Exocrine Pancreatic Insufficiency in Dogs
Exocrine Pancreatic Insufficiency in Dogs - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Exocrine Pancreatic Insufficiency?
The condition EPI is best explained as a lack or absence of vital enzymes in your dog’s digestive system that would usually break down the food eaten into small enough pieces to allow smooth digestion. Without these vital enzymes, the food is not broken down small enough to be absorbed through the intestinal wall. As a result, the undigested food is excreted in the feces and your dog literally starves. Even though your dog may be constantly eating, he is getting no nourishment at all from the food.
Due to the lack of cellular functioning within the pancreas to produce enzymes to break down your dog’s food for absorption, your dog risks starving. This condition is known as exocrine pancreatic insufficiency.
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Symptoms of Exocrine Pancreatic Insufficiency in Dogs
  • This condition causes digestive and stomach problems leading to intestinal overgrowth of bacteria 
  • Weight loss even though your dog seems to eating plenty or has an increased appetite
  • Coprophagia which is a condition which causes your dog to eat its own stool
  • Chronic diarrhea
  • Weight loss
  • Lethargy
  • Loud rumbling sounds from the stomach
  • Frequent bowel movements
  • Frequent gas 
Types  
  • Exocrine pancreatic insufficiency in your dog is a result of the pancreas’ failure to produce the digestive enzymes need for proper food digestion 
  • For digesting starches and sugars an enzyme called amylase is needed 
  • These enzymes are lipases which digest fats 
  • Proteases enzyme is needed for proteins
  • Without enough of these vital enzymes, your dog will starve as the food will pass through him without the vital nutrients being used as the enzymes break down the food in order for the nutrients to be absorbed
Causes of Exocrine Pancreatic Insufficiency in Dogs
The causes can be traced to several potential elements. 
  • Inflammation of the pancreas (chronic pancreatitis) is one common cause
  • At a young age (up to 2 years old) in some cases,the pancreas just stops producing cells and decreases functionality – the reason has not yet been determined as to why
  • While no one is really sure of the reason, it has been suggested that it is an inherited condition
  • It seems to be more common in large dog breeds such as German Shepherds
Diagnosis of Exocrine Pancreatic Insufficiency in Dogs
Diagnosis is hard to pin point for this condition. Often it takes up to 90% of the pancreas to be destroyed before this condition is diagnosed. If your dog is eating feverishly yet starting to look gaunt, their body and muscle tone is slack, and your dog has very loose, often cow-patty style stools, then those symptoms need to be heeded. Your veterinarian will examine your dog and there are a number of tests that he can do to determine the cause of your dog’s ill health. 
These tests include blood tests, chymotrypsin activity measurement, analysis of the digestive enzymes levels that are present in the feces, and analysis of the feces under a microscope. The most effective test is the blood test which will show the level of enzymes present in the blood and is the best way to diagnose this condition. While the cause of this disease or condition is not really understood, and there is no cure as such for this problem, there are treatment measures that will help to balance your dog’s digestion and return him to good health.
Treatment of Exocrine Pancreatic Insufficiency in Dogs
While there is no cure for this condition, there is help available to assist your pet to overcome this debilitating disease. Your veterinarian is your first port of call and he will assist you to treat your dog. Usually the treatment includes supplements of pancreatic enzymes that you can add to your dog’s food. These targeted supplements can be in a powder form or come in capsules or tablets. The enzymes will start to assist your dog to break down the food he eats to get the much-needed nutrients. 
Because of your dog’s condition, your specialist may change the dietary components for your dog. The digestive system has been under a lot of stress, so replacing the high fat diet to an easy to assimilate diet will allow healing to occur. A low fat and low fibre diet will help your dog to digest the food and an antibiotic will control the bacteria that has been thriving in the gut. As the treatment takes effect, you will notice a change in your dog’s behavior as he is now getting the nourishment he needs, and he will lose that almost desperate driven behavior to fill his dietary needs.
