Neospora Caninum in Dogs
Parasitic Infection (Neosporosis) in Dogs - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Neospora Caninum?
There are many silent killers in this world, and cancer is usually the first one we think of. However, that is not the only silent lurker when it comes to pet disease. Neosporosis is a very deadly parasite that lives in infected cattle, mostly. This is important to note for pet owners that feed their pets raw diets or possibly live on ranches.
Neosporosis parasites start as unsporulated oocytes, which are passed through feces, water, food, or soil. Once ingested, they live in the body and become sporulated. The final, and deadliest, is when they are fully grown into tachyzoites.
Neosporosis can affect any species of animal, whether they are domestic, captive, or wild. Neosporosis is also widely known to affect unborn animals, just like toxoplasmosis.
Canine Neosporosis is a microscopic protozoan parasite with worldwide distribution. A disease similar to toxoplasmosis, it attacks animal’s brain and spinal cord and slowly shuts down their body. Neospora caninum is a very deadly parasite that should not be taken lightly. Be aware of your dog’s whereabouts and do not feed them raw beef if at all possible. It could be a simple step in saving their life against a tragedy. If you are the owner of cattle as well, vaccinate your livestock to help prevent the spread of this deadly disease.
Neospora Caninum Average Cost
From 367 quotes ranging from $200 - $500
Average Cost
$250
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Symptoms of Neospora Caninum in Dogs
As with most parasitic diseases, symptoms may not always be prevalent until it is too late. When symptoms do show, they come on very quickly and progress rapidly. One account of a pet owner whose dog received Neosporosis after eating raw hamburger mince was that the symptoms showed up after only two days. Symptoms include:
  • Hindlimb paralysis (commonly in puppies)
  • Ulcers
  • Pneumonia
  • Peritonitis - an infection of the lining of the abdomen after a rupture
  • Hepatitis
  • Staggering
  • Slow reflexes or reaction time
  • Blindness
If you recognize any of these symptoms, take your pet to the veterinarian immediately. If it is caught in early stages, they can give your dog medicine to help treat the symptoms of neosporosis.
Types
There is only one kind of neosporosis, and that is neospora canum. Even though the disease is mostly spread by infected cattle, there is no other form of this parasite. It is very closely related to Toxoplasma gondii, which made it difficult to diagnose for years.
Norway was the first country to distinguish the difference between the two in the mid-1980s, naming Neosporosis as a muscular degeneration type disorder. Since its increase of cases and further studies, veterinarians now have the ability to tell the difference between Neosporosis and toxoplasmosis.
Causes of Neospora Caninum in Dogs
As previously mentioned, Neospora canum is transferred mostly by infected livestock, particularly cattle. This can be because a dog eats an infected, aborted placenta or from eating raw beef. Dogs will contract the parasites from eating tissue of an infected animal that has the parasite cysts in it.
Once the dog eats the infected flesh, the oocytes bursts and the life cycle starts all over again. The parasites create new oocytes in the dog’s body, which are shed through feces and then the cattle eat the infected soil which causes a full circle.
Diagnosis of Neospora Caninum in Dogs
There are many steps to diagnosis Neosporosis as it must be checked with complete accuracy. Without careful scrutiny, your pet could be misdiagnosed and not given the proper treatment. When in the hospital, your vet will perform tests such as:
  • Biopsy
  • PCR/Immunohistochemistry
  • Serum Antibodies
  • Smears
The veterinarians will use a polymerase chain reaction (PCR) to check for disruptions in the pet’s DNA due to parasites in the tissues. This is the most common and effective way to check for Neosporosis, although some veterinarians will do various biopsies to check tissues for parasites as well.
Treatment of Neospora Caninum in Dogs
Unfortunately, there is no full treatment for Neosporosis. If in small puppies, young dogs, or senior dogs the paralysis has already set in, it is too late. There are a set of drugs that can be given to help ease symptoms and provide comfort for your pet, but it is likely they will not recover.
The drugs that are commonly prescribed for Neospora caninum are clindamycin for about 4 weeks up to 8 weeks. They may also prescribe trimethoprim-sulfadiazine and pyrimethamine. For puppies, if one puppy is diagnosed, it is important that a pet owner distributes treatment to littermates before symptoms start showing.
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Recovery of Neospora Caninum in Dogs
Puppies have a very low prognosis as do senior dogs. For them, it is better that you just keep them comfortable and give them their full medication until the end. The pet owner in the previously mentioned story made the decision to put her pet to sleep to reduce its suffering.
For puppies, it is hard to prevent the disease as it is contracted congenitally, however, you can help prevent it in older dogs by keeping them away from livestock and not feeding them raw beef. This reduces the risk of them contracting the disease accidentally.
There is a vaccine that livestock owners can give their cattle to help prevent the contraction of Neosporosis. It is 81% effective, which is a great deal better than leaving cattle unvaccinated. This could be the future of keeping both cattle and canines safe.
While there have been no reported cases of Neospora caninum affecting humans, it is probably better that pregnant women should have minimal contact with infected dogs or cattle. Because it is related to toxoplasma gondii, which is transmitted through cats, there is a chance it could have the same effect on unborn humans as well.
Neospora Caninum Average Cost
From 367 quotes ranging from $200 - $500
Average Cost
$250
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Neospora Caninum Questions and Advice from Veterinary Professionals
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shepherd/boxer
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Crown
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3 Years
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1 found this helpful

