Many times a female dog will not have a proper heat cycle until they are about two years of age. This is especially true in many large or giant breeds; they do not reach sexual maturity until they are two years old. You should be concerned if your female does not have a heat cycle by the time they are 24 to 30 months of age, and it would be a good idea to have your veterinarian examine her.
Silent Heat Cycle
This occurs when your female will have a heat cycle without the normal symptoms such as bleeding and swelling of the vulva. Females will still be receptive to males and can become pregnant. Your veterinarian can check for a silent heat cycle by performing vaginal cytology and progesterone assays.
Hypothyroidism
Your dog may be suffering from a thyroid problem that can cause irregular heat cycles and in more severe cases can cause your female to not cycle at all. Hypothyroidism is thought to be genetic and dogs diagnosed with it should not be bred.
Ovarian Hypoplasia
There are instances when the ovaries do not fully develop and are incapable of producing enough estrogen for your female to come into heat or have a normal heat cycle. The mammary glands and the vulva will stay small and look underdeveloped.
Malnutrition
Female dogs that are malnourished from poor diet or recent illness will many times not have a heat cycle. Feeding a low quality dog food that is low in protein and fat content can cause your female to not have a heat cycle. If you are planning on breeding your female, be sure to feed her a high quality food to ensure that her body is able produce enough estrogen for a proper heat cycle.
Tumor on the Ovaries
Tumors can develop for many different reasons, some being cancerous and some being benign. When a tumor develops on your female’s ovaries, this can inhibit heat cycles. Your veterinarian will need perform diagnostic testing to determine if a tumor is present and whether or not it is cancerous.