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Recovery of Exocrine Pancreatic Insufficiency in Dogs
Ongoing management of this condition is vital to the health of your dog. A diet that is easy to digest and yet provides sufficient nourishment is essential. Your veterinarian will advise of ongoing treatment, and will need to check your dog’s progress from time to time. Once the treatment is administered and has taken effect, your dog’s behavior will become calmer and quieter. As vital nutrients are finally getting into his system, your dog will lose that gaunt look and his body will fill out and look healthier.
The problems with loose stools and stomach grumbles will cease and your dog’s hair coat will soon recover from dry and brittle to a shiny healthy look. With your dog now getting nourishment, he will stop eating everything in sight. With your veterinarian checking your dog’s progress, and adjusting the supplements, life will return to normal for your canine friend.
Paying to treat EPI out of pocket can be a major financial burden. Fortunately, most pet insurance companies reimburse claims within 3 days, putting 90% of the bill back in your pocket. In the market for pet insurance? Compare leading pet insurance companies to find the right plan for your pet.
Exocrine Pancreatic Insufficiency Questions and Advice from Veterinary Professionals
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Yorkie
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Sofie
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8 yes
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I have a Yorkie 8 yrs old that developed this. It came on so fast! I did notice some cow pies here and there and times when she strained for a bm. She is the best dog, used to be full of life and something has happened. She doesn’t want to eat, has a problem with her back legs, like they are weak. She gives me no kisses, wants to just lay and sleep all day. I have to force feed her and thisvis day 4 like this. Do they jump out of this mode? Or can it change their disposition too? I need my Sofie back!
Nov. 9, 2017
1 Recommendations
Exocrine pancreatic insufficiency isn’t a curable condition but it is a manageable condition with dietary supplementation of pancreatic enzymes or the feeding of raw pancreas along with other therapy like antibiotics or cobalamin supplementation. Once a dog starts to regain their appetite and are consuming pancreatic enzymes or raw pancreas an improvement in symptoms should be seen. Each case is different and you should discuss Sofie’s case with her Veterinarian and explore cobalamin supplementation too if not already done. Regards Dr Callum Turner DVM www.msdvetmanual.com/digestive-system/the-exocrine-pancreas/exocrine-pancreatic-insufficiency-in-small-animals
Nov. 10, 2017
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German Shorthaired Pointer
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Mina
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2 Years
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0 found this helpful

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My pet has the following symptoms:
Blowing Up
Belching
Farting
I have a young GSP bitch who has just turned two. For about the past year or so after every meal she blows up and is very gassy (belching and farting) and is clearly uncomfortable. It seems to surpass in a few hours but I'm terrified that one day it wont and she will go into full on bloat. She is raw fed but I have tried various other diets in a bid to try and work out what is actually causing her to do this but I am failing miserably. She have only been like it for the last year or so and seem to actually be getting worse, where as it used to be every few days she'd do it now its after every meal. Having done a bit more research today im wondering whether it may be a pancreatic issue, could this be possible? Any help or advice very very much appreciated, very worried dog owner here!
Aug. 30, 2017
0 Recommendations
There are various reasons for bloating and gas accumulation in dogs which may include food ingredients, rapid eating (swallowing air when eating), rapid drinking (swallowing air when drinking), stress among other causes; endocrine pancreatic insufficiency may cause gas and some bloating but would normally present with other symptoms as well (weight loss, diarrhoea and change in faeces colour). Try feeding Mina from a bowel which restricts her access to food and water to slow her down if she is eating fast. From an ingredients point of view, even raw food diets may cause gas in some dogs so it is never a 100% easy fix solution. Regards Dr Callum Turner DVM
Aug. 30, 2017
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Pomeranian
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Bemtley
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3 Years
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0 found this helpful

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My pet has the following symptoms:
Pancreatitis
Vomiting doesnt eat lathargic
July 26, 2017
0 Recommendations
Has Bemtley been diagnosed with pancreatitis by your Veterinarian? The type of pancreatitis and the overall health status will have a bearing on treatment or management of the condition; sometimes the exclusion of food and water for a period of time will help to calm the pancreas or supplements to counteract the low production of digestive enzymes. Regards Dr Callum Turner DVM
July 26, 2017
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