Skin Bumps (Granulomatous Dermatoses) Average Cost

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What is Skin Bumps (Granulomatous Dermatoses)?

Granulomatous dermatosis is a skin disorder that involves small lesions on the skin with a particular nodular appearance, called granulomas. Granulomas on the skin are generally raised and have a surface that appears grainy to the naked eye. When examined under a microscope a unique cellular pattern can be discerned that identifies the sample as a granuloma. Granulomatous dermatosis can originate in several different ways, and treatment and prognosis for this malady are dependent on the underlying condition.

Granulomatous dermatosis is a skin disorder that involves small raised lesions on the skin with a particular nodular appearance, called granulomas.



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Symptoms of Skin Bumps (Granulomatous Dermatoses) in Dogs

Granulomatous dermatoses are most obviously characterized by small inflammatory lesions that have a nodular appearance. These lesions, called granulomas, can appear on any surface of the body. The granulomas themselves have a distinctive cellular pattern that can be distinguished through microscopic inspection. The symptoms related to granulomatous dermatosis condition:

  • Bald patches
  • Itching
  • Raised or ulcerated bumps on the skin (granuloma)
  • Redness of the skin
  • Scabbing
  • Swelling
  • Tenderness 
  • Thickening of patches of skin
  • Weeping from lesions

Diseases which affect other areas of the body as well as the skin may show additional symptoms.


There are several disorders and diseases that can cause granulomas, or that have granulomatous dermatitis as a symptom. This is a sampling of the types of diseases and disorders with granulomas.

Eosinophilic granuloma

  • A rare disease in canines associated with unusual reactions to insect bites

Lick granuloma

  • This is a granulomatous condition of the skin caused or worsened by a dog compulsively licking a specific spot on their body until a granuloma develops

Juvenile cellulitis (puppy strangles)

  • A relatively rare condition occurring in puppyhood that eventually causes skin granulomas, especially on the face and legs


  • A multisystemic disease that results in the formulation of granulomas that can affect many bodily organs, including the skin

Causes of Skin Bumps (Granulomatous Dermatoses) in Dogs

Because granulomatous dermatoses can arise from a large number of disorders, the causes can be quite diverse.

  • Allergy or sensitivity whereby eosinophilic granuloma and flea allergy dermatitis can both ultimately lead to areas of granulomatous dermatosis
  • Autoimmune disorders like lupus and pemphigus are autoimmune disorders that can affect the skin and cause granulomatous dermatosis to occur
  • Bacterial such as one of the better known bacterial diseases of the skin, leprosy, which often presents with both simple ulcerated nodules and granulomas 
  • Behavioral issues such as lick granuloma can be a behavioral issue, although your veterinarian will want to do tests to ensure there isn’t a medical component involved 
  • Dermal irritant which can be a skin irritation from chemicals such as bleach or fertilizer and can lead to lesions that become granulomatous in nature
  • Fungal invasion like blastomycosis and ringworm which are both fungal diseases that can result in dermal granulomas

Diagnosis of Skin Bumps (Granulomatous Dermatoses) in Dogs

In order to make an accurate diagnosis, your veterinarian will start by asking you about your dog, including any medical history or health concerns, current and previous medications, onset of symptoms, and diet and activity levels. A physical examination of the granulomas and the surrounding tissues will also be done, and they will also want to get a sample of the tissue so that it can be examined more closely. A complete blood count, biochemistry profile, skin scraping and urinalysis are also likely to be done at this time as well. 

Under a microscope, the granulomatous lesions will show a unique cellular pattern. Diagnosing the granuloma itself is usually quite simple once the sample is viewed microscopically, but diagnosing what caused the granuloma can prove to be more elusive. Tests to diagnose the original cause could include biopsy of skin samples, fungal cultures, bacterial cultures, intradermal allergy tests, and x-rays.

