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Terramycin is a prescription tetracycline antibiotic that treats various bacterial infections. This broad-spectrum antibiotic is effective against many common types of bacteria including stomach bugs like E. coliand E. histolytica, bacteria that cause conjunctivitis, and the germ responsible for spotted fever.
Tetracyclic antibiotics like Terramycin hinder bacteria’s ability to synthesize proteins and reproduce, preventing them from spreading to other healthy cells and tissues. Additionally, oxytetracycline (Terramycin’s active ingredient) disrupts the cell barrier, causing the intracellular structures inside the bacteria to escape.
Terramycin is available in 4 forms: oral liquids, capsules, injectable liquid, and eye salve. Keep in mind dosage guidelines vary depending on the animal’s history, pre-existing conditions, and the prescribing condition.
Capsules and liquid suspensions: 10 mg/lb by mouth
Intravenous injection: 5 mg/lb
Ophthalmic ointment: 3.5 mg to 5 mg, 2 to 4 times daily
Give oral forms of Terramycin for dogs either an hour before feeding or two hours after feeding. When administering Terramycin ophthalmic ointment, use your finger to gently open the lower eyelid and smear a small amount onto the inside of the lid. Be careful not to scratch your pet’s eye when applying this medication.
A study from the 1950s found that Terramycin virtually eradicated the spread of E. histolytica in an outbreak of confined individuals.
A separate study of canines with a tick-transmitted bacterial infection called ehrlichiosis found the active ingredient in Terramycin to be comparable to doxycycline, with a 100% success rate for the study group.
Terramycin ophthalmic ointment was an effective and long-lasting antibiotic ointment in a more recent study of 10 Beagles. Findings from this study detail that concentrations of oxytetracycline left in the dog’s tear duct 12 hours post-treatment were still much higher than the threshold dosage needed to kill bacterial pathogens.
Typically, Terramycin doesn’t cause adverse side effects besides nausea and vomiting, though some dogs are more sensitive to antimicrobial drugs. Drug manufactures note that this medication can sometimes cause:
Change in tooth color
Change in appetite
Liver and kidney damage
Terramycin can cause flare-ups in canines with colitis and enteritis because it eliminates colonies of beneficial bacteria as well as bad bacteria. Some vets recommend giving dogs prone to digestive problems a probiotic supplement while on antibiotics.
Dogs with liver disease or low liver function should have regular check-ups and blood tests when on this medication. In humans, tetracycline antibiotics can elevate enzyme and bilirubin levels, and cause steatosis of the liver.
Be aware that there are medicines that interact with Terramycin for dogs. Let your vet know if your dog takes any of these medicines and supplements:
Medications or supplements containing Strontium ranelate
Antibiotics are a common cause of drug reaction in canines and humans. Mild reactions usually manifest as one or more of the following symptoms:
Gnawing at the paws
A more serious reaction, called anaphylaxis, can sometimes occur too. Symptoms that distinguish anaphylaxis from other allergic responses are:
Swelling of the face, tongue, or throat
Loss of consciousness
Abnormal heart rate
Rapid onset of symptoms
Yes. Give this medicine according to the vet’s orders until there is no more left in the bottle.
Calcium, iron, and zinc can all interfere with the absorption of Terramycin. The chemicals in Terramycin cling to these molecules which inhibit the body from metabolizing the medicine fully. Avoid giving your dog foods high in these minerals 2 hours before or after this medication.
Even though low concentrations pass into the milk, antibiotics are generally safe for breastfeeding mammals and their offspring. Terramycin is often given as a treatment for mastitis, or milk duct infection.
Antibiotics target the structures in bacteria responsible for protein synthesis since viruses don’t contain these structures; antibiotics are completely ineffective against them.
Bacteria can enter a canine’s body in numerous ways. Dogs can pick up bacteria from eating spoiled food or feces, swimming in bacteria-laden water, or from walking on a dirty surface with a cut on their paw.
You can absolutely contract a bacterial infection from your dog. Make sure you’re using proper hygiene techniques when picking up after your dog and sanitize your hands before and after cleaning your pet’s wounds.
No, only antifungals are effective against fungal pathogens.
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Written by Mel Lee-Smith
Veterinary reviewed by:
Published: 10/06/2020, edited: 10/06/2020
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