Renal Dysplasia in Dogs
Written By hannah hollinger
Published: 12/01/2016Updated: 10/29/2021
Veterinary reviewed by Dr. Linda Simon, MVB MRCVS
Renal Dysplasia in Dogs - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Renal Dysplasia?
This condition can affect the canine unilaterally or bilaterally, for animals affected bilaterally the prognosis is often grave, with death occurring soon after birth. For dog’s who have been affected unilaterally the prognosis is also poor, with treatment aimed at managing the subsequent renal failure and providing the best quality of life as possible.
Renal dysplasia is a defect that has been reported in many breeds including the Chow Chow and Malamute. This condition develops in the womb during renal development. In the normal development of the kidneys, ureter muscles grow from the kidneys and branch out to form a network of urine collecting tubules. In a fetus affected with this condition the tubules fail to branch out, instead causing urine build up and cysts to form. These cysts eventually replace the kidney.
Youtube Play
Renal Dysplasia Average Cost
From 369 quotes ranging from $500 - $8,000
Average Cost
$4,000
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Symptoms of Renal Dysplasia in Dogs
Signs of this disease may include failure to thrive from birth, polyuria and polydipsia and other symptoms seen in chronic kidney disease including:
  • Constipation
  • Vomiting and nausea
  • Lethargy
  • Anorexia
  • Bad breath
If your dog is presenting with uremic crisis (the dangerous buildup of toxins in the blood stream due to inadequate toxin removal from the bloodstream by the kidney) symptoms may include: 
  • Weakness and collapse
  • Muscle tremors
  • Diarrhea
  • Vomiting of dried blood
  • Neurological signs
Causes of Renal Dysplasia in Dogs
Renal dysplasia in dogs is considered a familial disease in certain breeds. This condition is caused by a defect in utero during the development of the kidneys, leading to immature glomeruli, primitive tubules and lesions caused by cysts. 
The onset of this disease can be in the neonate or young puppy from between 6 months and 2 years of age. 
There appears to be a strong breed predisposition in the following breeds:
  • Alaskan Malamute
  • Beagle
  • Boxer
  • Chow Chow
  • Great Dane
  • Bulldog
  • Irish Wolfhound
  • Samoyed
Diagnosis of Renal Dysplasia in Dogs
Your veterinarian will perform a full clinical examination of your pet. Signs such as a small body size for age, rubber jaw, failure to thrive, or a history of kidney failure in your dog’s family may suggest this condition. 
If your veterinarian suspects this condition she may perform radiographs of the abdomen. In cases of renal dysplasia, small or irregular kidney shapes may be seen as well as a poorly mineralized skeleton, pathological fractures due to renal osteodystrophy, and the appearance of floating teeth in the skull.
Your veterinarian may take a blood sample to perform a biochemistry panel which will show increased urea and creatinine due to the body’s reduced ability to remove these toxins from the blood stream. They will also check the kidney's urine concentrating ability by analysing the specific gravity (concentration) of the urine.
Treatment of Renal Dysplasia in Dogs
Unfortunately, there is no cure for this disease, however the treatment is very similar to that of chronic kidney failure and aimed at managing the disease and providing the best life quality for your pet. 
If your dog is experiencing uremic shock, intravenous fluid therapy may be given to treat the shock and correct dehydration.
Other treatments that may be given are: 
  • Anti-emetics if your pet is vomiting
  • Subcutaneous fluid therapy for chronic maintenance 
  • Potassium supplementation 
  • Oral bicarbonate may be considered to address metabolic acidosis 
  • Treatment to manage hypertension
  • Phosphate binders
  • Appetite stimulants
Petted logo

Worried about the cost of treating your pet's symptoms?

Pet Insurance covers the cost of many common pet health conditions. Prepare for the unexpected by getting a quote from top pet insurance providers.

