Paw Inflammation in Cats
Written By hannah hollinger
Published: 10/15/2016Updated: 09/16/2021
Veterinary reviewed by Michele K.
Paw Inflammation in Cats - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Paw Inflammation?
Presently, no predispositions for plasma cell pododermatitis have been identified in regards to breed, sex, or age. It is likely that this condition occurs on a seasonal basis, but this has not yet been proven.
Inflammation of the paws in cats – also known by its technical name, plasma cell pododermatitis (FPP) – is a condition which causes the pads of the paws to swell. This can affect one pad or multiple pads at a time. This condition is somewhat rare in cats, and little is known about what causes it. However, it has been shown to recur in many cases.
Youtube Play
Paw Inflammation Average Cost
From 552 quotes ranging from $200 - $1,000
Average Cost
$400
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Symptoms of Paw Inflammation in Cats
While plasma cell pododermatitis is generally not life-threatening, you’ll want to ensure that you take your cat to the vet as soon as you notice any of the following symptoms in order to reduce their pain and prevent the condition from progressing.
  • Signs of pain when walking
  • Lameness
  • Red, inflamed, and/or swollen skin around the paws
  • Blisters or draining sores
  • Excessive grooming of the paws
Causes of Paw Inflammation in Cats
Due to the rarity of the condition,  little information is known about the causes of plasma cell pododermatitis. One suspected cause is a hyperactive immune system, particularly in the paw tissues. Presently, this is the most plausible cause. In one study, half of the cats that participated were also diagnosed with feline immunodeficiency virus, though there is not enough evidence to suggest causation. A single infectious cause has not been identified.
In a select few cases, FPP was symptomatic rather than a standalone condition. Additionally, FPP has been observed more frequently in the spring and summer; however, there is not enough evidence to show that this condition has a seasonal cause. Trauma, allergic reaction, and exposure to certain chemicals may be causes of FPP.
Diagnosis of Paw Inflammation in Cats
The vet will make a tentative diagnosis based on the appearance of the paws and presentation of symptoms. They will likely ask you about your cat’s medical history in addition to their indoor and outdoor activity. You should inform your vet if you suspect your cat has been exposed to any kinds of chemicals or experienced any recent trauma that may have caused FPP.
The vet will make a more definitive diagnosis through taking a biopsy of the paw tissue. A bacterial culture may also be taken. The bacterial culture will assist your vet in deciding which antibiotic is best to use for treatment in the event that a bacterial infection is present. If there is fluid or blood in the sores or blisters, your vet may use a microscope to examine it.
Treatment of Paw Inflammation in Cats
Treatment of the condition will depend on what the underlying cause is. If a bacterial infection or allergic reaction has been identified, antibiotics will usually be administered, typically for six to eight weeks. If the immune system is hyperactive, your vet will likely prescribe immunosuppressant drugs. If no cause can be identified, your vet may prescribe an antiseptic solution in which to soak your cat’s affected feet. This can promote healing of the tissue and soothe sore paws.
Though very rare, surgery may be required for extreme cases. These cases of FPP are usually caused by a foreign body or a more serious condition in which FPP is symptomatic.
In some cases, FPP has been shown to clear up on its own within two to three months. However, delaying or denying treatment based on this fact is unwise, as FPP may be caused by a number of different factors. This condition is often painful for the cat, and treatment will help to reduce pain as well as manage the underlying cause.
Petted logo

Worried about the cost of treating your pet's symptoms?

Pet Insurance covers the cost of many common pet health conditions. Prepare for the unexpected by getting a quote from top pet insurance providers.

