Enlarged Spleen Average Cost

From 558 quotes ranging from $200 - 2,000

Average Cost


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What is Enlarged Spleen?

The spleen is an elongated organ that is on the left side of the stomach in cats. Though the organ isn't essential for living, an enlarged spleen may be a symptom of a more serious or chronic disease that will need veterinary care.

Splenomegaly, or an enlarged spleen, is a symptom of another condition or disease. The enlargement is due to inflammation, which occurs due to infiltration of abnormal cells as a result of the primary condition. The primary condition that is causing the enlargement is typically related to the function of the spleen, such as filtering blood or synthesizing antibodies in the cat's body. The cat's spleen may either enlarge uniformly over the entire organ or enlarge asymmetrically.

Symptoms of Enlarged Spleen in Cats

Because the spleen is responsible for storing and filtering blood, removing old cells and foreign bodies from the bloodstream, and helping the immune system function properly, the cat may experience a variety of symptoms that warrant investigation in order to treat the primary cause of the enlargement. 

  • Lack of appetite
  • Weight loss
  • Enlarged lymph nodes
  • Swollen abdomen
  • Diarrhea
  • Vomiting
  • Abdominal pain/sensitivity
  • Lethargy
  • Weakness
  • Fainting

Causes of Enlarged Spleen in Cats

There are a variety of causes of splenomegaly in cats, which include: 

  • Abdominal injury due to trauma
  • Heart failure
  • Heartworms
  • Inflammatory bowel disease
  • Infectious disorders, such as feline infectious peritonitis
  • Cancer, such as multiple myeloma and feline leukemia virus
  • Bacterial infection
  • Autoimmune disorders, such as systemic lupus
  • Splenic torsion (rotation or twisting of the spleen)
  • Fungal infections, such as histoplasmosis

Diagnosis of Enlarged Spleen in Cats

The veterinarian will examine the cat, feeling for swollen lymph nodes and a swollen abdomen. In some cases, the enlarged spleen will be protruding through the abdominal skin and is noticeable with a visual examination. The veterinarian will need to know the cat's complete health history, all of the symptoms the cat is experiencing, and when symptoms first began.

A complete blood count, biochemical blood profile and a urinalysis will be taken. These tests will help the veterinarian determine the primary condition that is causing the spleen enlargement. The tests will also show how the other organs, such as the kidneys and liver, are being affected by the primary condition. The blood tests will typically also show signs of an enlarged spleen, which include a high white blood cell count, low hemoglobin levels (anemia) and abnormal cells that are causing the inflammation.

Diagnostic tests, such as an x-ray and ultrasound, will be performed. These tests will allow the veterinarian to view the spleen and the surrounding organs for any abnormalities. A fine needle aspiration may also be performed. During this test, the veterinarian will insert a thin needle into the spleen, drawing out a fluid sample for further analysis. In rare occasions, exploratory surgery may be necessary if a diagnosis isn't found with other tests.

Treatment of Enlarged Spleen in Cats

Treatment of the enlarged spleen will depend on treating the primary condition that is causing the inflammation.


Corticosteroids may be prescribed by the veterinarian in order to reduce the inflammation in the spleen and other organs. If the enlargement is due to a bacterial infection, antibiotics will be prescribed. Autoimmune primary causes will be treated with immunosuppressants, which work to suppress the reaction of the immune system. Cancer may be treated with chemotherapy, which will work to kill the cancer cells in the cat's body. Cats who are severely anemic may need to take iron supplements. Medications to treat fungal infections may also be prescribed.


In cases of splenic torsion or trauma, the veterinarian may need to remove all or part of the cat's spleen (splenectomy). This will be done in the hospital under general anesthesia. During surgery, the veterinarian will make a small incision in the cat's abdomen. The entire spleen or affected portion of the spleen will be removed and the blood vessels attached to the spleen will be clamped and tied. The incision site will then be closed. Surgery may also be necessary to remove any tumors or masses that have formed due to cancer.

Recovery of Enlarged Spleen in Cats

The cat will need to continue to take medication as prescribed by the veterinarian in order to prevent the primary condition from worsening and causing the spleen to enlarge once more. Follow-up appointments to monitor labs and medication will be necessary. If the cat had surgery, it's important to care for the incision site at home to prevent infection from occurring. Keeping the cat calm and stopping strenuous activities is essential in proper recovery.

Enlarged Spleen Questions and Advice from Veterinary Professionals

16 Years
Moderate condition
0 found helpful
Moderate condition

Has Symptoms

Not eati

15 year old cat stopped eating. Went to vet first for a blood test- which showed nothing- then an xray. They are suggesting a sonogram because they think there is a mass or enlarged splean pushing some of the other organs outword. My cat has always had vomiting issues and has had tests done in the past that show nothing. She also has an overactive thyroid. Vet gave her fluid and anti nausia medication and now Shell eat if i feed her but has difficulty on her own. Since nothing showing in her blood- what coykd it be

Dr. Michele King, DVM
Dr. Michele King, DVM
1059 Recommendations
It is difficult to say what might be going on with Cayanne without further testing. The ultrasound would be a good idea to look for any abnormalities that may be causing her decreased appetite. I hope that she is okay.