Get a quote

background
Recovery of Renal Dysplasia in Dogs
Unfortunately, the prognosis for this condition is not good, with deterioration expected within months of diagnosis. A phosphate restricted diet may be recommended for your pet. Specific kidney diets have shown to maintain or improve nutrition, delay the onset of uremia, slow progression or development of other complications, and extend expected life time. 
These renal diets should contain:
  • Carefully balanced levels of phosphate, as this mineral is metabolized by the kidneys
  • Reduced levels of salt as studies have shown the reduction of salt intake to slow the rate of progression of the disease 
  • Low quantities of high quality protein. Protein breakdown leads to toxic waste products in the blood stream that require processing by the kidneys for excretion through the urine
Providing a diet that contains low levels of high quality protein means a reduced amount of waste for the kidneys to process while the pet’s energy requirements are met. Your pet will require regular examinations to monitor for signs of uremia such as ulcers. 
As this disease is degenerative, life quality assessment is a major aspect of care, and it may be recommended as the disease progresses to euthanize your pet to relieve suffering. In cases where the birth parents and littermates are known, it is recommended that screening tests are carried out and that breeding from affected canines ceases, as this is a known genetic disease.
Renal Dysplasia Average Cost
From 369 quotes ranging from $500 - $8,000
Average Cost
$4,000
arrow-up-icon
Top
Renal Dysplasia Questions and Advice from Veterinary Professionals
dog-breed-icon
Golden Retriever
dog-name-icon
dog-age-icon
One Year
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Excessive Thirst
Our dog has a seizure due to water toxicity and becoming hyponatremic and there was an accidental finding of renal dysplasia. She is 1 years old and very happy pup! The ER said her creatinine was 5 and over 48hr of IV therapy it only went down to 4.1. She is still in the icu after three days. We are heart broken and told we only have 3 months left with her. What can we expect at home when she comes home? Is there any interventions we can do or is too late? Has anyone ever had this problem with their pup and was able to live longer than the expected? Any advice helps greatly!! Thank you!
July 27, 2020
Answered by Dr. Michele K. DVM
0 Recommendations
Thank you for your question. I am sorry that is happening to your dog, that is very sad. Unfortunately, without knowing more details about your dogs situation, it is very difficult for me to comment on prognosis or Outlook. Since the veterinarian taking care of your dog is familiar with her case, they would be the best person to ask this question of, as they can offer advice as to things that you can do at home, different foods that may help, or what to expect. I hope that you have more time with her.
July 27, 2020
Was this question and answer helpful?
dog-breed-icon
Greyhound Mix
dog-name-icon
Ranna
dog-age-icon
2 Years
thumbs-up-icon

23 found this helpful

thumbs-up-icon

23 found this helpful

My pet has the following symptoms:
Depression
Mouth Odor
Hot Spots
Mouth Ulcers
My dog Ranna is in end stage renal dysplasia. When I adopted her two years ago when she was 4 months old she had issues with a leaky bladder. We took her to the vet to have some blood work done to see if maybe she had an infection from her spay procedure. We were told she had bilateral renal dysplasia and that we shouldn't expect her to live past her 1st birthday. She is now 2 1/2 and her life is slowly coming to an end. Currently, she is experiencing mouth ulcers and mild depression. When we go out to do something new she perks up and acts like her old self, but when we get home she collapses in our laps and stares at us with sad eyes. We are trying to figure out the right time to say goodbye. It's hard to decide because she does have some life left in her and she's still a puppy, but when we're home she's not the same dog. She also has fits of diarrhea and vomiting, but most times she is able to keep her food down and has solid bowel movements.
Aug. 31, 2018
Was this question and answer helpful?
dog-breed-icon
Bullmastiff
dog-name-icon
Peanut
dog-age-icon
9 Months
thumbs-up-icon

8 found this helpful

thumbs-up-icon

8 found this helpful

My pet has the following symptoms:
Lethargic, Off Her Feed.
I have a nine month old puppy diagnosed with bilateral renal dysplasia. We are dealing with it. What do I do about the rest of the litter and the parents? Is there a test for this? Dam is 2.5, sire is 4. At the moment both parents and the rest of the litter appear healthy? Don't want to frighten all the other puppy owners. What do I do?? What should I expect?
May 6, 2018
Answered by Dr. Michele K. DVM
8 Recommendations
There is a genetic test for renal dysplasia, though I am unsure as to the validity of the test at this time. Your veterinarian would be able to give you more information on it - it would be a good idea to see if the rest of the litter is affected.
May 6, 2018
Was this question and answer helpful?
dog-breed-icon
Boxer
dog-name-icon
Luna
dog-age-icon
1 Year
thumbs-up-icon

6 found this helpful

thumbs-up-icon

6 found this helpful

My pet has the following symptoms:
Bone Pain
My 1 year old white boxer Luna, was diagnosed with renal dysplasia about a couple weeks ago. We’ve put her on pain meds and other medication to lower her protein levels along with other levels. She was doing a lot better since we switched her diet and got her on the pain meds. But, now in the past couple days she seems to have declined. She doesn’t seem interested in her dry dog food (even when mixed with wet food), she’s been shivering like a leaf, and now constantly swallowing, along with drooling. But it looks like she’s having a hard time swallowing and trying to throw up. Tonight she managed to cough up white mucus about 4 times and then puked up a good amount of food with saliva and white mucus. Is there anything I can do or any medication to help with throwing up and the shivering?? She looks extremely uncomfortable.
May 6, 2018
6 Recommendations
There is a medication which may help, but it isn’t available over the counter and you would need to see or call your Veterinarian to explain the change in Luna’s symptoms for them to consider whether or not to prescribe. You should let Luna rest for the time being and just give her water, reintroduce food (possibly some boiled rice) after a few hours. Regards Dr Callum Turner DVM
May 6, 2018
Was this question and answer helpful?
dog-breed-icon
Goldendoodle
dog-name-icon
ocean
dog-age-icon
2 Years
thumbs-up-icon

