Enlarged Liver in Dogs

A little over three weeks ago now, Brutus, our 8-year old 90lb pitbull-boxer mix, presented with constipation. His energy level and food intake were very low but would eat table scraps if offered and was still drinking water. He went 3 days without having a bowel movement before we took him to the vet. Constipation was not abnormal for him. Usually a little white rice, hamburger and pumpkin seemed to do the trick. This time it did not. CBC panel at the vet's determined that his liver was not happy. He had elevated bilirubin and very high white blood cell levels. X-ray confirmed that he was not plugged up. Sent home on denamarin, metronidazole, ursodiol, prednisone, and cerenia. However, an official diagnosis was not made. About day 2 of being on medication he came back to life, not nearly normal but back. His appetite was back, he dint enjoy taking medication but dealt with it. His energy level was back to about 90% about 7 days in on medication. He actually wanted to play. 2 weeks after being on medication he took a turn for the worse. Within 24 hours he was back to being weak, no appetite, no energy, minimal bowels movements, and breathing was heavy (his breathing was normal prior to first vet visit). Took him to emergency clinic because our family vet was on vacation. They did x-rays and confirmed enlarged liver, charged me for an ultrasound even though the doctor on site was not able to read it, sent home on amoxicillin, ciprofloxacin and a pain killer. Symptoms got worse. We tried holding out until our family vet was back (Tuesday) and unfortunately, he passed away last night. Towards the end, he sounded very congested. Couldn't walk more than 3 steps without becoming weak and plopping to the floor. He refused water and food. He was vomiting bile. And at the very end, it seemed like he was trying to vomit but nothing was coming up. His tongue turned green when he was gone. What happened overnight to make him so much worse than he was originally?

I have a goldendoodle who is 12.5 years old. He has never been sick, not even a cold. I took him in to the Vet last night because he was acting sluggish. Upon our checkup, I was told that he has lost 12 pounds in less than a year and that is ALP is 601 and his ALT is 2,000. He is not symptomatic at all. I can't get over the readings. To have an ALT at 2000 is unbelievable, but he acting fine. He is getting an ultrasound tomorrow. My question is why is his ALT at 2000 and the doctor's are not acting right away. Instead, I'm waiting 2 days to get his ultrasound. I love him dearly. Could it be a false reading? I was also wondering why they didn't do a urinary test on him? The xray did show an informality on his liver. These two days are taunting me. Anything would help.

For the past 8 months, my 7 year old rotty has had difficulty pooping. She seems constipated, trying to poop as she walks. Small bits drop and eventually, she'll have explosive diarrhea. We have tried everything, including a colonscopy. First vet gave her Cimelgex which we determined caused her to bleed internally, resulting in bloody diarrhea. Second vet was convinced that her dysplasia and spine cause her pain keeping her from squatting. Prescribed Carprofen, but no improvement. Bloody drops throughout the house. She definitely has an intolerance to NSAIDS. Most recently, a new vet opened her up thinking she had an enlarged spleen that needed to be removed. Spleen was ok, but liver was swollen with "stones". Vet believes she may have been kicked or hit by a car as a young dog creating stones. (The whites of her eyes have always been yellowish) Her swollen liver is now causing pain that makes it difficult for her to squat. For these past 2 weeks following surgery, she was definitely better, especially the first 2 days I felt like I got my dog back. She was playful and happy again. As of 2 days, she is no longer on meds, and this morning she is back to the same problem - unable to poop and sad mood has returned. Any suggestions would be greatly appreciated!

I just got back from my vet. Stewie my 9yoa Boston terrier had his senior panel done. His alkp was 1766 vet was concerned and wanted an ultrasound. Results came back with an enlarged liver and 1 enlarged adrenal gland and an enlarged heart. He has been slowing down lately pants a lot but great appetite. No weight loss. Still my sweet baby! That want to test for Cushings but I am reluctant. Stewie’s medical history was an intestinal blockage that perforated on table! They told me it was a miracle that he survived the surgery! 1 year later he had another blockage but was manually manipulated and cleared. Not sure where to turn.

I have a 9 year old Australian cattle dog jack Russell mutt, female. Two weeks ago, overnight, she became restless and was shaking and panting quite a bit. Started having difficulty walking down the stairs. She progressively became unable to walk seemingly because of pain over the next few hours. We took her to the vet and she had a 103.3 fever, back pain, abdominal pain, delayed response in her back leg. Xrays were normal, tick tests negative, blood results showed high WBC (26.6) with high neutrophils (24206) and high monocytes (1064), high ALT (235) and high ALP (171). They thought maybe liver infection. We had been camping two days before where she had been bitten by ticks (we live in NYC). They gave rimadyl and doxycycline for 2 weeks. She has been drinking more water (waking us up at night to have water) and a bit sore now and then. We finished the prescription this Saturday. We went on a long walk on Sunday and she again struggled to walk, eventually we had to carry her to give her a break. Does Lyme disease or liver infection seem right? We were thinking we would retest her blood in 2 more weeks, giving time for potential Lyme disease to show up.