Pancreatic Cancer (Insulinoma) in Dogs
Written By Grace Park
Published: 03/03/2016Updated: 08/25/2021
Pancreatic Cancer (Insulinoma) in Dogs - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost
What is Pancreatic Cancer (Insulinoma)?
Insulinoma is a cancerous growth (also known as a tumor) located on the pancreas in dogs. A healthy pancreas helps produce insulin, which controls the glucose levels in the dog’s body. Insulinomas prevent the pancreas from functioning properly. These tumors cause the insulin levels to rise dramatically, which in turn, cause the glucose levels to decrease. Low levels of glucose can lead to dogs collapsing, or suffering from seizures or other neurological problems.
Insulinoma are tumors on the dog’s pancreas, the organ which regulates and controls both insulin and glucose. These tumors prevent the pancreas from functioning normally. The dog’s decreased glucose levels begin to cause weakness and neurological disorders, and can lead to death if left untreated.
Youtube Play
Pancreatic Cancer (Insulinoma) Average Cost
From 367 quotes ranging from $3,000 - $10,000
Average Cost
$8,500
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Symptoms of Pancreatic Cancer (Insulinoma) in Dogs
 If your pet begins to show behavioral changes that cause you concern, do not delay in seeking a veterinary opinion. Symptoms of insulinoma include the following:
While physical collapse is the most common symptom, a dog exhibiting any of these symptoms should be given medical attention immediately. Symptoms can be sporadic due to the release of insulin; it may help to record any of these signs as they appear to assist your veterinarian in the diagnosis.
Causes of Pancreatic Cancer (Insulinoma) in Dogs
Insulinoma is caused by cancerous growth on the pancreas. The presence of these tumors cause the dog’s insulin levels to increase, in turn decreasing the glucose in their bloodstream. Without a functioning pancreas, dogs can become weak and suffer neurological problems. It is also likely that this cancer will metastasize and spread throughout the body, possibly causing death.
Diagnosis of Pancreatic Cancer (Insulinoma) in Dogs
Diagnosis of insulinoma often begins after the dog has exhibited several symptoms consistent with the disease. Your veterinarian will likely request that a blood sample be taken to examine the glucose levels. If low glucose levels are found, your veterinarian may want to continue to test for insulinoma and monitoring the dog’s glucose levels. To do so, they will likely order multiple blood samples - particularly ones where the dog is fasting and not fasting to see if there is persistent hypoglycemia. Additional tests for “amended insulin:glucose ratio” (AIGR) may be performed, particularly if the dog’s insulin levels are on the lower end but still considered to be relatively normal. Your veterinarian will also make sure to rule out any other diseases that could be causing the symptoms or changes in glucose levels during this time. In additional to blood tests, diagnostic imaging may also be utilized to determine the presence of a tumor, along with its possible size (though this method can be difficult due to the small size of the pancreas). Unfortunately, the most effective way of diagnosing insulinoma is visualization of the tumor during abdominal surgery, during which the surgeon will examine the organ for any growths. However, if the veterinarian does not feel comfortable putting the dog through surgery (or has other confirmation that the tumors are present), they will likely begin treatment without direct visualization of the tumors.
Insulinoma can be expensive to treat. If you suspect your dog has insulinoma or is at risk, start searching for pet insurance today. Brought to you by Pet Insurer, Wag! Wellness lets pet parents compare insurance plans from leading companies like PetPlan and Trupanion. Find the “pawfect” plan for your pet in just a few clicks!
Treatment of Pancreatic Cancer (Insulinoma) in Dogs
Emergency treatment is needed. If your dog collapses or exhibits any of the other symptoms, contact your veterinarian immediately. Immediate treatment typically involves administering glucose to the dog, though steroids and intravenous fluids may also be needed. Once the tumor is located, removal will depend on several factors, such as the dog’s age and current health status. If the procedure is not considered too risky, your veterinarian may elect to surgically remove the tumor. Additional treatment will be needed if the growths have metastasized and spread throughout the body. Medications, as well as chemotherapy, can help treat insulinoma but there are some serious side effects to these treatments. Your veterinarian will likely also consult with you regarding your pet’s nutrition - a dietary plan may be put in place to help monitor your dog’s glucose levels.
Petted logo

Worried about the cost of treating your pet's symptoms?

