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What is Pancreatic Cancer (Insulinoma)?

Insulinoma is a cancerous growth (also known as a tumor) located on the pancreas in dogs. A healthy pancreas helps produce insulin, which controls the glucose levels in the dog’s body. Insulinomas prevent the pancreas from functioning properly. These tumors cause the insulin levels to rise dramatically, which in turn, cause the glucose levels to decrease. Low levels of glucose can lead to dogs collapsing, or suffering from seizures or other neurological problems.

Insulinoma are tumors on the dog’s pancreas, the organ which regulates and controls both insulin and glucose. These tumors prevent the pancreas from functioning normally. The dog’s decreased glucose levels begin to cause weakness and neurological disorders, and can lead to death if left untreated.

Pancreatic Cancer (Insulinoma) Average Cost

From 367 quotes ranging from $3,000 - $10,000

Average Cost

$8,500

Symptoms of Pancreatic Cancer (Insulinoma) in Dogs

 If your pet begins to show behavioral changes that cause you concern, do not delay in seeking a veterinary opinion. Symptoms of insulinoma include the following:

  • Collapse
  • Incoordination
  • Seizures
  • Disorientation
  • Muscle tremors
  • Weakness
  • Lethargy
  • Depression

While physical collapse is the most common symptom, a dog exhibiting any of these symptoms should be given medical attention immediately. Symptoms can be sporadic due to the release of insulin; it may help to record any of these signs as they appear to assist your veterinarian in the diagnosis.

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Causes of Pancreatic Cancer (Insulinoma) in Dogs

Insulinoma is caused by cancerous growth on the pancreas. The presence of these tumors cause the dog’s insulin levels to increase, in turn decreasing the glucose in their bloodstream. Without a functioning pancreas, dogs can become weak and suffer neurological problems. It is also likely that this cancer will metastasize and spread throughout the body, possibly causing death.

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Diagnosis of Pancreatic Cancer (Insulinoma) in Dogs

Diagnosis of insulinoma often begins after the dog has exhibited several symptoms consistent with the disease. Your veterinarian will likely request that a blood sample be taken to examine the glucose levels. If low glucose levels are found, your veterinarian may want to continue to test for insulinoma and monitoring the dog’s glucose levels. To do so, they will likely order multiple blood samples - particularly ones where the dog is fasting and not fasting to see if there is persistent hypoglycemia. Additional tests for “amended insulin:glucose ratio” (AIGR) may be performed, particularly if the dog’s insulin levels are on the lower end but still considered to be relatively normal. Your veterinarian will also make sure to rule out any other diseases that could be causing the symptoms or changes in glucose levels during this time. In additional to blood tests, diagnostic imaging may also be utilized to determine the presence of a tumor, along with its possible size (though this method can be difficult due to the small size of the pancreas). Unfortunately, the most effective way of diagnosing insulinoma is visualization of the tumor during abdominal surgery, during which the surgeon will examine the organ for any growths. However, if the veterinarian does not feel comfortable putting the dog through surgery (or has other confirmation that the tumors are present), they will likely begin treatment without direct visualization of the tumors.

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Treatment of Pancreatic Cancer (Insulinoma) in Dogs

Emergency treatment is needed. If your dog collapses or exhibits any of the other symptoms, contact your veterinarian immediately. Immediate treatment typically involves administering glucose to the dog, though steroids and intravenous fluids may also be needed. Once the tumor is located, removal will depend on several factors, such as the dog’s age and current health status. If the procedure is not considered too risky, your veterinarian may elect to surgically remove the tumor. Additional treatment will be needed if the growths have metastasized and spread throughout the body. Medications, as well as chemotherapy, can help treat insulinoma but there are some serious side effects to these treatments. Your veterinarian will likely also consult with you regarding your pet’s nutrition - a dietary plan may be put in place to help monitor your dog’s glucose levels.

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Recovery of Pancreatic Cancer (Insulinoma) in Dogs

Prognosis is poor if insulinoma is detected late or symptoms are ignored. Due to the aggressiveness of this cancer, it is often metastatic and malignant. If insulinoma is caught early, survival rates are fair. Treatment options such as surgery, chemotherapy and dietary management may help extend the pet’s life.

