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- Tumor of the Uterus in Dogs
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- Abdominal pain and swelling
- Loss of appetite
- Visible weight loss
- Vomiting
- Constipation
- Excessive sleepiness
- Weakness
- Depression
- Increased thirst and frequent urination
- Incontinence
- Blood in urine
- Lack of interest in exercise or playing
- Canine leiomyomas are usually benign (non-cancerous), and affect older female dogs that have not been spayed
- Canine leiomyosarcomas are malignant (cancerous), and affect females of any age that have not been spayed
- Endometrial hyperplasia (overgrowth) of the uterus is usually due to stimulation by the natural female hormone progesterone, which remains elevated for up to two months after estrus in the dog
- External sources of estrogen and progesterone (sometimes given medically for control of estrus cycles) can also induce the same pathology
- Previous uterine infections
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