There are three main chemicals present in the umbrella tree that are responsible for the symptoms detailed above: insoluble oxalates, saponins and terpenoids. Insoluble oxalates are a solidified form of oxalic acid, taking the shape of tiny sharp crystals that dig into any tissues they come into contact with, causing large amounts of inflammation and discomfort. They are responsible for the irritation of the mouth and much of the vomiting and diarrhea. Saponins are a form of naturally occurring insecticide, which work by directly binding with and attacking cells and some neuro-transmitting enzymes. This worsens the vomiting, diarrhea, and irritation, as well as causing the problems with the dilation of the pupil. Terpenoids, meanwhile, are a class of general-purpose irritants that are produced by plants in order to make them unappealing to herbivorous animals.