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Maine Coon
16 Years
Mild condition
0 found helpful
Mild condition

Has Symptoms

No apparent symptoms

I have a 16 year old cat who's been diagnosed with splenomegaly. In addition to this recent diagnosis, he was also recently diagnosed with diabetes mellitus, stage one chronic renal failure and is now developing congestive heart failure along with a mass that has developed in his liver within the last month. The initial intent was to have his spleen removed; but his vet has mentioned that given these other conditions, my cat's health could potentially crash after the surgery. My question is if there's alternate treatments that can be done to treat or reduce my cat's splenomegaly.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2479 Recommendations
There is no universal treatment for splenomegaly as it is a symptom not a condition itself, something else causes the spleen to enlarge. Infections, autoimmune diseases, tumours, torsion, heart failure among other causes may lead to splenomegaly; therefore any treatment should be directed at the primary condition and not specifically at the spleen. Regards Dr Callum Turner DVM

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Maine Coon
11 Years
Moderate condition
0 found helpful
Moderate condition

Has Symptoms


Cat seems to hack/cough like a hairball is coming, but nothing comes. It's random. Just started after we moved to another state (also near a coal plant). Vet gave hairball medication but hasn't worked. She crackles/wheezes afterward. She crouches and stretches her neck out and twists her head to the side when she does the coughs. Vet said her lungs sound clear. He said X-ray of lungs look fine, but online it said I shouldn't see branches in her lungs (I see very faint gray lines). The rest of her lungs are black (air). What could this be? He didn't say anything about her heart and just chalked it up to an allergy (because she wasn't coughing there at the clinic). I said it was random times but he dismissed it. I'm afraid it could be asthma.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2479 Recommendations

On an x-ray you will still see faint grey lines as the trachea, bronchi etc… of the lungs are made up of tissue which partially block the x-rays passing through them, bones block all of the x-rays and air blocks nothing (the film starts clear and the x-rays turn the areas black). There are many different causes for hacking cough including allergies, chemical irritation, heart failure, laryngeal problems etc… If you are still concerned, you may visit another Veterinarian for an examination; ask your original Veterinarian for a copy of the x-ray (so you don’t need to pay again). Regards Dr Callum Turner DVM

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long haired gray
16 Years
Critical condition
0 found helpful
Critical condition

Has Symptoms

Loud Breathing

Major swollen belly.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
2479 Recommendations

A major swollen belly in a cat (especially geriatric cats) is more likely to be caused by fluid in the abdomen (ascites), which would also cause lethargy, weakness and breathing difficulties (either from fluid in the lungs, pressure of fluid against diaphragm or both). Causes may be due to liver damage, infection, inflammation, low blood protein or tumours. You would need to take Precious to your Veterinarian for examination and blood tests (as well as possibly x-rays) to help determine the cause and possible treatment. Regards Dr Callum Turner DVM

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3 Years
Has Symptoms
Pale Mucous Membranes
Meowing Looking At Me , Hiding Her Head Wont Let M
Out Of Breath
My 3 yr old female spayed cat used the potty on our wood floors, which she never does. Then she started meowing a lot and panting. From watching Dr. Pol, I look at the inside of her eyelids and they were white. I knew something was wrong. Took her to the Vet at 4pm, her gums were completely white. She ate that day, slept on my bed as usual and ate food. They did an xray and said her spleen was enlarged, looked like a little fluid in the lungs and her temp. had dropped to 92. They put her on fluids and in the oxygen tank. Because they did not have over night care I took her home and was going to bring her back in the morning for surgery, I could have taken her to an emergency vet to take care of her but I was hoping if I kept her warm she would make it till morning so I could take her back to the low cost vet. By 12:45 she passed away with me sitting next to her and holding her. There were no signs and within hours she was gone. We are still in shock and heartbroken. I have had to take one of my pet into the vet for each month for the last four months. My 15 yr old cat passed from Kidney failure, My cat Mickey, had a wide gash and needed stitches, then my dog had a mammory lump removed and now my Minnie is gone.
10 Years
Has Symptoms
Swollen Abdomen
Jackie developed a swollen abdomen although he did not oshow any other signs of illness. He had an X-ray, a blood test and an ultra scan. The blood test showed slight anaemia and the ultra scan displayed an enlarged spleen. The vet thought he must have cancer and prescribed steroids. However his main problem as well as the swollen abdomen is his teeth and he has had three courses of antibiotics since March. Could his teeth contribute to his swollen abdomen as he eats well, doesn't have a fever, does not vomit, and except when he was on steroids has a normal bowel movement. When he was on steroids, his movement was black so we ran the steroids down. Any advice from anyone would be very much appreciated. Jack is a rescued Siamese, about 10 years' old and found inside a car engine.