
- Uncontrolled trembling or twitching
- Sensitivity to touch
- Repetitive pawing or scratching
- Pain and vocalizations that might be related to pain
- Nervous system disorder
- Kidney failure
- Certain medications
- Toxicity or poisoning
- Injury or trauma
- Strong emotional responses like excitement, fear, or anxiety
- Deep or REM sleep stages
- Itchiness from dry skin, mites, or fleas
- Low blood calcium
- Hypoglycemia or low blood sugar
- Vitamin or mineral deficiencies
- Electrolyte imbalances
- Rabies
- Seizure disorders like epilepsy
- Feline hyperesthesia or rolling skin disease
- Congenital or genetic conditions
- Pain
- Weakness
- Certain cancers, especially those affecting the nervous system or muscles
- How often the twitching occurs
- Whether it happens only while sleeping or also when awake
- Which parts of the body are affected
Since muscle trembling can be episodic, it may not always happen during the vet visit. If possible, record a video of the twitching episodes at home. This can help your vet assess the severity and pattern of the movements.
- Bloodwork: A complete blood cell count (CBC), biochemistry panel, and electrolyte test can help detect infections, inflammation, or imbalances that might contribute to cats twitching while sleeping or while awake.
- Urinalysis: Testing a urine sample can reveal issues with kidney function, dehydration, or metabolic disorders.
- Imaging (X-rays, Ultrasound, or MRI): If twitching or trembling is linked to nerve damage, muscle disorders, or underlying injuries, imaging scans may be needed to get a clearer picture.
Worried about the cost of treating your pet's symptoms?
Pet Insurance covers the cost of many common pet health conditions. Prepare for the unexpected by getting a quote from top pet insurance providers.

- Provide a warm, quiet sleeping area
- Provide a balanced diet to prevent metabolic issues
- Reduce stress with routine playtime and environmental enrichment
- Use flea prevention to avoid external irritants
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