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- The dog has an allergy to the drug or is hypersensitive to it
- There is the possibility of interaction with another medication the dog is currently taking
- If the fetus is sitting in an abnormal position or is too big to fit through the birth canal
- If the cervix is NOT dilated
- If the dog has uncorrected low blood sugar or calcium levels
- If the oxytocin is not administered properly, it could lead to complications such as a ruptured uterus or excessive pain from uterine cramping
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