What is Color Dilution Alopecia?
Color dilution alopecia (CDA) is an inherited skin condition, and is more common in dogs that have been bred for a diluted coat color. For adult dogs with the inherited gene, it is also considered a form of follicular dysplasia. It is more commonly found in dogs with a fawn or blue coat. These two coat colors have been diluted from reds, browns, blacks, and tans.
Alopecia is a disorder that causes complete and permanent hair loss, resulting in a patchy appearance. It affects the hair follicle at the level below your dog’s skin, causing it to self-destruct, making new hair growth impossible. Hypotrichosis can be confused with alopecia, as it is much more common, although this condition results in less than normal hair, and not total loss of hair coat.
Color dilution alopecia (CDA) is an inherited genetic condition that causes patchy hair loss and skin problems, including scaliness, and itchy skin. It can also present recurring bacterial infections. Other than the cosmetic appearance of your dog, his health is not at risk.
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Symptoms of Color Dilution Alopecia in Dogs
- Hair loss - The first sign of color dilution alopecia is hair loss, though this will not appear until the dog is at least six months old and often up to three years of age
- Broken hairs, known as stubble alopecia - This can be scaling skin, papules (swollen bump not producing pus), and pustules (a small blister or pimple producing pus)
- Dry, flaky skin
- Recurring bacterial infections - This will usually be located on your dog’s back and can be identified by infected hair follicles, looking like tiny bumps
- An infection could also bring with it pruritus (severe itching)
Color Dilution Alopecia (CDA) can affect many breeds, although it may affect only certain individual dogs within those breeds. These individual dogs are recognized by the color of their noses, eye rims, and lips. They may be flesh colored, lavender, blue-gray, or blue. Their coat colors can range from taupe, fawn, blue, blue-fawn, or bronze, although they will always be able to be distinguished from their non-diluted counterparts. Breeds commonly affected by this recessive gene condition are:
- Doberman Pinscher
- Chow Chow
- Great Dane
- Standard Poodle
- Irish Setter
- Yorkshire Terrier
- Italian Greyhound
- Bernese Mountain Dog
- Shetland Sheepdog
- Boston Terrier
- German Shepherd
Causes of Color Dilution Alopecia in Dogs
- The most significant cause for color dilution alopecia is inheritance, although dogs that are affected by the recessive gene will be born with a healthy looking coat
- There is some thinking that the amount of dilution in the dog will translate into the severity of the alopecia
- The D-Locus gene controls the vibrancy of your dog’s coat color
- A non-diluted dog will have normal coloring with either a Dd gene, or DD gene
- Diluted dogs will have a dd gene, evident by your dog’s nose color
- Because dilution is a recessive gene, only dogs carrying the DD gene can be affected, though a dog in possession of the Dd gene will be a carrier
- As the cause for color dilution alopecia is not completely understood, it is thought to occur when fractured hair releases it's formation of coloring which is deadly to the hair follicles
Diagnosis of Color Dilution Alopecia in Dogs
As a pet owner you may notice changes in your dog’s coat. If you see his fur becoming brittle, broken, or rough, call your veterinarian. If your pet has recurring bacterial infections, discuss this with the veterinary team as part of the diagnosis.
The veterinarian may order a trichogram, which is a microscopic evaluation of your dog’s hair, in order to reveal any large grains of melanin or problems in the hair shaft and follicle. A dermatohistopathology test shows the veterinary team whether there are any hair follicles that may be filled with cystic keratin. It also reveals any clumps of melanin that may be hidden in the deepest layer of cells of the epidermis, and in the shaft and follicle of the hair.
If your veterinarian feels it is necessary to order further diagnostic tests or monitoring, she may choose to obtain a skin sample using local anesthetic. The skin will then be sent to a veterinary pathologist to show if there have been any changes in the condition. Your veterinary caregiver may test for skin mites to ensure this is not the cause for hair loss. In addition, because color dilution alopecia can mimic hormone related hair loss, your veterinarian may test for a healthy functioning thyroid.
Treatment of Color Dilution Alopecia in Dogs
There is no cure for color dilution alopecia as it is a genetic predisposition within your dog. Your veterinarian can treat the symptoms related to color dilution alopecia; it is recommended to consult your veterinarian for advice, before attempting any treatments on your own.
- Topical ointments
- Moisturizing rinses
- Essential fatty acids
- Vitamin A
Shampoos, ointments, and rinses can be used to help relieve the scaly, dry, itchy skin your dog may be suffering from. Antibiotics may be prescribed to treat any bacterial infections that may occur. Remember to always finish the prescribed medication. Do not discontinue medication at the first sign of relief as it can allow the infection to become stronger next time and possibly become antibiotic resistant.
Some veterinarians may suggest a high dose of essential fatty acids and a vitamin A supplement. Before trying any homeopathic relief, be sure to consult with the veterinary team to make sure there won’t be any adverse effects or contraindications to concurrent therapy.
