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- Blood in the urine
- Difficulty giving birth or mating
- Excessive licking of genital area
- Mass on the vagina (either visible or palpable)
- Straining to urinate
- Vaginal discharge
- Vaginal odor
- Vulvar bleeding
- Advanced age
- Exposure to chemicals
- Infection
- Radiation exposure
- Genetics
- Reproductive status (whether neutered or not)
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