Tumors of the Vagina in Dogs
Written By Grace Park
Published: 06/02/2016Updated: 07/01/2021
Veterinary reviewed by Dr. Linda Simon, MVB MRCVS
Tumors of the Vagina in Dogs - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Tumors of the Vagina?
Tumors of the vagina are the second most common form of female reproductive tumor and can be either benign or malignant. Most vaginal lesions or tumors are non-cancerous leiomyomas or fibroleiomyomas, but certain malignant cancers can develop in the skin of the vagina as well so it is important to alert your veterinarian if you see signs of a tumor on or in your dog’s vagina. Canine transmissible venereal tumors, a type of cancerous canine tumor that can be spread from dog to dog by touch, can form in this area as well.
Tumors of the vagina and vulva are the second most common form of reproductive tumors in female dogs. Unspayed female dogs are more likely to develop these tumors.
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Tumors of the Vagina Average Cost
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$7,500
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Symptoms of Tumors of the Vagina in Dogs
Vaginitis is an inflammation of the vagina which can result in discharge, itching and pain. This inflammation can occur separately or concurrently with vaginal tumors. 
  • Blood in the urine
  • Difficulty giving birth or mating
  • Excessive licking of genital area
  • Mass on the vagina (either visible or palpable)
  • Straining to urinate
  • Vaginal discharge
  • Vaginal odor
  • Vulvar bleeding
Types
There are many types of tumors that can affect the vagina and vulvar area on dogs, both benign and malignant. The most common tumors to affect the vagina are leiomyomas and fibroleiomyomas; benign tumors of the smooth muscle that generally do not spread. Fibropapillomas, small, warty bumps that are caused by a viral infection, may also develop in this area. They tend to look similar to other tumors in this area, however they often regress spontaneously after a few months. Malignant tumors are rarer, but squamous cell carcinomas may also develop on the skin in this area, and clitoral adenocarcinoma may affect your canine’s clitoris. Canine transmissible venereal tumors are cauliflower-like, nodular or papillary and can also affect the genital area. They are often inflamed and ulcerated, making it quite contagious particularly if direct contact has occurred during mating, licking or rough play.
Causes of Tumors of the Vagina in Dogs
The causes of most cancers can be somewhat ambiguous although there are some things can increase the likelihood for cancers to develop:
  • Advanced age
  • Exposure to chemicals 
  • Infection 
  • Radiation exposure
  • Genetics 
  • Reproductive status (whether neutered or not)
There is a hormonal component to most vaginal tumors. The overwhelming majority of females that develop tumors in the vagina are unspayed, however tumors that do occur in spayed females have a higher incidence of being malignant. The exception to that rule in this group are the canine transmissible venereal tumors (CTVT). These tumors are actually a contagious canine cancer. It is transmissible by direct contact such as the type that is made during mating, licking or rough play. Generally, your canine’s immune system would recognize and eliminate cells from an outside source such as this, however when CTVT cells are introduced a state of rapid growth of the cancer cells begins and will last between three and nine months. Although CTVT is found in moist of the world, it is more prevalent in tropical and subtropical urban environments.
Diagnosis of Tumors of the Vagina in Dogs
Initially, your veterinarian will need to get a full medical history of your pet as well as perform a physical examination, including a close examination of the tumors and the area surrounding them. A tissue sample will also be obtained so that it can be examined microscopically, as well as samples of any discharge from the vagina. A complete blood count, biochemistry profile, and urinalysis will also be requested to reveal any underlying or concurrent medical issues. Most of these growths are fairly simple to identify once the sample is viewed microscopically. To determine if there are other tumors your veterinarian may choose to perform a vaginoscopy. X-ray, ultrasound, or CT scans or may be used to ascertain if any tumors have spread further, and further analysis may be done in the lab to get more information from the tissue sample. If metastasis is suspected, your veterinarian may want to biopsy the local lymph nodes as well.
Treatment of Tumors of the Vagina in Dogs
Ovariohysterectomy, the surgical removal of the uterus and ovaries, is the treatment of choice in these cases, as well as the removal of the tumor itself. This generally reduces the risk of more tumors forming due to hormonal means as well as allowing for the examination of the abdominal organs to check more clearly for metastasis. Surgery is completely curative for a majority of benign vaginal tumors as they should not spread and most are only locally invasive.
Malignant tumors of any type in this area will be treated aggressively. A radical vulvovaginectomy or perineal urethrostomy will be done to remove all possible cancerous tissue. Once the surgeon has removed all that he or she physically can, radiation and chemotherapy will be utilized in an attempt to destroy any new or hidden cancer cells as well as to prevent recurrence. Dogs are more tolerant of chemotherapy than most humans and only around 5% need hospitalization from the treatment itself. Although there is less reported hair loss in dogs than in people some breeds (English Sheepdog, Lhasa Apso, Maltese, Schnauzer, Shih Tzu, and Poodle) are more prone to hair loss than others. 
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Recovery of Tumors of the Vagina in Dogs
Complications from chemotherapy can arise, so your veterinarian will probably want to do regular checks on your dog’s liver and kidney enzyme levels. Pets are often sent home the same day after chemotherapy, and although most of the drug is metabolized within just a few hours, some remnants of it can remain in the blood for a few days. It is important to use gloves when dealing with bodily fluids and maintain good hand washing hygiene. Children, pregnant and nursing women and immunocompromised adults should avoid contact with the bodily fluids during that time. Your pet should be monitored closely for additional tumors during and after their chemotherapy treatments.
Tumors of the Vagina Average Cost
From 40 quotes ranging from $3,000 - $15,000
Average Cost
$7,500
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Tumors of the Vagina Questions and Advice from Veterinary Professionals
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mix
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Eight Years
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17 found this helpful