Get a quote

background
Recovery of Paw Inflammation in Cats
During the recovery period, don’t allow your cat into areas where they may cause trauma to the feet. This includes gardens or other outdoor areas that utilize pesticides or fertilizer. Ensure that all cleaning products are kept out of your cat’s reach.
It is important that you continue to administer any antibiotics prescribed to your cat for the entire recommended duration of treatment, even if the condition starts to improve. Failure to do so could result in aggressive recurrence. If your vet has prescribed an antiseptic soak, it is imperative that you use only this solution to soak their feet. Using different solutions made for animal or human use may cause burns on the pads of the paw and worsen the condition.
If sores or blisters are present, your vet will likely schedule a follow-up appointment in order to monitor them until they have healed. If the condition recurs, contact your vet immediately to seek treatment. Your vet will help you devise a treatment plan based on your cat’s specific needs.
Paw Inflammation Average Cost
From 552 quotes ranging from $200 - $1,000
Average Cost
$400
arrow-up-icon
Top
Paw Inflammation Questions and Advice from Veterinary Professionals
dog-breed-icon
Catahoula Cur
dog-name-icon
dog-age-icon
Six Years
thumbs-up-icon

11 found this helpful

thumbs-up-icon

11 found this helpful

My pet has the following symptoms:
Swollen Paw
My cat was outside 2 days ago and came back w swollen paw. There's no cuts or bites. She won't put much weight on it. It is not warm to the touch. She is eating and seems stable. What is wrong?
July 28, 2020
Answered by Dr. Michele K. DVM
11 Recommendations
Thank you for your question. There are so many things that can happen to outdoor cats, it is difficult to say what might be wrong without seeing her It could be an abscess, a strain or sprain, or a fracture. If she is not putting weight on it and it isn't improving over 2 days, it would be best to have her seen by a veterinarian. They can examine her, see what might be going on, and get treatment for her so that it gets better. Until she is back to her normal self, it would be best to keep her inside, as well. I hope that all goes well for her!
July 28, 2020
Was this question and answer helpful?
dog-breed-icon
Calico
dog-name-icon
Sir Fluffy
dog-age-icon
1 Year
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Limping
Swollen
No Pressure
Cat was laying on ironing board, asleep. He fell off and the board fell on his foot. Now his paw is swollen and warm. He can't really put pressure on it, his foot is up a lot, and he limps. On another note, he still jumps onto the table, chairs, etc. Is it broken, or can I just splint it and put him on rest for a while?
Sept. 18, 2018
Was this question and answer helpful?
dog-breed-icon
Maine Coon
dog-name-icon
Baby
dog-age-icon
8 Years
thumbs-up-icon

7 found this helpful

thumbs-up-icon

7 found this helpful

My pet has the following symptoms:
Inflamed Paws
I took my cat into the vet on Monday. She can barely walk, all four paws are inflamed and her temp was slightly elevated. They gave her an antibiotic shot, and a steroid injection. It’s been over 48 hours, and I have seen no improvement. She can still barely walk, and I can tell she’s in pain. I plan on taking her back in tomorrow morning. I think she needs Doxycyline. Do you have any other suggestions? Her paws are definitely inflamed, and her temperature seems elevated still, her paws are very warm.
June 21, 2018
7 Recommendations
Without examining Baby I cannot say what the specific cause of the inflammation is, if your Veterinarian determines it is plasma cell pododermatitis (or similar) then they may prescribe doxycycline (with or without prednisone). For now, keep Baby comfortable and visit your Veterinarian in the morning. Regards Dr Callum Turner DVM
June 21, 2018
Was this question and answer helpful?
dog-breed-icon
American Sh
dog-name-icon
Izaan
dog-age-icon
1 Year
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Swelling
Hello, my cat yesterday had a swollen front right paw. He likes to run outside frequently when we open the door and this time something must have happened which cause his paw to swell. I noticed it a couple of hours later and took him to the vet. The vet gave him a benedryl shot just for any allergic reaction as well as another shot. These two shots are named Dexamethasone and Diphenhydramine. He came home and was foaming from the mouth, vomited, and was hyperventilating. He was very mad at the vet and irritated something I never saw of him. The vet probably thought it was because of the vet visit that caused the reaction when he came home. He stopped after a while. It’s the next day and he’s not himself still. Not playful and sitting still. I don’t know if this is a normal behavior after swelling.
June 16, 2018
0 Recommendations
The treatment given may cause some changes in behaviour short term as well as any pain or discomfort from the paw swelling itself. Foaming at the mouth may have been attributable to a drying of the mouth (side effect of treatment) making saliva sticky and increased respiration due to pain from the paw swelling. I would keep an eye on Izaan for the time being and visit your Veterinarian if there is no improvement or symptoms get worse. Regards Dr Callum Turner DVM
June 17, 2018
Was this question and answer helpful?
dog-breed-icon
house cat
dog-name-icon
Cat
dog-age-icon
5 Years
thumbs-up-icon

