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- Jaundice (yellow color in the whites of the eyes and skin)
- Fluid retention (seen as swollen belly)
- Coughing (gagging)
- Exhaustion (tired all the time)
- Breathing difficulty (labored or erratic breathing)
- Diarrhea (runny stool)
- Pain in the abdomen (guarding the belly)
- Appetite loss (refusal to eat)
- Weight loss
- Excessive sleepiness
- Not wanting to play or exercise
- Prehepatic portal hypertension (portal vein) can be described as resistance in the extrahepatic portal vein
- Intrahepatic portal hypertension (liver) is increasing resistance in the portal vein branches, sinuses, and hepatic veins
- Posthepatic portal hypertension (heart, vena cava, hepatic vein) is known as blockage of the larger hepatic veins, vena cava, or right atrium
- Congenital (Cocker Spaniels, Doberman Pinschers, Rottweilers)
- Cirrhosis
- Pancreatitis
- Blood clot
- Constricted blood vessel
- Peritonitis
- Abdominal neoplasia
- Small portal vein
- Corticosteroids
- Enlarged lymph nodes
- Cancer
- Side effect of shunt repair operation
- Congenital (German Shepherd, Terriers, Dalmation, Cocker Spaniel, Doberman Pinscher, Retrievers)
- Recurrent bile duct blockage
- Excess fibrous tissues in the liver
- Liver cirrhosis
- Cancer
- Chronic inflammation
- Fistula in the liver
- Heart disease (congestive heart failure)
- Heartworms
- Tumor in the heart
- Pericardial effusion (fluid in the pericardium)
- Serious blood clot in lung
- CBC (anemia, platelet cell counts)
- Coagulation parameters (blood clotting time, fibrinogen, antithrombin, and protein)
- Urinalysis
- Fine needle aspiration of abdominal fluid
- Liver enzyme (increase of liver enzyme activity)
- Liver function (blood ammonia, total serum bile acid)
- Portal vein pressure
- Digital radiographs (x-rays)
- Liver biopsy
- CT scans
- Ultrasound
- Scintigraphy (portosystemic hepatic bypass)
- Angiography (hepatic arteriovenous fistula)
- Portal vein issues can be treated with surgery (glue embolization of the fistula) or medication (Isosorbide 5-mononitrate)
- Liver disorders can be treated with surgery (liver lobectomy) or medications (nadolol)
- Heart failure can be treated with surgery (stents, embolectomy) or medication (thrombolytic, anticoagulant)
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