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Pancreatic Cancer (Insulinoma) Average Cost

From 367 quotes ranging from $3,000 - $10,000

Average Cost

$8,500

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Pancreatic Cancer (Insulinoma) Questions and Advice from Veterinary Professionals

Need pet health advice? Ask a vet

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Ask a Vet

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Bruiser

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American Pit Bull Terrier

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Ten Years

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Serious severity

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1 found helpful

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Serious severity

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how do you know when it's time to say goodbye to your friend? My was diagnosed 8 months ago. In the past month he has started having seizures at least once a week. We have started giving him doses of sugar (agave or corn syrup) with his meals as well as .25 mg of CBD oil 2 times per day and that seemed to help. He was seizure free for almost 3 weeks until this morning. He had 2 major seizures back to back. We can continue to feed him and dose him like we are because it did seem to help but how long do we do this? Is he in pain when he is having a seizure? We understand the inevitable for our poor friend but don't know when enough is enough....Help.

July 9, 2018

Bruiser's Owner

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Dr. Michele K. DVM

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1611 Recommendations

Bruiser is probably not in pain when he is having seizures, but they are probably hard on him, physically. I think there comes a point when he may just be tired, and it may be time to let him go. It is hard for me to say whether he is there yet without seeing him, but asking your veterinarian their opinion will help, as they are there to be his advocate. I am sorry that that is happening to him.

July 10, 2018

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Max

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American Bulldog

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7 Years

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Serious severity

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3 found helpful

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Serious severity

Has Symptoms

Weakness

We found out that my dog has cancer in his pancreas and the doctor had said that the optional thing to do is to put him to sleep my family and I were planing to do so on 11/27/17 but we have been so frustrated Because we are trying to see if there is another way to keep him at least for a little of months . Also to let you know the doctor had said that if we try to do chemotherapy there is one out of hundred that it would work . What can I do ? - sincerely Kelly

Nov. 26, 2017

Max's Owner


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3320 Recommendations

This is a difficult decision and there are many variables here including the progress, symptoms presenting among others; whilst a terminal prognosis is given, some cases may be managed in the short term but it is difficult to give you any specifics without examining Max as well as seeing x-ray, ultrasound and blood results. If you have doubts, I would advise visiting another Veterinarian to confirm you’re making the right choice. Regards Dr Callum Turner DVM

Nov. 26, 2017

My little dog has pancreatic cancer, diagnosed in Sept. 2017, it is now 2.6.18, he does not have too much longer, however the Palladia is very effective. The draw back on the Palladia is that it can cause bleeding stomach ulcers. It worked well for a while, had to take him off of it because of the ulcers. The steroids helped keep the blood sugar up, however, they are not as effective after several months, had to start giving him Karo Syrup in a shringe once a day, then twice a day, now 3 times a day. He is now doing an IV therapy Chemo, but not near as good as the Palladia was. I know we don't have too much longer, however, we have made it 4 months now since diagnosis. Unfortunetly it had aleady spread to other areas and they said operating was not an option. Just a note to those trying to do all they can, adding probiotics to the diet helped Jack, I also added other cell enhancing suppliments. Baby food works well when they have ulcers. Bless you on your journey - Corey

Feb. 6, 2018

Corey

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Maxine

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Chihuahua

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10 Years

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Critical severity

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0 found helpful

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Critical severity

Has Symptoms

Lethargy
Seizures
Loss Of Balance
Blood In Stool

my baby maxi turned 10 years old 6/9/2019 and it honestly came out of the blue. in the late afternoon she had bloody diarrhea. this was common so i thought she may have ate something she wasn’t supposed to. in the middle of the night she needed to use the restroom (she was sleeping on my bed). when i put her down she couldn’t stand up her body was spasming(a seizure basically). i didn’t know what was going on so i immediately took her to the 24hr emergency vet. her glucose levels were really low and so she stayed overnight while getting blood tests +being monitored on her sugar levels. she did really well eating when we visited her one day but then her sugar levels would never get back up to a healthy amount. i couldn’t afford to keep her there i was already $4000 in debt so there wasn’t much of an option other than to put my angel down on 6/11/19. it was a really low chance of her surviving even with surgery,chemo, strict diet etc but she did her best those couple of days and at least made it to double digits. miss her everyday. if it happens to your baby don’t feel bad it can happen out of nowhere for no reason what’s important is that you do your best to help them while theyre doing their best to fight it.