3 found this helpful

thumbs-up-icon

3 found this helpful

My pet has the following symptoms:
Swelling
Pain
Limping
My cat was outside for the day, she came back with a swollen hind paw. It has been two days and the swelling has increased. The lower portion of her leg is swollen as well. I’m not sure if this is an infection, a bug bite, a broken bone? She is favoring it and becomes aggressive if I touch it. She is definitely in pain, but I’m not sure of the cause. I didn’t notice any cuts or blood anywhere.
June 6, 2018
3 Recommendations
Without examining her I cannot determine whether it is a bite, traumatic injury or infection; sometimes there isn’t a visible puncture wound with some bites so they can be difficult to diagnose. You should take the cat to your Veterinarian for an examination to check for any orthopaedic injuries, determine the overall cause and to get her some pain relief; in the meantime restrict activity and allow plenty of rest. Regards Dr Callum Turner DVM
June 6, 2018
Was this question and answer helpful?
dog-breed-icon
long haired cat
dog-name-icon
Hermione
dog-age-icon
3 Years
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Swollen Paw
My cat has been dealing with something like this or it is this. Her paw is so big and it didn't seem like it bothered her until finally part of it opened up and thumb size puss came out. I'm so sad for her. She has been on medicine for months now. At one point I took Hermione to emergency clinic and they put a cone on her. I was mortified, all so she couldn't lick it. So I put her in a separate room so she couldn't jump and move to much and I went to my eye exam. When I came home from the eye exam, I couldn't see because my eyes were dilated but I could see the plumbers arrived and went in through the cellar to work. When I got inside, the door to that room was open. I went in to find the room empty. I looked in the basement and how hard can it be to find a cat with a cone when you can't see well? I looked for hours. I got so scared she got out through cellar door when plumbers came in and out. The plumbers promised she didn't get out but the cat has a cone on her and at this point I looked everywhere. My worst fear is she is outside with a cone that I allowed and she would die. Two hours later I realized i had not seen any cat, there are three, but one kept running up to me and disappearing so I followed her and my cat was stuck under a bed. I pulled her out and ripped off the cone. I loved her and promised that wouldn't happen again. Turns out she needs to lick it my vet said to keep puss that later came clean. Gross. One digit expressed and now her others are so big and she is limping, not putting any pressure on it. I keep it clean of litter because now litter clings to it like gum. She is the best cat because she is tolerant of the spa like cleaning where I massage it and try to get in the pads and clean it out. She is in pain now. She has a shot of antibiotics and taking one orally everyday. I keep praying she will be okay. I had a horrible dream she had that leg removed and I was playing/scratching her with the leg and she was so mad. I don't want that to happen. What else can I do? I'm her Dad btw, I found her my first month I moved to NEPA in the middle of the road, in the middle of the woods, in the snow and she was a hairless kitten with Herpes I found out, so she is compromised. She has a clone foot and is now the most beautiful, charming, well mannered cat. She needs to be around me constantly now. Anything else I can do?
Paw Inflammation Average Cost
From 552 quotes ranging from $200 - $1,000
Average Cost
$400
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Need pet insurance?
Need pet insurance?

Learn more in the Wag! app

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install


© 2025 Wag Labs, Inc. All rights reserved.


© 2025 Wag Labs, Inc. All rights reserved.