The initial response for treating phlebitis is to remove the irritating stimulant (most likely an intravenous catheter) that caused the inflammation. Minor cases of phlebitis will usually heal spontaneously on their own while cases where inflammation has progressed may require antibiotics, topical treatment, and wound care.
Wound care involves topical physical therapy over the venipuncture site and aims to reduce inflammation, promote blood flow, and stimulate tissue repair. Common methods include moist compresses and hydrotherapy. Moist compresses should be warmed before application over the venipuncture site. Hydrotherapy is a popular mode of physical therapy to promote circulation and repair. Low level light therapy, also known as photobiomodulation, is also becoming increasingly common and works by activating stem cells for faster healing. These techniques have relatively low risk.
In cases where systemic infection is evident, antibiotic therapy will be required. Antibiotics may be oral or injectable, however topical antibacterial ointments over the venipuncture site are contraindicated as they do not adequately reduce infection and can contribute to the development of antibiotic-resistant bacteria. In cases of severe inflammation, anti-inflammatory medications may be used as well.
Blood volume replacement or fluid infusion may be required in order to avoid thromboembolism due to stagnant blood flow. Any new catheters that are placed will require proper care for the aseptic technique as well as continual monitoring for adequate blood flow, adverse reactions, and pain.