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What is Adrenalectomy?

Adrenalectomy refers to the surgical removal of an adrenal gland, located just in front of the kidney. This procedure is challenging for several reasons and usually only undertaken in a specialist setting by expert surgeons. 

Indications for adrenalectomy include the presence of a tumor. The surgery is high-risk due to difficulty accessing the tumor and the high percentage of cases that throw fatal blood clots in the 24 hours post-surgery. However, those dogs that do survive often have a reasonable long term outlook.

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Adrenalectomy Procedure in Dogs

Adrenalectomy requires a full general anesthetic at a facility with the capability to provide rigorous monitoring of blood pressure, blood gases, ECG, and other vital parameters during anesthesia, plus an intensive care facility for the postoperative period. 

Depending on the type of adrenal tumor, the dog may receive medical therapy for two weeks prior to surgery in order to reduce the risk of complications such as throwing a life-threatening blood clot and to control high blood pressure. 

On the day of surgery, the dog should be fasting, and a premed injection is given which includes painkillers. After the dog is anesthetized, the surgeon usually makes on incision in the midline of the dog's belly, although an alternative technique involving an incision high on the right flank is preferred by some specialist when the right adrenal gland is to be removed. 

The surgeon uses retractors to hold the gut and liver aside, in order to gain access to the adrenal gland deep within the abdomen. The blood supply to the gland is tied off and the gland itself dissected away. 

The surgeon closes the laparotomy site and the patient is transferred to intensive care for close monitoring for 24 hours. 

Efficacy of Adrenalectomy in Dogs

The act of removing the adrenal gland is an efficacious for getting rid of tumors in this location. The ultimate success depends on whether or not the patient survives to leave the hospital, how invasive the tumor was, and if malignant spread has already taken place or not. 

The complication rate is high (again depending on the type of tumor) with blood clots to the lungs being a major source of death peri and post-operatively. Other complications include pancreatitis, kidney failure, pneumonia, and heart rhythm irregularities. 

If surgery is not an option then the clinician can try to control the clinical signs by the use of medication, but this is only palliative and rarely satisfactory.

Adrenalectomy Recovery in Dogs

The patient is at greatest risk during the operation itself and in the 24 hours post surgery. This is because rapid changes in hormone levels, plus the tendency for blood clots to form, can cause catastrophic, potentially fatal, problems that are difficult to control. 

As a rule of thumb, those that cope with this vital time and are able to go home, often do well provided that their cancer was no well advanced prior to surgery. It is essential to observe the regular guidelines during the recovery period, such as preventing the dog from licking the wound, rest, and avoiding stress. 

Medication started prior to surgery is gradually reduced and stopped, as indicated by regular blood pressure monitoring.

Skin sutures are usually removed at the 10 - 14 day point. 

Cost of Adrenalectomy in Dogs

The dog requires an extensive work up prior to adrenalectomy which includes screening blood tests, specific diagnostic blood tests, radiographs and ultrasound. These alone will run into many hundreds of dollars. 

The surgical procedure and the intensive care needed in the postoperative period are costly, and an owner should expect to pay thousands of dollars or more. 

Dog Adrenalectomy Considerations

Adrenalectomy is not a procedure to be taken on lightly. Whilst the procedure may be the dog's best option for recovery, the complication rate is high. It is therefore essential that each dog is thoroughly screened prior to going ahead, in order to determine that the cancer is not already far advanced. This would mean that the risks are unacceptable in view of the limited extra time the dog would gain should surgery go well. 

Adrenalectomy Prevention in Dogs

It is not thought that environmental factors play a part in the development of adrenal gland tumors, thus it is difficult for the conscientious owner who wishes to reduce their pet's risk factors to do anything constructive. 

Adrenal tumors seem to be more prevalent in larger dogs than small; and there is an increased occurrence in female dogs over male. But other than that, whether or not a dog develops an adrenal tumor is largely a matter of fate. 

Adrenalectomy Questions and Advice from Veterinary Professionals

Miniature Schnauzer
9 Years
Serious condition
0 found helpful
Serious condition

A week ago dog stopped eating and seemed sad
Diagnosed with pancritititus, kidney disease and found a mass on adrenal gland
Been in vets 4 days. Kidneys normal now and they think pancrititis almost ok. Is there any other way ti show if mass is cancer or not and if so if spread than a pay for a ct scan and surgery which risky under a general anesthetic

Callum Turner
Dr. Callum Turner, DVM
1809 Recommendations
If Charlie is otherwise healthy, he should tolerate a general anaesthetic reasonably well at nine years old; unfortunately it is difficult to say what the mass is without the resolution of CT or MRI and even then until it is removed and biopsied we cannot know for 100%. I would recommend removing the affected adrenal gland and a CT will help show any metastasis. Regards Dr Callum Turner DVM

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Lab/Pit mix
5 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms

Drinking lots of water

My dog Margarita was diagnosed with a large tumor of the left adrenal gland. I live in Alameda, CA and some local specialists were willing to do the surgery right away. but I also talked to UC Davis and they recommended to do 2 weeks of treatment and then do the surgery. What should I do? And is the surgery the best option?

Callum Turner
Dr. Callum Turner, DVM
1809 Recommendations

Generally if a benign tumour is suspected, medical treatment is tried first but for malignant tumours surgery is the treatment of choice; however, some Veterinarian like to try medical therapy for a period of time to help stabilise a patient prior to surgery. If Margarita has Cushing’s Disease (or is displaying the symptoms), a benign tumour may be present; but this is something to discuss with your Specialist. I do not like to make decisions without examining a patient and I think you should speak with your Specialist about the options. Regards Dr Callum Turner DVM

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