While puppy strangles is almost never found in adult dogs, it is also rare in puppies, for which it is most likely to occur between three weeks and four months of age. It resembles bacterial infection; however, puppy strangles appears to be is an immune-mediated disease. There is an effective treatment for puppy strangles; however, if it continues untreated, it can lead to permanent scarring and even death. Several breeds of dogs develop puppy strangles at a higher rate: Golden Retriever, Gordon Setter, Miniature Dachshund and Siberian Husky.

While puppy strangles is idiopathic, meaning no cause has been clearly identified, evidence points to the disease as immune-mediated. It appears to be caused by immune dysfunction. Because it occurs more often in certain breeds, it is suspected that puppy strangles or a predisposition to puppy strangles has a genetic correlation.

Diagnosis of puppy strangles can be difficult, as it resembles staphylococcal pyoderma, a common bacterial skin infection. Since puppy strangles is much more rare, there is a chance of false diagnosis of staph infection. An accurate diagnosis depends upon skin cytology, or microscopic examination of biopsies from the affected area and lesions, as well as cytological analysis of joint fluid in order to detect sterile suppurative arthritis, an advanced symptom that manifests itself as joint pain. The veterinarian will also examine deep skin scrapings in order to look for mites, and examine a fungal culture in order to look for ringworm. It is important to determine if any bacterial or fungal infection has formed as a result of the puppy’s compromised immune system and treat those as symptoms of the underlying disease.

Treatment for puppy strangles will primarily be aggressive immunosuppression through corticosteroids, typically with prednisone, accompanied by broad-spectrum antibiotics, such as cephalexin, cefadroxil, or amoxicillin clavulanate, in order to prevent or treat secondary bacterial or fungal infections. In addition to your puppy having a compromised immune system, the exposed tissue from lesions and pustules puts your dog at an increased risk for developing secondary infections. Depending on your puppy’s condition, your veterinarian may also prescribe a topical ointment to soothe pain and itching during recovery.

Along with the veterinarian, monitor the progress of your dog’s recovery. Treating a young puppy with an immunosuppressants is not something to be taken lightly, as puppies already have an immature immune system. For this reason, it’s important that the dose of corticosteroids be tapered off during recovery.

If the veterinarian prescribes an ointment for pain, apply it strictly according to the instructions. The most important thing during treatment will be for you to keep the affected areas dry and clean with a solution of astringent and diluted hydrogen peroxide several times a day in order to encourage proper healing. Known as Burow’s solution, you can purchase under the named Domeboro, Star-Octic and Borofair through your veterinarian’s office or at a drugstore.

Puppy strangles is not likely to recur. Unfortunately, permanent scarring is possible, depending upon how quickly treatment is sought after symptoms develop.

If the puppy has gone untreated too long, the prognosis can be very poor. Prednisone ($40 per 100ct.) is one of the medications your veterinarian may choose and is commonly used to treat inflammatory diseases. They typically will combine prednisone with an antibiotic (Cephalexin, Cefadroxil, or Amoxicillin Clavulanate). Cephalexin 500mg ($30 per 100ct.) is used to treat infections that are caused by bacteria. The combined cost of prednisone and cephalexin is around $70 on average. Cefadroxil ($30 for 50ml. or $60 for 100ml.) is usually in liquid form and is also an antibiotic that is used to treat bacterial infections. The combined cost of prednisone and cefadroxil ranges between $70 and $100. Finally, amoxicillin clavulanate 500mg ($20 per 100ct.) is an antibiotic also used to treat bacterial infections. The combined cost of prednisone and amoxicillin clavulanate is around $60 on average. Combining prednisone and an antibiotic will give your puppy the best chance at a good prognosis.