Treatment of Skin Bumps (Granulomatous Dermatoses) in Dogs

Treatment methods for granulomatous dermatoses are as varied as the causes of the disorder itself. Bacterial origins will most often be treated with antibiotics in pill form or as a topical solution, and your veterinarian is likely to offer antifungal treatment options of ointments, oral medication, and shampoos for fungal infestations. The medications for fungal disorders are often prescribed for longer periods of time than the antibiotic medication as they can be particularly stubborn to eradicate. Specialized topical treatments such as antihistamines or steroids may be used as well for reactions to irritants to your dog’s skin.

Autoimmune disorders, which may manifest with granulomas on both the skin and other surfaces, are treated corticosteroids to reduce any inflammation and with chemotherapy, using cytotoxic drugs to suppress the immune system. Dogs tolerate chemotherapy better than most humans and only around 5% require hospitalization from the treatment itself. Some breeds (English Sheepdog, Lhasa Apso, Maltese, Schnauzer, Shih Tzu, and Poodle) are more prone to hair loss. If the underlying condition caused internal granulomas that are interfering with optimal health, surgery may be required to remove the tissue as well.

Recovery of Skin Bumps (Granulomatous Dermatoses) in Dogs

The prognosis for your pet is dependent on the underlying cause. It is essential to follow your veterinarian’s instructions regarding any medications and continue them for the full amount of time that is recommended, even if symptoms appear to be under control. If your companion is treated using cytotoxic medication (chemotherapy) your veterinarian will probably want to do regular checks on your dog’s liver and kidney enzyme levels. Pets are often sent home the same day after chemotherapy, and although most of the drug is metabolized within just a few hours, some remnants of it can remain in the blood for a few days. It is important to use gloves when dealing with bodily fluids, and maintain good hand washing hygiene. Children, pregnant and nursing women and immunocompromised adults should avoid contact with the bodily fluids during that time.

Skin Bumps (Granulomatous Dermatoses) Questions and Advice from Veterinary Professionals

Labrador Pitbull
2 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms

Movable lump
Scabby lump

My 2 year old lab pit mix has had a bump on his head for about a year. I can pick it up and move it around so I wasnt super concerned. Over time it started to bald, now its completely scabbed over and pusses and bleeds as the scab sheds. I was given a topical antibiotic for it but was never really told what is was. It looks like a yellow mucus sac under where it cracks. Help!

So I have had to take my dog to get that thing removed for the 3rd time it came back again and she constantly scratches at the scab and makes it bleed every where our vet gave us some pills and sav to give to her it worked at first but she still scratches and licks it she’s about 10 maybe 11. What do I do I don’t want to put her down if It can be fixed.

We had similar situation, in the end decided to make surgery, because cephalosporin that doctor prescribed for some time stopped working, granuloma reached the size of an egg of a hen, and started to double.

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4 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms

Low Energy

We had a tooth cleaning and a bump removed from foot, it's been down hill from there. 4 year old male pug, got yeast on the foot, it spread to both dogs, one was put on some med, didn't heal. Got other advice and quit all meds. He now has bumps coming out in full force.

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Labrador Retriever
8 Months
Fair condition
0 found helpful
Fair condition

Has Symptoms


My large 8 mo old lab has about 1cm hard lump on skin u dear arm. Previously had redness around the skin but now only the lump. Scaly and hard. What could it be? Doesn’t seem to bother him and he can’t lick the area.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3320 Recommendations
It is difficult to say what the specific cause may be, if the lump is on the skin (not under it) we can be certain it isn’t a lymph node or other structure; any lump like this should be seen by your Veterinarian and they may take an aspirate to determine if there is anything inside (cyst, abscess etc…). Regards Dr Callum Turner DVM

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5 Months
Mild condition
0 found helpful
Mild condition

Has Symptoms

Neck Pain

She has bumps on back .legs n eye

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3320 Recommendations

There are many different types of skin bumps and lumps in dogs which may be caused by infections, allergies, contact irritation (from chemicals), parasites, internal disease etc… It would be best to have Onyx examined by her Veterinarian and whilst you’re there you can speak about spaying as well if you are not planning to breed her. Regards Dr Callum Turner DVM

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