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What is Hypoglycemia?

Hypoglycemia most commonly occurs in cats with diabetes. This is because a diabetic cat requires a diligent, daily routine of timed feedings, injections and moderate exercise. Any upset to the routine or misapplication of insulin can lead to the cat going into a hypoglycemic state. A cat who has been previously diagnosed with diabetes can also go into diabetic remission within the first four months of treatment and no longer need injections. This can easily lead to overdosing the cat with insulin. 

Rarely, a cat who does not have diabetes can become hypoglycemic. This is often due to problems with the liver or pancreas, and in some cases can be caused by an infection of the blood. If the cat becomes unconscious, the situation is a medical emergency. 

Sugar is naturally processed in the body by the hormone insulin, which is produced in the pancreas. If too much insulin exists in the body, either from injections if a cat has diabetes or from the pancreas overproducing the hormone, blood sugar levels can become too low for normal body function. While other organs can use fat or protein if sugar is scarce, the brain requires glucose to operate. When levels of glucose in the bloodstream drop below 60 milligrams per deciliter, a cat is referred to as hypoglycemic. The brain then begins to rapidly lose function. This condition can be fatal if not addressed immediately.

Symptoms of Hypoglycemia in Cats

In the early stages of low blood sugar, a cat may only produce subtle symptoms. If you have a diabetic cat, be sure to learn the beginning signs of hypoglycemia. If blood sugar is not raised in time, certain damage to the brain may be permanent. Symptoms to watch for include:

  • Increased appetite
  • Vomiting a green/yellow bile (indication of pancreatitis)
  • Dilated pupils
  • Tachypnea (rapid breathing)
  • Restlessness
  • Anxiety
  • Weakness
  • Lethargy
  • Staggering
  • Shivering
  • Twitching muscles
  • Confusion
  • Dizziness
  • Head shaking
  • Seizures
  • Coma

Causes of Hypoglycemia in Cats

Generally, the cause of hypoglycemia in cats is related to the cat having diabetes. Disruption of a diabetic routine or insulin administration errors are often responsible for dangerously low blood sugar. In cats who do not have diabetes, liver and pancreas issues are usually to blame. Rarely, no cause will be identified. Known causes include:

  • Too high of insulin dose
  • Multiple insulin dose administration
  • Not enough food intake
  • Excessive vomiting
  • Lack of appropriate blood level monitoring
  • Diabetic remission
  • Too much exercise
  • Addison’s disease
  • Pancreatitis
  • Liver disease
  • Insulinomas (tumors on the pancreas that secrete insulin)
  • Sepsis (severe infection of the blood)

Diagnosis of Hypoglycemia in Cats

If you know that too many insulin doses have been administered to your cat, bring the cat to a veterinary clinic or animal hospital at once to consult a veterinarian. All medications, insulin doses, and the cat’s full daily routine will need to be made known to the vet. If no routine disruption has occurred, the cat’s full medical history will have to be provided and a complete physical examination will be performed. Glucose levels of the blood will be checked to determine how severe the hypoglycemia is. 

If the cat is not diabetic, the underlying issue will need to be identified. This diagnosis will take place after the cat has already been stabilized with treatment. Full blood work including a complete blood count and a biochemical profile will need to be run. This can reveal signs of infection or the presence of cancer by determining how many white blood cells are in the blood. Urinalysis may be used to gauge the function of the kidneys, liver, and pancreas. X-rays can help locate any abnormalities or tumors on the organs. An ACTH stimulation test may be used to determine how the adrenal glands are responding. 

Treatment of Hypoglycemia in Cats

A hypoglycemic cat needs to have its blood sugar raised significantly to be able to have enough fuel within the body to perform basic functions. If the cat is not diabetic, the underlying issue may also need extensive treatment. 

Oral Glucose Administration 

If your cat has begun to exhibit severe symptoms of hypoglycemia, you may be advised to administer a form of glucose to the cat before you bring it in for emergency care. This may be needed for the cat to survive the trip to a veterinarian. The glucose solution should be applied to the cat’s lips and under its tongue. Corn syrup or honey may be used for this process, but not table sugar.

IV Fluids 

An intravenous administration of a dextrose solution may be needed to restore significantly low levels of blood sugar. Hospitalization is required for this process, and the cat will need to be monitored every one to two hours after IV treatment to be given a small portion of food. This must be done until insulin levels return to normal.

Recovery of Hypoglycemia in Cats

Most cats recover from hypoglycemia after appropriate treatment has been given. If brain damage has occurred, it is permanent in most cases. Your veterinarian may determine that insulin doses should be reduced in some scenarios. It is best to have regular appointments every 3-4 months to have a veterinarian monitor a diabetic cat’s blood levels. 

Keeping a daily log of a diabetic cat’s routine can prevent inconsistencies from developing. Only one person should be in charge of administering insulin injections to avoid overdose. Monitor blood and urine glucose levels daily to ensure there are no changes in the cat. Always keep corn syrup or honey easily accessible to prevent a diabetic emergency. If your cat is not diabetic, ongoing care may be needed to help restore normal liver or pancreas function. Sepsis treatment may involve antibiotic and other medication administration.