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Cruizer

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German Shepherd

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12 Years

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Mild severity

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Mild severity

Has Symptoms

Pancreatitis

Back in Oct 2018 Cruizer had 2 episodes of pancreatitis - both treated & cleared up but came back a third time so I requested bloods - insulin levels where high & Cruiz was really unwell this time - in 12 yrs he has never gone off food so I knew it was bad - ultrasound in early November revealed 2 tumours in pancreas only (one 9cm & one 1.4cm) - it wasn’t showing anywhere else via ultrasound & other blood levels were normal so we were told it’s definateky a cancer but cant determine without surgery what type - either adenomacarcinoma or insuloma or both as 2 cancers - but surgery was not an option as even if they could discover what the cancers are chemo etc won’t cure it so we were offered palliative care - today is 13th Jan 2019 & Cruizer is still going strong - no signs of pancreatitis & he is eating & pooing without problem - if I hadn’t seen the ultrasounds pics of the tumours I would not believe he has cancer - he has had to come of Pred as blood test last week showed that the steroids were causing a liver enzyme to be a prob & at risk of Cushing Disease so we have dropped the dosage to half every second day - his diet has always be BARF but we have added more feeds - every 4 hrs nigh & day - Tramadol is at 150mg every 5-6hrs & Metrogyl is for the gut to prevent infection from steroids - he has a few skin issues due to Pred so has Cephalexin for next few weeks whilst Pred is decreased. So what does this say - it says no one can predict time - we would have euthanised him on the day of diagnosis as he was so unwell but our vet wanted to try the regime he is on & he responded to it & is very well at the moment - we see the vet weekly to check lymph’s & do bloods fort nightly to compare but nothing is showing other than the reaction to long term Pred so if he continues along we will redo ultrasound in March to assess tumours & if they have spread - our vet & the specialists involved in his care have no idea why he is not worsening but we are all stoked that he is doing so well & not suffering. Hopefully we can get more time but we just go day by day & be grateful for every e tra one we get with him!

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Marley

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German Shepherd Labrador Retriever

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8 Years

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Serious severity

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3 found helpful

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Serious severity

Has Symptoms

My baby, Marley, a shepard lab mix died in sept of 2004 or so. He was diagnosed 2 years before that. We took him to the vet when we noticed disoriented behavior. We were told that his tumors were like little blisters all over his pancreas and were inoperable or would not likely extend his life. I was told that he would die within 6 months. I was told to feed him several small meals to keep blood sugar steady and to give him small bits complex carbs if I noticed any signs of disorientation. I gave him cubes of bagels or chunks of meat or the like on the regular, about every hour to keep him ok. Worked very well. He stayed active with my other dog. I kept him in the yard worried he would have an issue away from home and he was too big for me to carry any distance. His last six months he did start having seizures and i used a squeeze bootle of honey, and would carefully squeeze a little honey just a bit at a time between his cheek and gum so he would not choke and he would quite quickly come out of it. Always move them carefully away from things they can hurt themselves on. Always be extremely careful around the mouth during seizures as they snap their mouths closed quite loudly and I assume its quite a strong bite! Anyway I did get up at night to give him his snacks and make sure he drank and went outside. He had a really happy 2 years with us and his dog buddy. Our other lab mix oliver. When it was time, you know. It happened rapidly. Hee couldnt " be a dog " anymore. He couldnt stand up, much less get around with oliver. He looked tired Slept alot. Lost interest in food. And then seemed restless yet could not get up. I fashioned a towel to support his weight to help him get out to do his business, and spend time outside. Bless him he smiled and was so happy after getting out to the yard to lay in the sun his, last full day. I then had trouble keeping his blood sugar up and he was very agitated and disoriented the next morning. I think he was quite confused. I had arranged with my vet to come to my home when it was time. He came mid morning, my other animals were able to say goodbye, and understand what happened, Marley was in his home surrounded by love and comfort. And we said goodbye. Taking care of him for 2 years nigjt and day was a lot of work.but i had the honor of walking by my best friend on his final journey till the end. I miss and love him so much.

Pancreatic Cancer (Insulinoma) Average Cost

From 367 quotes ranging from $3,000 - $10,000

Average Cost

$8,500

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