Hello! Camo is a neutered male mini Schnauzer mix aged about 10-11 yo. In 2009 he was probably 2-3 and began having seizures. Vet placed him on K Bromide, it did not alleviate seizures so I discontinued it after four months. Lethargy appeared along with seizures and has increased with time while seizures rarely occur any more and when they do they are mild and transient. Poor spatial sense developed as well as stiffness in neck and sadly hypersensitivity to gentle touch on neck as well as forelimbs. Exaggerated pain response is VERY evident in forelimbs, over time slight bowing of forelimbs has occurred with a limp/shuffle predominantly on left side of body. Left eye is prone to conjunctivitis like symptoms; thick ropy mucous overproduction in left eye only and only occurs intermittently since Spring 2018. Progressive paralysis of rear legs, extreme sensitivity to heat, sun, and now has advanced to intolerance of even moderate climate changes. Intermittent tremors, visible muscle spasms in both rear legs. Inability to sense left rear leg, probounced knuckling of left leg if he has a good day and can stand on his own. Known skeletal problems: expanded cervical vertebrae which impacted spinal cord, surgery performed April 2018 to decompress region, fenestration of surrounding vertebrae done as well to prevent future constriction of cervical spinal cord. Confirmed IVDD in caudal region, surgery was recommended and will likely occur before Christmas. Voracious appetite to the point of pica along with excessive lethargy and incessant panting led to diagnosis of Pituitary Dependent Cushing’s 2015 and subsequent treatment with daily Trilostane for approximately two years. Exercise intolerance increases with time. Within the past 2 years Camo has had repetitive functional urinary retention which progressed to requiring manual expression several times daily. Distended abdomen, oversize bladder that has thickened, swollen kidneys and consistently high liver values. Fecal incontinence development since 2015; and seems unaware that he is pooping whatsoever most of the time. Cervical decommission surgery did allow him to sometimes recognize he needs to poop and he does alert me on those times otherwise he is just as surprised as I am when poops come out. Joint supplements were suggested by vet and given by me once per day for at least 18 months from 2015-2017. Supplements had MSM, Boswellia, Glucosamine Chondroiton in a base of desiccated beef liver. Canned pumpkin added to diet in order to regulate unpredictable irritable bowel episodes. Fed consistent diet of Orijen Senior dry kibble for several years, recently switched to organic turkey breast meat or organic chicken boiled at home w safe fruits and veggies like apple slices, blueberries, spinach, chia seeds, etc. Current medications are: 1mg diazepam 3x daily for bladder emptying but I have seen no improvement of sphincter release even on 2mg 3x daily. Prazosin 1mg 2x daily, caused extreme loss of gait control as well as narcolepsy and syncope. Dropped Prazosin dose to 1mg once daily but still seeing bad side effects with zero therapeutic effects. Gabapentin 100mg 2x daily, does not appear to ease his hyperesthesia nor general disconfort, causes coma-like state so dropped dosage to .75mg 2x daily hoping to reduce his time spent in a drugged out daze. Anipryl once daily dose for 20 lb canine since April 2018 with an incredible improvement of his overall happiness and seemed to relieve some pain too, but fizzled out by late July and now seems as ineffective as giving him a placebo, but displays noticeable withdrawal signs if Anipryl is withheld so still taking it daily despite loss of therapeutic results. On to therapy: After three weeks of strict post surgical crate rest began with ROM exercises several times per day. Slowly increased amount of time he was allowed to stand and walk around to avoid injuring his recovering spine. Worked up to sand walking early in mornings three times a week as well as jetpool therapy twice weekly on alternating days with sand walk. Endless muscle massages. Vast improvement in mobility and mindset immediately following commencement of physical therapy. Reached a plateau 3-4 weeks ago and did not just plateau he dive-bombed downhill within a matter of days. Visits to local vet uninformative, told to see the neurologist now waiting on pins and needles for that appointment. I’m hoping for some hope. Recommended vaccinations at recommended intervals. Seems to get kennel cough from the kennel cough vaccine lately but my vet is using some newfangled (Vanguard?) oral vaccine all of the sudden. Camo has hyperpigmentation on his skin, inexplicable yellowing patches on what was soft white fur, asymmetrical patches of darkened hair in addition to a shocking amount of flesh toned cutaneous warts suddenly appearing. Lately displays some level if disorientation, especially if subjected to change in ambient temperature as well as momentary confusion over change in surroundings. Inappropriate vocalization began a week ago, he now occasionally barks at what I assume are the ghosts he “sees”. Barks at animals on the television and sometimes barks at outside noises he happens to hear, he NEVER barked at random things...”be quiet” and “Camo talk” were the first commands he learned and never broke. He is developing a fondness for secluded quiet places and will suddenly decide he HAS to be alone then drags his rear legs and crawling underneath my bed with increasing frequency. Some cognitive dysfunction is suspected in my Mom diagnosis. Possible vision disturbance in left eye, that is also the eye that rolls backwards into the socket so all I see is a white creepy fluttering left eye while right eye maintains normal control and stays closed while asleep. Heavy snoring, some sleep apnea, oh and apparently in 2014 God decided to curse this sweet boy with nightmares so he literally has night terrors about once every 2-4 months. Immediately after waking up screaming he seems to be blind and also temporarily deaf he just stares blankly for a bit then slowly comes back to reality. My frustration with this is that I noticed symptoms and brought him to his doc every single time like a good Mom but it seems the medical plan is to throw pills at the individual symptoms in an effort to medically manage each symptom. Ok great whatever my Master’s is in Business so I trust medical professionals to do what is right since I’m not qualified in that field. I keep asking for a reason, run tests, do some diagnostics, I will pay you whatever it costs just find the root problem and we can make a plan to solve it instead of doping Camo up and praying he doesn’t notice he is losing control of his own body. I’m onto a theory that he had chronically high levels of vitamin A considering the “premium” food he ate as well as his love for boiled eggs, the beef liver joint supplements and the liberal use of pumpkin per advice from his doctor. How would you go about this if he were your patient? Is there a SOP to discover if he in fact does have vitamin A toxicity? Can he be tested for over accumulation of all fat soluble vitamins and if so, what kind of measures would you take to detoxify him of whichever ones he has as you hypothetical patient? Chelation? Carbon? Acupuncture? Please help us