Pet Insurance covers the cost of many common pet health conditions. Prepare for the unexpected by getting a quote from top pet insurance providers.

Get a quote

background
Recovery of Pancreatic Cancer (Insulinoma) in Dogs
Prognosis is poor if insulinoma is detected late or symptoms are ignored. Due to the aggressiveness of this cancer, it is often metastatic and malignant. If insulinoma is caught early, survival rates are fair. Treatment options such as surgery, chemotherapy and dietary management may help extend the pet’s life.
Pancreatic Cancer (Insulinoma) Average Cost
From 367 quotes ranging from $3,000 - $10,000
Average Cost
$8,500
arrow-up-icon
Top
Pancreatic Cancer (Insulinoma) Questions and Advice from Veterinary Professionals
dog-breed-icon
American Pit Bull Terrier
dog-name-icon
Bruiser
dog-age-icon
Ten Years
thumbs-up-icon

29 found this helpful

thumbs-up-icon

29 found this helpful

how do you know when it's time to say goodbye to your friend? My was diagnosed 8 months ago. In the past month he has started having seizures at least once a week. We have started giving him doses of sugar (agave or corn syrup) with his meals as well as .25 mg of CBD oil 2 times per day and that seemed to help. He was seizure free for almost 3 weeks until this morning. He had 2 major seizures back to back. We can continue to feed him and dose him like we are because it did seem to help but how long do we do this? Is he in pain when he is having a seizure? We understand the inevitable for our poor friend but don't know when enough is enough....Help.
July 9, 2018
Answered by Dr. Michele K. DVM
29 Recommendations
Bruiser is probably not in pain when he is having seizures, but they are probably hard on him, physically. I think there comes a point when he may just be tired, and it may be time to let him go. It is hard for me to say whether he is there yet without seeing him, but asking your veterinarian their opinion will help, as they are there to be his advocate. I am sorry that that is happening to him.
July 10, 2018
Was this question and answer helpful?
dog-breed-icon
American Bulldog
dog-name-icon
Max
dog-age-icon
7 Years
thumbs-up-icon

31 found this helpful

thumbs-up-icon

31 found this helpful

My pet has the following symptoms:
Weakness
We found out that my dog has cancer in his pancreas and the doctor had said that the optional thing to do is to put him to sleep my family and I were planing to do so on 11/27/17 but we have been so frustrated Because we are trying to see if there is another way to keep him at least for a little of months . Also to let you know the doctor had said that if we try to do chemotherapy there is one out of hundred that it would work . What can I do ? - sincerely Kelly
Nov. 26, 2017

31 Recommendations
This is a difficult decision and there are many variables here including the progress, symptoms presenting among others; whilst a terminal prognosis is given, some cases may be managed in the short term but it is difficult to give you any specifics without examining Max as well as seeing x-ray, ultrasound and blood results. If you have doubts, I would advise visiting another Veterinarian to confirm you’re making the right choice. Regards Dr Callum Turner DVM
Nov. 26, 2017
My little dog has pancreatic cancer, diagnosed in Sept. 2017, it is now 2.6.18, he does not have too much longer, however the Palladia is very effective. The draw back on the Palladia is that it can cause bleeding stomach ulcers. It worked well for a while, had to take him off of it because of the ulcers. The steroids helped keep the blood sugar up, however, they are not as effective after several months, had to start giving him Karo Syrup in a shringe once a day, then twice a day, now 3 times a day. He is now doing an IV therapy Chemo, but not near as good as the Palladia was. I know we don't have too much longer, however, we have made it 4 months now since diagnosis. Unfortunetly it had aleady spread to other areas and they said operating was not an option. Just a note to those trying to do all they can, adding probiotics to the diet helped Jack, I also added other cell enhancing suppliments. Baby food works well when they have ulcers. Bless you on your journey - Corey
Feb. 6, 2018
Corey
Was this question and answer helpful?
dog-breed-icon
Chihuahua
dog-name-icon
Maxine
dog-age-icon
10 Years
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Lethargy
Seizures
Loss Of Balance
Blood In Stool
my baby maxi turned 10 years old 6/9/2019 and it honestly came out of the blue. in the late afternoon she had bloody diarrhea. this was common so i thought she may have ate something she wasn’t supposed to. in the middle of the night she needed to use the restroom (she was sleeping on my bed). when i put her down she couldn’t stand up her body was spasming(a seizure basically). i didn’t know what was going on so i immediately took her to the 24hr emergency vet. her glucose levels were really low and so she stayed overnight while getting blood tests +being monitored on her sugar levels. she did really well eating when we visited her one day but then her sugar levels would never get back up to a healthy amount. i couldn’t afford to keep her there i was already $4000 in debt so there wasn’t much of an option other than to put my angel down on 6/11/19. it was a really low chance of her surviving even with surgery,chemo, strict diet etc but she did her best those couple of days and at least made it to double digits. miss her everyday. if it happens to your baby don’t feel bad it can happen out of nowhere for no reason what’s important is that you do your best to help them while theyre doing their best to fight it.
dog-breed-icon
German Shepherd
dog-name-icon
Cruizer
dog-age-icon
12 Years
thumbs-up-icon

