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- Spontaneous bleeding
- Excessive bleeding
- Nosebleeds
- Excessive bruising
- Lameness
Hypofibrinogenemia is a deficiency in fibrinogen and is most highly associated with the Saint Bernard and Vizsla breeds and severe bleeding.
Deficiency of Factor VII occurs when there is not enough of a clotting protein called Factor VII, is found in the Beagle, English Bulldog, Alaskan Malamute, Miniature Schnauzer and Boxer breeds, and is associated with bruising and excessive bleeding during surgery.
Hemophilia A is a deficiency of Factor VIII, and the most common congenital bleeding disorder. Females are typically carriers of the disorder while males exhibit symptoms. Dogs with severe cases of Hemophilia A exhibit internal bleeding while others may exhibit excessive bleeding from the umbilical site after birth and excessive bleeding during surgery.
Acquired Clotting Protein Disorders occur as a result of liver disease, as the liver produces most of your dog’s clotting proteins, or in cases of liver toxicity, such as Vitamin K poisoning via rodenticide.
Platelet Disorders are any irregularity in platelet count or functioning, and may be congenital or acquired.
Thrombocytopenia is the condition of having too few platelets, disabling the body’s ability to form clots. Congenital thrombocytopenia can occur when a mother produces antibodies against proteins in the fetus’ platelets that her body deems foreign. Acquired thrombocytopenia is an autoimmune disorder in which a dog’s body destroys its own platelets. It may be caused by a reaction to certain drugs (such as estrogen, aspirin, acetaminophen, and antibiotics) or vaccinations.
Canine Thombopathia is a congenital defect in the function of platelets. There may be the correct number of platelets; however, hey are unable to clot properly. This disease has been found in the Basset Hound breed only and is characterized by symptoms of nosebleed, bleeding gums, and tiny spot-like bruises over the dog’s skin.
Von Willebrand’s Disease occurs in a dog that has a deficiency in von Willebrand’s factor, the protein that regulates the onset of clot formation. This is the most common congenital bleeding disorder and is found in all breeds. However, it is most common in the Doberman Pinscher, German Shepherd, Golden Retriever, Miniature Schnauzer, Pembroke Welsh Corgi, Standard Manchester Terrier, Standard Poodle, Scottish Terrier, Basset Hound and Shetland Sheepdog breeds.
Blood Vessel Disorders may be congenital or acquired as a result of other diseases.
Ehlers-Danlos Syndrome is known as rubber puppy disease or cutaneous asthenia. It is a congenital defect in the proteins that make up the skin’s connective tissue, leading to blood clots and over-sensitive bruising.
Rocky Mountain Spotted Fever is the common name for the disease caused by the Rickettsia rickettsii parasite transmitted by ticks. The parasite kills blood cells, causing vessels to swell. Symptoms include nosebleeds, bruises, bloody urine or feces, and bleeding of the retina.
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