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What is Mycoplasma Infection?

Mycoplasma infection is caused by a type of bacteria that acts as a parasite in the blood, causing anemia and other signs of infection. Antibiotic treatment may be needed to overcome the disease, especially in cats with poor immune performance.

Mycoplasma infection is a medical condition that affects cats, dogs, farm animals, and people. The bacteria are present in most environments. Most healthy animals will experience little to no symptoms, but the very young or old or those with immune disorders may have severe anemia and other signs of infection. Mycoplasma commonly causes respiratory symptoms like bronchitis and pneumonia, but can cause infection in other parts of the body as well.

Mycoplasma Infection Average Cost

From 355 quotes ranging from $150 - $350

Average Cost

$220

Symptoms of Mycoplasma Infection in Cats

The symptoms of mycoplasma infection can vary based on several factors. The most common symptom is anemia. Clinical signs can vary depending on the severity of the infection and the immune status of the cat. Symptoms are considerably more severe in animals who have immune disorders and weakened immune systems. The location of the infection also affects the type of symptoms the cat will have. Infections can be located in the respiratory system, urinary tract, joints, or reproductive system. 

Common symptoms include:

  •  Anemia
  • Lethargy
  • Lack of appetite
  • Weakness
  • Fever
  • Yellowing of skin (Icterus or Jaundice)
  • Pale skin and mucous membranes
  • Nasal or ocular (eye) discharge

Symptoms related to the infection location include:

  • Sneezing
  • Trouble breathing
  • Coughing
  • Pneumonia
  • Joint inflammation
  • Difficulty moving
  • Urinary tract infection
  • Abscesses
  • Reproductive problems (including miscarriage and poor fetal development)
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Causes of Mycoplasma Infection in Cats

Mycoplasma infection is caused by exposure to the bacteria. This can occur in almost any setting, as this type of bacteria is very common. It can spread easily between animals, making it common in shelters and kennels as well as multi-pet homes. The infection is not limited to cats, and can be caught from or given to other companion animals. Humans are also at risk of infection. Immunodeficiency and conditions that weaken or suppress the immune system increase the risk of contracting the disease.

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Diagnosis of Mycoplasma Infection in Cats

A veterinarian can diagnose Mycoplasma infection using various medical testing procedures to visually confirm the organisms in blood, urine, or other fluids. Before proceeding to this step, a physical examination and medical history of the cat are required. Be prepared to discuss the symptoms and timeframes associated with your pet’s illness. If clinical signs point to a bacterial infection, your veterinarian will collect fluids for testing purposes. The fluid collected will depend on the type and location of the symptoms your cat is exhibiting. For example, a urinalysis or urine testing are effective in situations where the animal is experience related symptoms. Joint fluid, mucus, and blood samples can also be analyzed. Dye staining has been shown to be an effective method for locating the bacteria that cause the infection in cats.

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Treatment of Mycoplasma Infection in Cats

No single treatment or protocol is considered consistently effective in treating Mycoplasma infection. Treatments will vary depending on the severity of symptoms and location of the infection within the body. Antibiotics are the most common form of treatment, but the type of antimicrobial the bacteria is susceptible to is not the same in all cases. To completely overcome the disease, treatments may continue for an extended period of time. Although treatment plans may differ, most cats will not require hospitalization unless their symptoms are very severe or in animals with poor immune function. Recommended treatments may include:

Antibiotics:

 Most cats will require a minimumseven to ten-day course of antibiotics to treat the primary infection. Because Mycoplasma infections can be hard to eradicate, more than one course of antibiotics may be necessary for a full recovery. 

Analgesics:

 If pain, inflammation, or fever is severe, this category of painkiller may be prescribed. Be sure to carefully follow your veterinarian’s instructions if you will be dosing your pet with painkillers at home. Too much of this type of medication can be very dangerous to your cat. 

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Recovery of Mycoplasma Infection in Cats

Most cats with normal immune function are expected to make a full recovery from the disease, although it may take several weeks to completely rid your pet of the infection. Once antibiotic treatment has begun, symptom improvement can be expected within a few days. Anemia symptoms may take longer to recover from. Carefully monitor your pet’s food and water intake while they are recovering to make sure your cat is receiving the proper nutrition to recover.