0 found this helpful

thumbs-up-icon

0 found this helpful

My pet has the following symptoms:
Pancreatitis
Back in Oct 2018 Cruizer had 2 episodes of pancreatitis - both treated & cleared up but came back a third time so I requested bloods - insulin levels where high & Cruiz was really unwell this time - in 12 yrs he has never gone off food so I knew it was bad - ultrasound in early November revealed 2 tumours in pancreas only (one 9cm & one 1.4cm) - it wasn’t showing anywhere else via ultrasound & other blood levels were normal so we were told it’s definateky a cancer but cant determine without surgery what type - either adenomacarcinoma or insuloma or both as 2 cancers - but surgery was not an option as even if they could discover what the cancers are chemo etc won’t cure it so we were offered palliative care - today is 13th Jan 2019 & Cruizer is still going strong - no signs of pancreatitis & he is eating & pooing without problem - if I hadn’t seen the ultrasounds pics of the tumours I would not believe he has cancer - he has had to come of Pred as blood test last week showed that the steroids were causing a liver enzyme to be a prob & at risk of Cushing Disease so we have dropped the dosage to half every second day - his diet has always be BARF but we have added more feeds - every 4 hrs nigh & day - Tramadol is at 150mg every 5-6hrs & Metrogyl is for the gut to prevent infection from steroids - he has a few skin issues due to Pred so has Cephalexin for next few weeks whilst Pred is decreased. So what does this say - it says no one can predict time - we would have euthanised him on the day of diagnosis as he was so unwell but our vet wanted to try the regime he is on & he responded to it & is very well at the moment - we see the vet weekly to check lymph’s & do bloods fort nightly to compare but nothing is showing other than the reaction to long term Pred so if he continues along we will redo ultrasound in March to assess tumours & if they have spread - our vet & the specialists involved in his care have no idea why he is not worsening but we are all stoked that he is doing so well & not suffering. Hopefully we can get more time but we just go day by day & be grateful for every e tra one we get with him!
Pancreatic Cancer (Insulinoma) Average Cost
From 367 quotes ranging from $3,000 - $10,000
Average Cost
$8,500
Wag Compare logo

Get a free pet insurance quote in less than 60 seconds!

Easily compare quotes from the most trusted pet insurance companies in the United States.

Get a quote

background
Need pet insurance?
Need pet insurance?

Learn more in the Wag! app

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install


© 2025 Wag Labs, Inc. All rights reserved.


© 2025 Wag Labs, Inc. All rights reserved.

Wag! Premium service

Get Wag! Premium & save on all services

Health & Wellness

Chevron down icon

Become a Caregiver

Chevron down icon

Wag! App

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install

Wag! for Pet Parents

Five starsFive starsFive starsFive starsFive stars

43k+ reviews

Install

pet-parent-illustration

Pet Caregiver

Find pet care jobs on Wag!

Approved Caregiver?

Get the app