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1 found this helpful

My pet has the following symptoms:
Crippled, Rear Legs, Incontinent
I have a shepherd/boxer mix that was brought to me after being found in a box roadside. He could not stand steadily on his rear legs, worked with him, never really steadied. Took him to to university vet clinic, did a neurological exam. Opinion was probably an infection of some type in very early puppyhood that caused this problem. He is currently three years old, still cannot use one rear leg, kind of uses the other to hop on. Question is could this be neospora, he is in excellent health otherwise. Thank you for your time.
June 27, 2018
Answered by Dr. Michele K. DVM
1 Recommendations
Neospora or other infections of the meninges as a young dog that was not treated could lead to long lasting damage. I'm glad that you were able to keep him and work with him, but I'm not sure that he will regain use of that leg. He may benefit from physical therapy?
June 27, 2018
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Dogo Argentino
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Puma
dog-age-icon
11 Months
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0 found this helpful

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0 found this helpful

My pet has the following symptoms:
Pain
Lethargy
Weakness
Stiffness
I have an 11 mos old Dogo Argentino that I have been treating for suspected SRMA for the past two months. A week ago I noticed a swollen testicle. I did an ultrasound and needle aspirate biopsy and cytology of the testicle. He has been diagnosed with Neospora in his testicle. I am currently weaning him off of Prednisone and am treating with SMZ and Clindamycin. Have you ever had a report of this being in a testicle? Thanks in advance.
Dec. 29, 2017
0 Recommendations
I have never thought at Neospora caninum being present in a testicle and I couldn’t find anything about it either; it is known for causing abortion in some species but I don’t know about it being present in the testicles. Regards Dr Callum Turner DVM
Dec. 29, 2017
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Pointer
dog-name-icon
Pablo
dog-age-icon
approx. 7
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1 found this helpful

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1 found this helpful

My pet has the following symptoms:
Weakness
Neospora
Stiffness In Neck
Apathetic
Pulsation On Head
Hello, we adopted our Pablo from a state animal shelter.He is a male Pointer approx.7 years old and was found weighting only 18kg (now he is 26kg).Pablo was positive on Leishmaniasis and Ehrlichiosis and now was diagnosed positive on Neospora,Toxoplasmosis and Anaplasmosis.We did the tests for Neospora/Toxoplasmosis cause he did have symptoms like Stiffness in the neck (could not bent down to eat), was apathetic and appeared to be in pain when doing certain movments. He is now taking medication for all of those illnesses, his general Blood and cidney test are ok and the medications seam to help at, at least Pablo does not have any symptoms since he takes the medication (exept the pulsation on his head this is still there). My question is: beside the medications he already takes could a blood transfusion be of any help fighting the Neospora and Toxoplasmosis? Many thanks in advance!
Nov. 4, 2017
1 Recommendations
A blood transfusion would be of little or no value in this case unless it was required to help boost red blood cell or platelet counts during some concurrent treatment. Continue to follow the instructions from your Veterinarian regarding treatment and monitor for improvement. Regards Dr Callum Turner DVM
Nov. 4, 2017
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Golden Retreiver
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Ivy
dog-age-icon
4 Years
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1 found this helpful

