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- Weakness of the lower motor neurons, which also include the connective nerves to the muscles and spinal cord; it may subsequently cause partial paralysis of the four legs, if not examined in a timely manner
- Stiffness in the legs, which is an initial occurrence
- Some canines will find it difficult to urinate or pass the feces because of not being able to stoop to carry out this action
- Nervous system continues to progressively deteriorate
- Reduction in reflexes
- Lack of or reduced muscle tone
- Chronic reduction in muscle mass once there is no nerve stimulation
- More severe nerve damage in rear legs
- Labored breathing with dogs severely impacted
- Aphonia or losing the voice
- Motor dysfunction
- Dysphonia or alteration of the voice
- Facial muscles tend to be weak
- Pain or sensitivity to pain
- Toxoplasma gondii infection
- Vaccine reaction
- Autoimmune reaction
- Tick paralysis
- Botulism
- Hypertrophic neuropathy
- Tetanus
- Snake bite
- Lead toxicity
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