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- Lack of appetite
- Weight loss
- Difficulty breathing/labored breathing
- Weakness
- Lethargy
- An increased heart rate
- An increased respiratory rate
- Cough
- Inability to exercise
- Alveolar emphysema - In alveolar emphysema, the alveoli (small air sacs that are deep in your dog’s lungs) become permanently enlarged and alveolar septal walls are destroyed with no visible build-up of excess tissue
- Interstitial emphysema - In interstitial emphysema air is present in the lung’s connective tissue
- A wound, either internally or in the skin of the dog that allows air into the tissues from the movement of surrounding muscles
- Trauma to the lungs, trachea, esophagus or chest wall that cause ulcerations or lacerations
- Inflammatory lung disease (chronic obstructive pulmonary disease or chronic bronchitis) where a lesion leads to air being able to enter the alveoli but not be released
- Cancer
- Lung parasites
- Congenital bronchial hypoplasia (airways underdeveloped at birth); this is noted in the Pekingese breed of dog
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