Eosinophilic Granuloma Complex Average Cost

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What is Eosinophilic Granuloma Complex?

Eosinophilic granuloma complex commonly occurs in cats and horses, not dogs; however, it has happened. Symptom onset may occur slowly or quickly, may seem mild to severe, and typically appears as some type of skin related reaction. If you see a rash on your dog’s skin or a growth appears that wasn’t there before, go see your veterinarian. Any illness related to symptoms dealing with the skin can lead to secondary infections quickly it not treated. Dogs recover well from eosinophilic granuloma complex with antibiotics and additional steroids if needed.

Eosinophilic granuloma complex in dogs is rare but possible. The symptoms can range from mild to more severe and can manifest in a variety of ways. If your dog develops any type of skin irritation or growth, go see your veterinarian as soon as possible.

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Symptoms of Eosinophilic Granuloma Complex in Dogs

Symptoms can vary in each case of a dog diagnosed with eosinophilic granuloma complex and may include:

  • Rapid onset
  • Nasal and muzzle swelling
  • Pain
  • Exudation
  • Large, swollen erythematous lesions on the muzzle, head, pinna, and periocular area
  • Bumps and nodules on the body


Eosinophilic granuloma complex is actually a term used to describe different diseases that all cause skin inflammation and irritation. It affects each pet differently but in the majority of cases, the same symptoms were found.

Canine eosinophilic granuloma causes yellow raised nodules to develop on the skin. The degree of pruritus varies in each case so presence or absence of this symptom is not indicative to the cause. 

Canine eosinophilic furunculosis is the second disease that is covered by this term. This disease leads to symptoms similar to that of a bug sting reaction. The muzzle will swell, it onsets rapidly, and lesions may appear.

Causes of Eosinophilic Granuloma Complex in Dogs

The cause of eosinophilic granuloma complex in dogs is when he has an abnormal reaction to an insect bite or condition that causes a hypersensitive reaction. It can closely resemble other illnesses but the cause is from the dog’s immune system itself overreacting. It can be considered an auto-immune disease in which the immune system responds to a non-threat like it is one.

Diagnosis of Eosinophilic Granuloma Complex in Dogs

When diagnosing eosinophilic granuloma complex in dogs, the veterinarian will take an impression of the lesion onto a slide so she can view it under the microscope. If your dog does have eosinophilic granuloma complex, the impression will reveal eosinophils. The lesions are similar to other diseases in the animal world, so further diagnostics may need to be run to check for the differential factor of if the lesion is infiltrating other regions.

She will also want to perform general blood work as part of her diagnostic workup. A chemistry panel and complete blood count will be performed to give the veterinarian a general look at your dog’s blood values. Certain white blood cells will be elevated indicating a cause of his symptoms. This will also allow her to check for other underlying issues that could be affecting his health.

Treatment of Eosinophilic Granuloma Complex in Dogs

Most dogs respond well to antibiotics alone. However, many dogs also require an additional corticosteroid to help lessen their symptoms. If symptoms reoccur, you simply administer more medication and the issue should resolve. However, do not self-diagnose your dog. There are other things that could be causing these symptoms and it needs to be addressed properly.

Other medications and therapies may be administered according to your dog’s needs. The veterinarian may want to keep him temporarily for observation, or she may want to see him again in a few days for a recheck.

Recovery of Eosinophilic Granuloma Complex in Dogs

Most dogs recover fully with antibiotics and steroids if needed. However, this can become a chronic condition and can stay dormant in your dog’s system. Symptoms can periodically reappear, especially in times of stress when your dog’s immune system is at its weakest. However, you will simply need to treat it like you did before and it should resolve. 

As soon as you notice some sort of issue with your dog’s skin, take him in to see his veterinarian. While it might seem like a small irritant on his skin, it can quickly develop into something more severe. Also, there is always a chance of a secondary infection developing or other medical condition. While you cannot prevent it from occurring in your dog, you can do your best to respond to it and treat it appropriately.

Eosinophilic Granuloma Complex Questions and Advice from Veterinary Professionals

Manchester Terrier
13 Years
Moderate condition
0 found helpful
Moderate condition

Has Symptoms

nodules on tail.

I have a Manchester terrier who is 13 with this. It's been an issue for the past several months. We have had a biopsy and it's Eosinophilic dermatitis...we finished 4 weeks of antibiotics. It is now mostly concentrated on her tail but is bad. The collar is on her 95% of the day and if I forget for 10 min she goes after her tail making this super difficult. She is now on allergy meds but not seeing an improvement. I'm at a loss.

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Golden Retriever
1 Year
Critical condition
0 found helpful
Critical condition

Has Symptoms

Cough, weight loss, loss of apetite

Hi my dog died last week during exploratory surgery on her lung. They sent the lung off and got the results back today saying it was this condition. However, everything that I am reading is saying that it is a skin condition and her skin was fine. Her lung had tumors in it. I am just confused. Could someone be mistaken?

Dr. Michele King, DVM
Dr. Michele King, DVM
1611 Recommendations
This is typically a skin condition, and uncommon in dogs. Penny may have had an immune condition that caused the tumors in her lungs, however, and histologically they may have appeared similar to that disease. I'm sorry for your loss, that is very sad no matter the reason. If you need to know the cause, you can call your veterinarian and ask them to follow up with the pathologist, as they may not have had enough information to work with. Again, I am very sorry about Penny.

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