16 found this helpful

thumbs-up-icon

16 found this helpful

My pet has the following symptoms:
Lethargy
hi our dog was diagnosed with bilateral renal dysplasia. She is 2yrs old without any symptoms other than her lab values. Since changing her diet her creatinin level went from 2.3 to 2. Her BUN went back to normal levels and we will continue to monitor her lab work with routine checks. What other lab value should I be looking out for when assessing if her condition is getting worse? Specific gravity was also on the low side. Can dogs live a full life with this condition? pLease help
Feb. 23, 2018
16 Recommendations
Due to the progressive nature of the condition, it is a case of keeping and managing the symptoms and the diet as best as possible; eventually the level of kidney degeneration will result in the worsening of symptoms and consideration of euthanasia. Two two important values to look out for are BUN and creatinine, which are the best indicator of renal health. Regards Dr Callum Turner DVM
Feb. 23, 2018
Was this question and answer helpful?
dog-breed-icon
cockapoo
dog-name-icon
Biggie
dog-age-icon
3 Months
thumbs-up-icon

1 found this helpful

thumbs-up-icon

1 found this helpful

My pet has the following symptoms:
Lethargic
Excessive Drinking
Hi all, would be grateful for some guidance. Biggie is a 3 month old Cockapoo who seemed normal apart from excessive drinking of water and he was struggling to be house trained (mind you he is a puppy so this seemed normal at the time). He has been diagnosed with Congenital Kidney Disease via ultrasound after an initial blood test. Any advice on anything I can do to prolong his life i.e diet etc etc would be appreciated? What has worked well for other? This really is the cruelest disease, I am heartbroken.
dog-breed-icon
Appenzeller Sennenhund (Mountain Dog)
dog-name-icon
Ruby
dog-age-icon
5 Months
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Incontinence
Our Appenzeller puppy has been diagnosed (via Ultrasound) with bilateral renal dysplasia and ectopic ureters at 18 weeks old. The breeder has been notified - (I am not sure if this makes a difference, but our puppy was the runt of the litter, and the dam was bred accidentally in her first heat.) We noticed that our puppy had excessive thirst and we had a lot of trouble housebreaking her; she often would trickle pee when distracted and not only when greeting people or excited. At other times, she could pee normally. She's a delightful fun puppy - she loves hikes and plays football in the garden with our kids. She is so loving! Her urine and blood levels for now are slightly elevated for BUN and phosphorous - creatinine is fine. But she has had frequent urinary tract infections requiring antibiotics. We went to a specialist clinic that wanted to do a CT scan and possibly operate on the ureters to see if that improved her kidneys. However we are completely alarmed t the expense involved: $2,100 for the CT scan? thousands for the surgery? We had been planning to spay her and correct an umbilical hernia but now are faced with such high medical bills for her; even this morning's urine culture and med cost $280. What level of care seems optimal for this situation? I don't think we have a good guarantee that surgery will correct the ureters and thus I hesitate to do more than another ultrasound with Doppler and then just keep an eye out for infections and treat them as they occur. It's so heartbreaking not to know what is best in this situation and to be faced with such astronomical costs. I also wish I had a better sense on prognosis and life-expectancy and also whether or not to still spay her and correct the hernia regardless of whether we elect to do further surgery. Any thoughts or insights?
Renal Dysplasia Average Cost
From 369 quotes ranging from $500 - $8,000
Average Cost
$4,000
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Need pet insurance?
Need pet insurance?

Learn more in the Wag! app

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install


© 2025 Wag Labs, Inc. All rights reserved.


© 2025 Wag Labs, Inc. All rights reserved.

Wag! Premium service

Get Wag! Premium & save on all services

Health & Wellness

Chevron down icon

Become a Caregiver

Chevron down icon

Wag! App

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install

Wag! for Pet Parents

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install

pet-parent-illustration

Pet Caregiver

Find pet care jobs on Wag!

Approved Caregiver?

Get the app