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It is considered hepatic failure when a dog’s liver has lost more than 75% of its function, a secondary occurrence to liver death (also called necrosis). As the liver cleans and detoxifies blood, stores reserves of nutrients and is responsible for producing hormones that regulate multiple processes, dogs experiencing hepatic failure may also experience dysfunction in many other systems, and other organs may be impacted. Hepatic failure may cause a variety of problems to include fluid in the abdomen of your dog, digestive ulcers, increased susceptibility to infection and liver-related brain disease. Immediate treatment is necessary in cases of acute hepatic failure, which can occur suddenly or be the end state of chronic liver disease.
Whether acute or resulting from chronic long-term liver disease, when the liver has lost more than 75% of its function, hepatic (liver) failure will be diagnosed.
There are a variety of symptoms of hepatic failure that can be seen in your dog. The first signs that are typically seen in hepatic failure are:
More severe symptoms may constitute an emergency requiring immediate attention. These include:
Hepatic failure may happen suddenly or develop slowly. Acute hepatic failure can occur in conjunction with any condition that affects the liver; for example, hepatic failure can be caused by poisoning if the toxins taken in by your dog are more than what his liver is able to handle. Hepatic failure can also occur as a result of long term, chronic liver disease where the disease progresses slowly, but over time your dog will develop symptoms of hepatic failure.
There are a number of conditions that may lead to acute hepatic failure in your dog. Poisoning is a common cause of hepatic failure. Types of poisoning include:
Infectious diseases to include:
Other causes of hepatic failure include:
Hepatic failure can occur in any breed of dog, regardless of its gender or age.
Your veterinarian will conduct a full physical examination and ask you what symptoms you have noticed and when you first noticed them. If your veterinarian is not familiar with the medical (including medications) and family history of your dog, he will seek to determine whether there are any known conditions that may be contributing to his symptoms. It is likely that you will be asked if your dog could have been exposed to poison. Your veterinarian will request a complete blood count, biochemical profile and urine sample to get an understanding of the dysfunction and cause of his symptoms. Other tests that may be conducted are:
Immediate treatment is necessary should your dog be experiencing hepatic failure. Your veterinarian will first treat the symptoms your dog is experiencing and stabilize his condition. This will often involve intravenous fluids and electrolytes in order to decrease the toxicity of your dog’s blood. A diuretic or enema may be used to clean out your dog’s system. If there is excessive fluid in your dog’s stomach, your veterinarian may remove some of it and if there are issues with clotting your dog may require a transfusion as well as a medication like heparin or vitamin K.
Once your dog is stabilized and your veterinarian understands the underlying issue or issues leading to your dog’s hepatic failure, he will be able to determine the best course of treatment.
Poisoning - Your dog’s condition may resolve itself once the toxins have been flushed from his system
Bacterial and fungal infections - Antibiotics or antifungal medications may be prescribed
Cancer and cysts - Depending on the health of your dog, surgery may be recommended once he is stabilized; chemotherapy is an option for some types of cancer
Chronic hepatitis - Long term medication to assist in reducing problems with copper storage
If your dog has experienced hepatic failure it is important to administer the medication that your veterinarian recommended and make appropriate changes to his diet. Regular follow up appointments will be required so that your veterinarian can keep an eye on his progress.
It will be important to provide your dog with nutritional support and manage his diet in order to assist in his recovery from hepatic failure. For example, a low protein, low sodium diet served in small frequent meals will help minimize the stress on your dog’s liver. There are specific foods available for dogs who have problems with their liver. Antioxidants, zinc, B vitamins, Vitamin C and Vitamin E may also be recommended to help liver function.
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Hey, My dog has serious problemes. 1 month ago it was diagnosed with pancreatic insufficiency and hepatic insurgency. After 1 month the problem with diarrhea was solved but when we repeat the analysis we found serious increase to the hepatic elements. He has Gpt/alat 517. 1 month ago it was 209. The doctor chose Hepatiale Forte to solve the problem but as we can see there no good sign. Now he sustain that the problem cand be the fact that he has a malabsorbation and maybe the medicine doaesn't made the effect because of it. We give him the medicine in the food. Now we increase the medicine, before we give him 2 caps on day, now we give him 4. It's these a good solution and it's maybe the malabsorbation the reason why my dog doesn't resoond to the medicine?
Oct. 6, 2017
I am not familiar with Hepatiale Forte so I Googled it, Hepatiale Forte is composed of: Oily seeds, oily fruit and their derivatives, Phospholipids (phospholipidum ex soja) containing phosphatidylcholine, and ornithine as L-ornithine L-asparginase. I am not sure about the oily seeds, fruit and their derivatives as this may have an effect on the pancreas; but the L-ornithine L-asparginase has shown as being effective in dogs with hepatic encephalopathy. Supplementation with pancreatic enzymes and liver support (Silybin and SAMe) may help to assist with recovery; I would discuss with with your Veterinarian. Regards Dr Callum Turner DVM http://vetexpert.pl/eng/produkty/hepatiale-forte/
Oct. 7, 2017
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