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Best Supplements for Dogs 2025
Written by Emily Bayne
Veterinary reviewed by:
Published: 01/07/2025, edited: 01/13/2025
The Wag! team conducts independent research and consults pet experts to curate our recommendations. This content is supported by our affiliate pet partners and we may receive a commission on the links provided.
We all want our canine companions to be as healthy as possible for as long as possible. So, it's only natural to look into supplements to start your pup off on the right paw, helping them stay in good shape as they age. But with so many supplements for dogs available, it can be tough to pick one that actually works.
If you need help navigating the supplement aisle, we're here to steer you in the right direction! From multivitamins to calming chews, read on to learn about some of the best supplements for dogs on the market!
Overview
Zesty Paws 8-in-1 Multivitamin Soft Chews
Best multivitamins for dogs
If you're looking for a full-spectrum multivitamin chew that your dog will actually enjoy, Zesty Paws could be the one. Zesty Paws products have been featured in many of our supplement guides, and for a good reason!
Zesty Paw products are formulated with the help of registered animal dietitians to ensure a quality product that meets their customer's needs. The formulation checks all our boxes for a quality multivitamin: probiotics, minerals, vitamins, glucosamine and chondroitin for joint support, as well as antioxidants to boost the immune system.
Available flavors:
- Chicken
- Peanut Butter
Available sizes:
- 10 count
- 50 count
- 90 count
- 180 count
Zesty Paws Multivitamins
Why Wag! loves Zesty Paws Multivitamins
- Tasty and packed with 20 vitamins, minerals, and probiotics
- Combines several supplements into one convenient chew
- Contains glucosamine and chondroitin for joint health
- The formulation includes fish oil from wild-caught Alaskan pollock
Considerations & concerns
- Some reviewers have expressed concern about product consistency, saying the chews in some bottles were powdery
What pet parents say about Zesty Paws Multivitamins
"I started purchasing these multivitamins when my lab turned 1. He had some skin dryness/itching which was the main reason I bought these, but of course joint support and other benefits are a plus! His skin is not as dry and his itching is gone 98% of the time! He also loves the flavor. He gets them every night before bed and is always drooling (literally) when I pull the jar out."
Read more reviews on Chewy.
Image sourced from Chewy. Copyright Zesty Paws.
Pet Honesty Calming & Anxiety Chews
Best calming supplement for dogs
Seeing your pup struggle with anxiety is tough. Luckily, Pet Honesty produces one of the best calming chews to help you canine chill out.
These chews are thoughtfully formulated to tackle restlessness, stomach upset, and agitation due to anxiety. They contain relaxing agents like valerian, chamomile, melatonin, and hemp, as well as L-theanine and L-Tryptophan to help with mood. It even has ginger to help with the nausea that can accompany travel and separation anxiety.
Keep in mind these are not intended to replace your dog's medication and may not be effective on severe anxiety. If your dog is on medication for anxiety already, you should check with your vet before giving your dog calming chews.
Pet Honesty Calming & Anxiety Chews
Why Wag! loves Pet Honesty Calming Chews
- Works for up to 7 hours, making it a solid choice for dogs with separation anxiety
- The quick-acting formula begins working within 30 mins to an hour
- Made without corn, wheat, and GMOs
- Can help reduce hyperactivity
Considerations & concerns
- Consult your vet before giving your dog these chews if they're already prescribed anxiety meds
- Not a good choice for dogs with grain allergies since oats are the leading ingredient
What pet parents say about Pet Honesty Calming Chews
"I'm not a huge review writer, but this has [really] positively affected my rescue's demeanor! He is almost 2.. [He is] STRONGLY bonded to my family and very hesitant of new people. This has helped tremendously! He's a hyper boy, and this has helped him remain focused and attentive during training sessions. I actually wasn't sure if they were working, and thought maybe he was just aging out of that crazy hyper puppy phase naturally, so we took him off them and a few weeks later he was a wild and crazy zoomie monster again. A few weeks back on, and we have our attentive little learner back!!! SO worth the [$40] every 90 days. He's about 40 pounds and we still give him 2 chews daily. Just honestly makes him act like a "normal" dog. Not a zombie.. still plays and gets excited but is MUCH more able to self regulate! Cannot recommend enough!!!!"
Read more reviews on Chewy.
Image sourced from Chewy. Copyright Pet Honesty.
Nutramax Cosequin Hip & Joint Capsules
Best joint supplement for dogs
Joint care is especially important for large breeds and seniors. Years of wear and tear and weight bearing can take quite a toll, leading to pain and mobility issues. One of the best ways to support your dog's joints is to start them on glucosamine and chondroitin.
