranging from $300 - $2,000
Average Cost
$800
arrow-up-icon
Top
Histiocytoma Questions and Advice from Veterinary Professionals
dog-breed-icon
Lab/Pitbull mix
dog-name-icon
dog-age-icon
Nine Years
thumbs-up-icon

7 found this helpful

thumbs-up-icon

7 found this helpful

My pet has the following symptoms:
N/A
Our dog Nala has developed this strange growth on her front right leg. It looks scary! Is this something that needs immediate attention?!!
March 3, 2021
Answered by Dr. Maureen M. DVM
7 Recommendations
Hi, Growths have different causes. It could be an accumulation of fat, blood, pus or it could be malignant. The best way to diagnose is to have your vet have a look and perfume biopsy to determine if it's cancerous on not. Most malignant growths are usually attached to the muscle tissue while lipomas are found just beneath the skin.
March 3, 2021
Was this question and answer helpful?
dog-breed-icon
Pit Bull
dog-name-icon
dog-age-icon
Three Years
thumbs-up-icon

20 found this helpful

thumbs-up-icon

20 found this helpful

My pet has the following symptoms:
Histiocytoma
How long does it take to heal and when should i be concerned if it isnt going away but looks like it is getting infected?
July 31, 2020
Answered by Jessica N. DVM
20 Recommendations
Hello- If your dog has a histiocytoma it can take anywhere from 8 to 12 weeks to resolve on its own. If at that point it is not gone it would be a good idea to have it surgically removed. If there is evidence of infection I would recommend taking him to your veterinarian so they can prescribe antibiotics and an E-collar to keep him from licking. Have a good evening.
July 31, 2020
Was this question and answer helpful?
dog-breed-icon
Mini Schnauzer Chin
dog-name-icon
dog-age-icon
Eleven Years
thumbs-up-icon

2 found this helpful

thumbs-up-icon

2 found this helpful

My pet has the following symptoms:
Just The Small Growth
I looked up the growth on line and became scared because it looks just like melanoma.
July 29, 2020
Answered by Dr. Sara O. DVM
2 Recommendations
Hello, Schnauzer commonly gets warty growths like these and they are benign. It would be best for your vet to stick a small needle in this growth and make sure that it is not cancerous. There is no way to tell just by looking at a mass that it is cancerous or not.
July 29, 2020
Was this question and answer helpful?
dog-breed-icon
Chihuahua
dog-name-icon
dog-age-icon
Ten Years
thumbs-up-icon

4 found this helpful

thumbs-up-icon

4 found this helpful

My pet has the following symptoms:
Histiocytoma
My dog has a histiocytoma. It’s a red knob on his left limb. He’s licking it. It has gotten red and then it hasn’t gotten smaller. Some pus was released. I thought it was healing but I wasn’t sure.
July 26, 2020
Answered by Dr. Michele K. DVM
4 Recommendations
Thank you for your question. A histiocytoma in a 10 year old dog would be quite unusual, is that is typically a tumor of younger dogs. If your dog has a red lesion that is not getting better, it is probably not a histiocytoma, and it would be best to have your dog examined by a veterinarian. They will be able to look at the lesion, take a sample if needed, and let you know what needs to be done. I hope that all goes well for your dog.
July 26, 2020
Was this question and answer helpful?
dog-breed-icon
Pitt mix
dog-name-icon
dog-age-icon
7+
thumbs-up-icon

5 found this helpful

thumbs-up-icon

5 found this helpful

My pet has the following symptoms:
Large Lump
Painless lump that oozes blood.
July 26, 2020
Answered by Dr. Michele K. DVM
5 Recommendations
Thank you for your question. A lump that oozes blood is concerning. Even if it is not painful, it may be a problem. It may need to be removed, and having that done sooner rather than later would be better. Since I cannot examine your dog or see the lump, it would be best to have her seen by a veterinarian, as they can examine the lump, take a sample if needed to see what kind of lump it is, and let you know what the options are for treatment. I hope that all goes well.
July 26, 2020
Was this question and answer helpful?
dog-breed-icon
Mixed
dog-name-icon
Ace
dog-age-icon
7 Years
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
None
We have a 7 year old mixed breed dog that developed a firm pink nodule on his L front leg, vet wants to try 10 days of simplicef and rimadyl and if nothing happens then to do a punch biopsy or just remove it. Would a FNA be better to figure what it is first before removing it to ensure good margins in case it’s a MCT?
dog-breed-icon
German Shepherd
dog-name-icon
Morpheus
dog-age-icon
5 Years
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Lump
Irritation
Hi, my dog Morpheus is a 5yo GSD. I noticed today he has been licking at his leg and I found a small pink lump. Very very little bleeding (likely from him licking at it). After some research I believe this to be a histiocytoma. I've read that itching means it's in the healing process. Since I've read up I've prevented him from messing with the area. I wiped it down with a little peroxide and covered it with a bandage. Does covering it with a bandage prevent it from healing?
dog-breed-icon
Labrador Retriever
dog-name-icon
Leo
dog-age-icon
1 Year
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Ear Lump
My dog got bit in the ear by a younger dog while playing and now has a lump on his ear. It has been 2 months and it has not gone away. Should we wait longer or do we need to have it surgically removed. We did some research and are worried it might a Histiocytoma but we are not sure.
Histiocytoma Average Cost
From 257 quotes ranging from $300 - $2,000
Average Cost
$800
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Need pet insurance?
Need pet insurance?

Learn more in the Wag! app

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install


© 2025 Wag Labs, Inc. All rights reserved.


© 2025 Wag Labs, Inc. All rights reserved.