My baby boy (15yrs) wasn't himself beginning in Oct but I thought it could be that he knew I was leaving for 1.5 weeks for vacation when he saw my suitcase (I had 2 babysitters for him while I was gone). Before I adopted him he had the majority of his teeth removed. He was also diagnosed with a grade 2/6 heart murmur. When I got home from vacation I definitely noticed he wasn't good. His eating and water intake decreased. I took him to the vet (Nov 11) and she did blood work, urinalysis and a stool specimen. He was found to have an increase in white blood cells and he was dehydrated. His BUN was 32 and Glucose was 202 -everything else was normal. They gave him a Convenia injection and Subcutaneous Fluid Therapy and I took him home vowing to get him to eat and drink. I tried giving him all kinds of food (tuna, chicken, etc) but he still didn't want to eat much and his balance was a huge concern with me so 4 days later I took him to another vet. They reviewed his blood work and other than going through an ultrasound, the diagnosis was dehydration, bacteruria, mild hyperglycemia without glucosuria and murmur. This vet gave me Mirtazapine (food stimulant) and Gabapentin Capsules for pain. The first night I gave him the entire pill and he was flopping all over the place so I realized a whole pill wasn't a good amount for him so I'd give him just a tiny bit and he wanted to eat. He wanted whatever I was eating but he just didn't seem interested in more than "picking at" his food. He was drinking water but not like he used to - he was a huge water drinker and diabetes was ruled out last year. As the days went by he was getting weaker and weaker. He'd still get on my bed and sleep with me, he'd get up on the back of the couch and chairs but he wasn't able to control his rear legs. They would come out from underneath him. On Nov 30th I noticed how yellow the inside of his ears were (his nose and mouth was yellowish but I thought it was the dye from the cat food) and then I looked at his paw pads and his eyes and realized he was extremely jaundiced. I called the vet and made an appt. At that point he just looked tired and worn and I realized he wasn't going to get any better. Still to this day, I have no idea what the main issue was, but I've to realize the lack of eating led to the liver issue. Now I'm questioning if the Pure Silicone I sprayed on the inside of his litter box (twice) to keep the litter from sticking to the side of the box had something to do with his demise. I didn't do it while he was around but did it get on the litter and then through his skin? Was those two times enough to cause this? I'm beating myself up thinking his demise was my fault.