Nutramax Laboratories is one of the most trusted brands of joint supplements for dogs and has been in business for over 30 years. These capsules contain 250 mg of glucosamine and 200 mg of chondroitin and can be given whole, wrapped in cheese, or opened up and sprinkled over wet food.
Available sizes:
- 30-count
- 60-count
- 120-count
Nutramax Cosequin Capsules
Why Wag! loves Nutramax Cosequin Capsules
- Contains a joint-nourishing blend of glucosamine, chondroitin, and manganese
- Starts to work within 4 to 6 weeks
- An affordable option, a 132-count bottle is under $30
Considerations & concerns
- Since these are capsules, it can be more difficult to give to dogs (especially dogs who aren't fooled by the age-old pill-in-the-cheese trick)
What pet parents say about Nutramax Cosequin Capsules
"I could tell my 14 year old wasn't as playful as he had been. We noticed a big difference in just 3 days of starting these! It makes my dog mom heart happy. He also tolerates the pill form with his pancreatitis, which is a big bonus[.]"
Read more reviews on Chewy.
Image sourced from Chewy. Copyright Nutramax Laboratories Inc.
Zesty Paws Senior 11-in-1 Multivitamin Soft Chews
Best senior supplement for dogs
Senior dogs can benefit from supplementation with many different vitamins and minerals, but there's no need to juggle multiple products with this all-in-one senior multivitamin.
Zesty Paws Senior Advanced 11-in-1 multivitamin formula is a complex formula designed to support your elderly pup's immune system, skin, joints, brain, and cardiovascular system. We love that it has psyllium - a type of dietary fiber - and live probiotics, both of which promote healthy digestion. If you're looking for a full-spectrum vitamin supplement to put the pep back in your senior's step, Zesty Paws has you covered.
Available flavors:
- Beef
- Chicken
Available sizes:
- 90-count
- 180-count
Zesty Paws Senior Multivitamins
Why Wag! loves Zesty Paws
- Much more affordable than buying the vitamins and minerals individually
- Has added fiber and probiotics to alleviate constipation and other digestive issues
- Antioxidants help boost the immune system
- Added glucosamine to help with joint mobility
- Can be broken in half for smaller dogs
Considerations & concerns
- This product has recently been reformulated and some reviewers are disappointed in the new recipe
- The chews can vary in size
What pet parents say about Zesty Paws
"I started giving this to my 12 year old pit bull about 3-4 months ago. I started cooking for her at the same time, she was so lethargic & just slept most of the day & didn't play with her toys or chase the ball anymore. After about a month we were at the park & she was running with her much younger brother, chasing him, I couldn't believe it. They are both on a real food diet with kibble & the multifunctional vitamins & I don't plan on stopping it. She has lost weight & is wagging her tail again & ready to go whenever I am, to see her happy again makes it all worth it."
Read more reviews on Petco.
Image sourced from Chewy. Copyright Zesty Paws.
Native Pet Omega-3 Skin & Coat Chews
Best skin and coat supplement for dogs
Skin and coat problems are super prevalent among our canien compadres. If your woofer is constantly scratching from allergies or their coat is starting to dull from age, Native Pet's Skin and Coat Chews are worth checking out.
These yummy morsels contain salmon oil, biotin, collagen, and fatty acids to put the shine back into your woofer's coat. These can also help with shedding and itching due to skin problems!
Native Pet Omega-3 Skin & Coat Chews
Why Wag! loves Native Pet
- High-quality, limited ingredient formula
- Free of artificial colors or preservatives
- Dogs go crazy for the yummy chicken flavor
- Reasonably priced
Considerations & concerns
- Some pet parents feel that these chews are too hard
What pet parents say about Native Pet
"I recently tried the Native Pet Skin & Coat Chews with Omega-3 Supplement for my dog, and I couldn't be happier with the results. Here's why I give this product a 5-star rating: Improved Coat Health After just a few weeks of using these chews, I noticed a significant improvement in the shine and softness of my dog's fur. The Omega-3s in the supplement seem to be doing wonders for his skin and coat health. Reduction in Shedding One of the most impressive benefits has been the noticeable reduction in shedding. My dog used to shed quite a bit, but now the amount of hair I find around the house has decreased significantly, making grooming and cleaning much easier. [As for] palatability and ease of use: my picky eater loves these chews, which makes administering the supplement a breeze. The chews are conveniently packaged and easy to give, requiring no mixing or mess."
Read more reviews on Chewy.
Image sourced from Chewy. Copyright Native Pet
FAQ
Do dog supplements actually work?
How often should I give my dog supplements?
How do glucosamine and chondroitin work?