Reinfection is a risk with Mycoplasma, so pet areas should be thoroughly cleaned and disinfected. Continued disinfection should be maintained until your pet has completed their antibiotic treatments. If there are multiple animals in the home, isolation may be necessary to prevent the spread of infection. Take your pet back to the veterinarian if symptoms get worse, don’t improve after a week’s time, or come back.

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Mycoplasma Infection Average Cost

From 355 quotes ranging from $150 - $350

Average Cost

$220

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Mycoplasma Infection Questions and Advice from Veterinary Professionals

Need pet health advice? Ask a vet

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Ask a Vet

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Coca

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Domestic cat

dog-age-icon

8 Years

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Moderate severity

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0 found helpful

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Moderate severity

Has Symptoms

Weight Loss

Hi, i have a cat who has been diagnosed with mycoplasma. She is taking treatment and the 5 other cats in the household have been tested but turned out to be negative. Due to the incubation period should the 5 other cats be retested after 30 days?

Aug. 3, 2018

Coca's Owner

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Dr. Michele K. DVM

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1611 Recommendations

Mycoplasma is a very common organism in the environment, and it typically does take an underlying problem to have it cause disease. If the other cats seem healthy and are doing well, you may be fine to monitor them for any clinical signs since they have tested negative. Since I do not know the full history or situation for Coca, however, it would be best to check with your veterinarian, as there may be complications that I'm not aware of.

Aug. 3, 2018

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Sherry

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Maine Coon

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3 Years

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Moderate severity

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0 found helpful

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Moderate severity

Has Symptoms

Mouth Lump
Stomatitis With Infection

I have a Maine Coon female 3 years old, carrying eosinophilic granuloma. Recently she contracted Mycoplasma felis and she is now treated with Clindamicina 0.7 ml for day and cortison. Then we try a teeth extraction surgery for decrease any possible inflammation trigger. I have other 2 cats, a young male and a female 2 years old. They should be breeding cats so I performed a respiratory tract microbiological test on eye and nose mucous fluids that resulted positive for M felis for both. The 2 cats have no symptoms. What to do? Thanks for attention. Patrizia Iansa Read more at: https://wagwalking.com/cat/condition/mycoplasma-infection

July 26, 2018

Sherry's Owner

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recommendation-ribbon

3320 Recommendations

Mycoplasma infections with M. felis may be seen in asymptomatic cats and the decision whether to treat these cases would be down to your Veterinarian; however if you are breeding cats it may be worth treating regardless but you should discuss this with your Veterinarian. Regards Dr Callum Turner DVM

July 27, 2018

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Adi

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short hair

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2 Months

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Fair severity

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0 found helpful

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Fair severity

Has Symptoms

Fleas

I had a 1 year old cat who I had to unfortunately put down due to mycoplasma. We have have ended up with a new kitten who needed a home but we haven’t managed to flea bomb our house yet. Is there a high chance of our new kitten being bitten by the fleas that infected our last cat. We are bombing our house in a few days but I’m very concerned for the next few days as I’ve seen a flea on the new kitten even though he has flea treatment.

July 6, 2018

Adi's Owner

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3320 Recommendations

Mycoplasma infections are transmitted by fleas and it is possible for the new kitten to be bitten and infected; the use of an effective topical spot on flea & tick control medication is required like Revolution (selamectin). You should continue to monitor Adi and visit your Veterinarian if you have any concerns. Regards Dr Callum Turner DVM

July 6, 2018

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Callie

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domestic short hair

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1 Year

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Serious severity

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2 found helpful

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Serious severity

Has Symptoms

Pain

My one-year-old cat was diagnosed with micoplasma and treated for three weeks with antibiotic + prednisone. Seemed to get better. Now she is having back pain and has trouble walking, jumping, etc. Acts like an old cat. x-rays show no structural problems in the back, and doc is suggesting the micoplasma may be causing joint pain as her body works to build red blood cells in the bone marrow . Is that common? I've read that in humans micoplasma pneumoniae can cause arthritis. Does that happen in cats, and if so, is it temporary. She is starting another 3 weeks course of antibiotics and steroids.

June 18, 2018

Callie's Owner

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recommendation-ribbon

3320 Recommendations

Polyarthritis from Mycoplasma may occur in cats but is rare; however treatment with doxycycline or enrofloxacin are commonly used, but both have their pros and cons which your Veterinarian would discuss with you. Regards Dr Callum Turner DVM https://veterinary-practice.com/article/treatment-of-mycoplasma-spp-infections-in-cats

June 19, 2018

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Fuzzy

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Persian

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4 Months

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Serious severity

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0 found helpful

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Serious severity

Has Symptoms

Weakness And Loss Of Appetite.