Hypoglycemia Questions and Advice from Veterinary Professionals

Maine Coon
16 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms


Medication Used

Pro zinc

My cat is 16 years old and has been diagnosed with diabetes for 7 years now. Within the last 4 months he has been going hypoglycemic. Especially at night. I have even lowered his dosage. Most days he's fine. But it's almost an attack once a week. Is it his old Age that he cannot be regulated?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2959 Recommendations
Diabetes can be a complicated condition to manage at the best of time, in complicated cases like this you should be taking regular blood glucose readings and plotting them on a graph to make a glucose curve to make sure that the insulin given is an appropriate amount. Also, dietary management, timing of insulin administration and dosage is important to managing the condition effectively. You should discuss this with your Veterinarian at your next check up. Regards Dr Callum Turner DVM

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Simease mix
2 Months
Moderate condition
0 found helpful
Moderate condition

Has Symptoms


My kitten just had a seizure and began to meow a lot. He is acting some what fine now. The vet had previously said he has low blood sugar. Is there anything i can do at home for him?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2959 Recommendations
If Salem appears to be having a hypoglycemic episode it would be best to put a drop of corn syrup or honey into his mouth, but afterwards you should visit your Veterinarian for a discussion on the low blood glucose levels and what options you have for management long term. Regards Dr Callum Turner DVM

I have a 4 week old bottle baby who has had 2 episodes of hypoglycemic coma. The finder was feeding her infant s imilac with high iron before she came into my foster So I suspect liver damage as the cause. Any suggestions? My local vet doesn't seem to know what to do.

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American long hair
15 Years
Moderate condition
-1 found helpful
Moderate condition

Has Symptoms


My female cat who is 15, and diabetic for 8 yrs. she was on 1.5 of Vetsulin 2x a day. About 5 weeks ago she did not seem herself, so I called our Vet and he examined her and did blood work and said she was in remission and now she tends to run low? The meter says low and I got her up to 78. She is eating and seems to be drinking more. Not sure what is going on waiting to hear from our Vet

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2959 Recommendations
The control of diabetes is a delicate balance with two animals being different and things may change regularly; if there have been changes to the blood glucose levels it would be good to do a glucose curve to see what the levels are throughout the day to see if any adjustment of insulin is needed. Regards Dr Callum Turner DVM

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13 Years
Moderate condition
0 found helpful
Moderate condition

Has Symptoms

dilated pupils
Fast Breathing

My 13 year old ginger tom cat is diabetic and is on insulin twice daily - 3.5 units in the morning and 3 units in the evening. He has been diabetic for 3 years now and during that time has suffered about 5 hypoglaemic attacks. His recent fructosamine test results were 349 which is apparently deemed 'good control'. When he is experiencing a hypo his pupils are dilated, his breathing relatively fast and he slowly paces the room in a confused states swinging his head slowly from side to side - are these symptoms typical of a hypo and am I right to rub honey on his gums? His hypos typically last about 3-4 hours. Should I be home testing his blood glucose levels and can this be done with a human blood glucose meter. Any advice would be greatly appreciated. My vet said there is no need to see him again for another 6 months.

Dr. Michele King, DVM
Dr. Michele King, DVM
1385 Recommendations
Thank you for your email. Without seeing him, I can't comment on whether those might be hypoglycemic episodes, but it is possible. If he responds to the honey or corn syrup on his gums fairly quickly during one of those episodes, then it probably is one. If he does not respond, he may be having some other type of neurologic event - if you are able to video the episode, that might be helpful to your veterinarian. If he is having episodes of hypoglycemia, his diabetes is not well controlled, and he should be seen sooner than 6 months to figure out what is happening with his blood sugar. You can test at home, there are glucometers that are calibrated for animal readings that your veterinarian can get for you and show you how to use. I hope that he does well.

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American Shorthair
8 Years
Critical condition
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Critical condition

Has Symptoms


Medication Used

Maropitant Citrate

I have a cat (Bumbas) who is almost 8 years old. She has been experiencing very low blood sugar levels, around 32-50, as tested by a vet. Her test for insulinoma came back negative around 2 weeks ago. Her whole life, she and her brother have had Origen dry cat food, along with bottled water, with sporadic doses of colloidal silver in their water; however, I have halted colloidal silver for the time being, as of a few days ago. Although I am on a fixed income and disabled, I have done my best to try to ensure that they have high quality cat food.

She has been experiencing seizures, drooling, lethargy, weak hind legs, loss of appetite (although she has been eating wet cat food this morning for a change), low pitch moaning, anxiety-like symptoms (where she hisses randomly, fluffy tail, shortness of breath, etc.). She was approximately 15 lbs., but has dropped down to about 13.5 lbs. from lack of appetite.

I first noticed that she had an issue around 3 months ago when her hind legs would not allow her to run. She stumbled over herself. Her seizures have grown to be a daily occurrence, sometimes multiple times a day. I am racking up veterinary bills and can no longer afford them, as I am on a fixed income and disabled. The vets suspect that it might be cancer of some sort, or possibly a tumor on her pancreas that is causing an unnatural release of insulin. I have had to rub caro syrup on her gums while she was experiencing seizures, which is difficult, as she can also be aggressive sometimes.

She is now experiencing multiple seizures a day, as her condition has worsened exponentially within the past couple of weeks. However, I am worried that sugar like that might trigger further release of insulin.

What can I give my cat that will naturally balance her blood sugar levels and not trigger further release of insulin? I hope to find a natural cure for her condition and would greatly appreciate natural alternatives, as prescription drugs are very expensive and have not seemed to always work. Thank you for your feedback.

Dr. Michele King, DVM
Dr. Michele King, DVM
1385 Recommendations
Thank you for your email. I am sorry that Bumbas is having this problem, that is quite unusual. Addison's disease is one test that you did not mention, I'm not sure if your veterinarian tested for that, as it is very unusual in cats. Without seeing her I cannot recommend any supplements or diet changes to help with her blood sugar levels, but since low blood sugar can be a life threatening condition, it would be wise to have NutriCal or another brand of quick energy/sugar supplement on hand, as you have been doing. Your veterinarian should be able to suggest possible treatments in the short term, though it is difficult since you don't really know the underlying cause. I hope that Bumbas does okay.

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