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17 found this helpful

My pet has the following symptoms:
Fostering a dog who had babies in April and then spayed in October . She is about 7 years old . 2 lumps soft to touch near vagina
Dec. 18, 2020
Answered by Dr. Linda S. MVB MRCVS
17 Recommendations
Those growths aren't normal anatomy and should be examined by a vet. They may take a sample for analysis. Potential causes include cysts, fatty lumps, blocked glands, a tumour etc. If she has been licking or chewing at them, protect them by using a buster collar to prevent infection.
Dec. 29, 2020
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Labrador Retriever
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1 Year
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1 found this helpful

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1 found this helpful

My pet has the following symptoms:
Lump
Found this lump on our female puppy Tilly. Wondering what it is.
Sept. 29, 2020
Answered by Dr. Michele K. DVM
1 Recommendations
Thank you for your question. That lump appears to be a nipple, but without a frame of reference as far as location, it is difficult to say for sure. If you are concerned, it would be best to ask your veterinarian, as they can see the lump, where it is, and let you know if there is anything to worry about. I hope that all goes well for Tilly!
Sept. 30, 2020
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Siberian Husky
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dog-age-icon
Four Years
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4 found this helpful

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4 found this helpful

My pet has the following symptoms:
Lump On Valvula
Bleeding lump on my dogs bottom area makes her uncomfortable to use the restroom and do long walks
Sept. 26, 2020
Answered by Dr. Michele K. DVM
4 Recommendations
Thank you for your question. I apologize for the delay, this venue is not set up for urgent emails. That lump may need medication or to be removed. It would be best to have your pet seen by a veterinarian, as they can examine them, see what might be going on, and get treatment for them.
Oct. 15, 2020
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Toy chihuahua
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Twelve Years
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4 found this helpful

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4 found this helpful

My pet has the following symptoms:
Diarrhea
Kiki has thrown up and had bloodyish diarrhea 3 times each today. She has been drinking water and has an appetite. I noticed a hard black spot above her vagina which has never been there before.
Aug. 7, 2020
Answered by Dr. Michele K. DVM
4 Recommendations
Thank you for your question. From your picture, it seems that Kiki is not spayed, and intact female dogs can have more problems with cancer then spayed dogs. If the lump is new and you haven't noticed it there before, it would be best have her seen by a veterinarian as soon as possible. They can also see why she may be vomiting and having diarrhea, and see if the two things are related or not. I hope that all goes well for her.
Aug. 8, 2020
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dog-breed-icon
toy chihuahua
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dog-age-icon
Twelve Years
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1 found this helpful

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1 found this helpful

My pet has the following symptoms:
Diarrhea
Kiki has vomited 3 times and had bloody ish diarrhea 3 times in the past 12 hours. I just noticed a hard black mole looking spot above her vagina and it has never been there before.
Aug. 7, 2020
Answered by Dr. Michele K. DVM
1 Recommendations
Thank you for your question. From your picture, it seems that Kiki is not spayed, and intact female dogs can have more problems with cancer then spayed dogs. If the lump is new and you haven't noticed it there before, it would be best have her seen by a veterinarian as soon as possible. They can also see why she may be vomiting and having diarrhea, and see if the two things are related or not. I hope that all goes well for her.
Aug. 8, 2020
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Maltipoo
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Binky
dog-age-icon
14 Years
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0 found this helpful

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0 found this helpful

My pet has the following symptoms:
Vaginal Bleeding
Binky started with blood showing in urine. It has progressed to more blood coming from vulva.. she drips blood and has to wear a diaper. She is still eating, drinking water, moving around. She is urinating and taking poops. She is not spayed. Could she have a tumor? What can I do to help her?
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Yorkie
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Isabella
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12 Days
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0 found this helpful

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My 12 year old female Yorkie was diagnosed with Leiomyosarcoma after a mass in her vagina popped out. We took her in for emergency surgery in November of 2018 where the vets removed the mass and sent it out and it came back her results. Her metastasis says 3 on the paperwork. What does this mean? Before knowing about the tumor she had blood in her urine often which we thought was the cause of a UTI, the medications would work on and off but then we found out the cause of all of this was from the tumor. Just two days ago I noted a few drops of light colors blood in her urine. What can be done to stop the light bleeding? Is this the cause of the light spotty bleeding from a re-growing of the same tumor?
Tumors of the Vagina Average Cost
From 40 quotes ranging from $3,000 - $15,000
Average Cost
$7,500
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