Recovery of Color Dilution Alopecia in Dogs
Managing the scaliness, infections, and dry skin will be key to the recovery of your canine companion. Do not use human hair loss remedies, as they can be harmful to your dog’s health. Products such as Rogaine can be dangerous, resulting in adverse side effects ranging from:
- Cardiac disease
Color dilution alopecia can be managed and bypassed by not breeding dogs known to have the color dilution; this includes dogs that are not only directly affected by the “dd” gene, but also their littermates and parents.
Color Dilution Alopecia Questions and Advice from Veterinary Professionals
My dog was diagnosed by a pet dermatologist with CDA (Color Dilution Alopecia). He is currently on fish oil and melatonin supplements. His shedding has been EXTREMELY out of control for a long time and is getting even worse. There are literally no words to describe how bad it is. Is this because of the CDA or could there be a separate issue going on?
Thank you Dr. King!
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I think my dog has color dilution alopecia.is it painful for him.
Colour dilution alopecia isn’t painful, but secondary infections may cause pain and itching; other conditions may cause hair loss and itching including allergies, parasites, other infections and hormonal conditions. A visit to your Veterinarian to confirm would be best. Regards Dr Callum Turner DVM
My little Chihuahua mix is a blue with CDA. I basically had to tell my vet what CDA was after several vet visits because she missed the symptoms. My problem is a constant re-occurrence of bacterial infection which comes back a few weeks after finishing a 2 week regimen of Clavamax. We initially tried a less strong antibiotic to no avail. Is there anything we can do to prevent reinfections? We've been giving him daily melatonin and Ultra EFA (Essential Fatty Acid Formulation).
I have a Chiweagle or Cheaglehund. She is all blue except for a small white blaise on her chest. When she was about 8 or 9 months old she lost all her hair except that white patch. She developed what I would call pimples on her back along with corse hairs. A few months later she started growing this really fine velvety puppy like hair all over but with the course hairs still on her back but not many. She still gets the pimple things in that area sometimes too. The white patch has always remained like normal hair and does not shed. I give her vitamins and coat supplements but don't really know what caused the hair loss and regrowth as that was before the vitamins. It's really weird and we've gotten many comments about her appearance. Strangest dog ever.
This question is for Jen where can I get these products at
My Pittie was just diagnosed with CDA. The diagnosis was made through biopsy of the affected areas of hair loss, by an animal dermatologist.
She first did a thyroid test because as she explained, low thyroid can cause hair loss.When the thyroid was negative, the biopsy was done.
Both my local vet and the dermatology vet explained that there is no evidence of food allergy or other condition, so no food changes needed to be made. I am sorry to hear that 3 different vets were not able to diagnose the condition in your Lab. we are finding that if we do not get help from our local vet, we go straight for the specialists. Yes, it is costly, but we feel it is in the best interest of our fur babies to do so. Understandably, not everyone can afford to go this route.
I am interested in how much Omega and Biotin you gave your baby, and what the melatonin contributed to the process.
How long did it take for hair to begin to regrow?
Thank you for sharing your information.
Please share what is in the herbal antioxidant that you use.
Please share what is in the herbal antioxidant bath that you use.
I have a Dachshund, he is now 4 years old, he was a birthday gift from my parents. I first noticed his hair thinning when he was 8 months old, at his last "puppies wellness check" I shared my concerns with the vet, vet said , "some dogs just experience hairless as they age". I have developed a natural home remedies for his condition, Omega 3, Coconut Oil, unrefined, a herbal antioxidant bath every other week
Could you please tell me if there are any legitimate Colour Dilution Alopecia DNA tests that you know of in the world or if any such tests have ever been peer reviewed?
I do know that there are proven dilute tests, but is there actually a DNA test available to detect Colour Dilution Alopecia itself ?
thankyou and regards,
I also want to know the answer to Marie's question. Is there a DNA test that can detect it before we see symptoms? I have a liver GSD who is a year old. So far, his coat is still luxurious. He was carefully created so I expect him to hold up well.
We have a silver lab with this condition. I’m told they are bred from chocolate labs to get this diluted color. This particular lab was born from a silver mom and a silver lab instead. Her condition started around two years old. She was completely bald except for a small amount along her spine, the tip of her tail, her head and legs from about the knees down. I’ve taken her to three different vets and no one will believe me that she has CDA because I found my information on the internet. They have told me she has allergies and want to shoot her up with steroids and cortisone shots. They tested her thyroid and her blood sugar. They want me to change her food eight times a year. So I started her on my own home remedies. She’s around 70 pounds. She takes 3mg melatonin in the morning and 3mg at night. Two hair, skin and nails vitamins and two Omega 3, 6 and 9 supplements. Her hair completely grew back. The hair did not however grow back as normal grownup dog hair. It is puppy hair. Like microfiber. No more skin infections.
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