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1 found this helpful

My pet has the following symptoms:
Minor Head Bobble
Minor Unsteady On Legs
Looks like we have successfully treated neospora with 8 weeks of tablets. No clinical signs for 3 months. However we had a retest and titre levels haven't gone down at all. There doesn't seem to be much research on this available does this mean we are in the all clear or could it come back at any time?
Oct. 31, 2017
1 Recommendations
The problem with Neospora infections is that they may be asymptomatic meaning that a dog can be infected but not show any symptoms; antibody titres are reliable ways of showing the body’s response to an infection but may persist after an infection has been treated, PCR to detect genetic material of pathogens is being developed for Neospora but isn’t widely used. I would continue to monitor the antibody titres and keep an eye for signs of symptomatic disease. Regards Dr Callum Turner DVM
Oct. 31, 2017
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Lurcher
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Damson
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10 Years
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4 found this helpful

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4 found this helpful

My dog has been eating raw meat for years. It has been frozen but contains beef as well as other meats from the butcher's. In Britain, the farming press quotes 51% of cattle as infected. Is there a real danger in continuing to feed it raw, or should I cook it?
Oct. 16, 2017

4 Recommendations
Whilst I understand your concerns, freezing meat will kill the parasite so make sure that you freeze your meat for a few days before thawing; you can start to cook it to cover all bases but freezing is sufficient in killing the tissue cysts. Regards Dr Callum Turner DVM www.fwi.co.uk/livestock/neospora-added-cattle-health-scheme-disease-list.htm www.ncbi.nlm.nih.gov/pmc/articles/PMC1865591/
Oct. 16, 2017
I shall pass on this information to all my dog-owning friends as there is very little on the subject that I can find on British sites. Thank you very much.
Oct. 17, 2017
Damson's Owner
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Golden Retriever
dog-name-icon
Molly
dog-age-icon
2 Years
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0 found this helpful

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0 found this helpful

My pet has the following symptoms:
Seizures
Tremors
Rash
Partial Paralysis
My Golden retriever might have Neospora. Not entirely sure, I need to follow up with another appointment. About a month ago, our dog got a really bad seizure. Took her to the pet ER and they diagnosed her with epilepsy and started her on meds. After three seizure, we noticed her hind legs not acting as normal. Having trouble walk up the stairs. Also notice that the color pigment in her nose changed, showing patches of pink where it ise to be black. Anyways, she had another seizure just a couple of days ago. This time she camp developed sores near her nose that she constantly scratches along with the pigment in her nose going ever more pink loosing its blackness. She has tremors when she sleeps and it seems like her hind legs are struggling more. I starting not to sound like epilepsy and more like nerospora. Will continue to give her anti-convulsion meds, but I am going to bring with up with the vet the next time I see them which will be very soon
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French Bulldog
dog-name-icon
Mir
dog-age-icon
10 Years
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0 found this helpful

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My pet has the following symptoms:
Anxiety
Lack Of Coordination
Dizzyness
Seisures
My 10yo french bulldog has been tested positive for neospora after an MRI and encefalic brain fluid analysis. We're treating him with anibiotics and anti-convulsion medication, because seisures were his main symptom, along with dizziness and difficulty standing. He has improved a lot after 5 days of corticoids and began antibiotics in the meantime. But I'm scared after reading this page, is neospora impossible to treat? He never showed any kind of limb paralysis, the worst were the seisures, which have stopped. Is there hope of a full recovery and being neospora free?
Neospora Caninum Average Cost
From 367 quotes ranging from $200 - $500
Average Cost
$250
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