My 3.5 month old Persian kitten is showing signs of Mycoplasma according to my vet. He is yet to receive his final booster vaccine (3in1 and rabies already given). His RBC count is 11 and Haemoglobin is 4.3. with hospitalization and antibiotics he is yet to improve,it has been over 24 hrs. Should he get steroids. What are his chances?

June 6, 2018

Fuzzy's Owner

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Dr. Michele K. DVM

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1611 Recommendations

Without more information about Fuzzy, I can't really comment on his treatment plan or his prognosis, unfortunately - there is a lot more to know than those two lab values. Since he is currently being treated, it would be very reasonable to ask your veterinarian more details about his condition, his plan, and his prognosis. I hope that he is okay.

June 6, 2018

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Sabrina

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Domestic shorthair

dog-age-icon

11 Months

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Moderate severity

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0 found helpful

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Moderate severity

Has Symptoms

High Rbc, Hct

My rescue kitten was diagnosed in March with mycoplasma. Originally her symptoms had been high proteins and white blood cells and mild anemia. She had been treated with amoxicillin and then 6 weeks of clindamycin. In March blood work dramatically changed with normal proteins but high rbc. She was treated with 6 weeks of doxycycline. RBC continued to rise and now she has been diagnosed with polycythemia. I'm trying to understand how this fits together and what to do for her. Clinical, she appears healthy.

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Miya

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Tuxedo short hair

dog-age-icon

6 Months

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Fair severity

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1 found helpful

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Fair severity

Has Symptoms

Sneezing
Sneezing Breathing Difficulties

I adopted a feral cat at two months old. she was fine for the first couple weeks and then started developing system symptoms of an upper respiratory infection. I took her to my first vet and he prescribed two rounds of two different types of anabiotic’s which temporarily did something but then she just got significantly worse and I finally took her to a different vet and after lots of test we figured out that she had mycoplasma and she’s been on doxycycline liquid form for a month and her demeanor is extremely happy and she’s running around but her throat And nose are still clogged up. I am very concerned that the doxycycline is causing esophageal stricture’s in her throat and her nose is still swollen like rhinitis. I am concerned because I feel like she needs more anabiotic’s but I’m worried about her throat and I spent $2500 already and I am wondering what else I can do. I’m sure the vet is going to prescribe her to be on doxycycline for longer due to the fact that she didn’t get treated with correct medicine sooner but I’m so worried about her throat. The next step might be to go see a specialist maybe she has a polyp in her nose. I just am running out of money Over here but really concerned that her nose and throat aren’t going to develop well because of Mycoplasma and side effects of the medicine. 🙃

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Kaze

dog-breed-icon

Sphynx

dog-age-icon

1 Year

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Moderate severity

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1 found helpful

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Moderate severity

Has Symptoms

Sneezing
Coughing
Congestion
Runny Nose
Ear Infections
Wheezing
Mouth Breathing
Asthma

My boy started showing signs of a respiratory problem at around 9 weeks old. He was misdiagnosed for about a month until they tested him for bacterial strains, which showed positive for mycoplasma. He was given the normal medicines that are used to view him, but he ended up developing bronchitis. The upper respiratory congestion continued to worsen no matter what antibiotic he was taking. His nasal congestion caused ear infections and ate start of stomatitis. It’s been over a year since and we have done CT scans, biopsies, xrays, ultrasounds, etc. to find the best course of action to no success. Adding “PlaqueOff” supplements to his food has helped his teeth and breath, although he is still constantly sneezing wads of thick mucus as well as wheezing. Doxycycline seems to only work for the first week or two Of his rounds before the symptoms come back. I’m so worried that he will get pneumonia so I’m trying anything that can help him.

dog-name-icon

Boogie

dog-breed-icon

Maine Coon

dog-age-icon

15 Years

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Serious severity

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2 found helpful

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Serious severity

Has Symptoms

Passed Over The Rainbow Bridge

A 10 year battle with M Felis in my precious Maine Coon. At 5 years, my MC "suddenly started sneezing, became hoarse, then stopped eating. A culture determined it was M Felis, other diseases were ruled out. Boogie was declining fast, so a feeding tube was inserted. He was given azithromycin and thankfully survived. He continued to have reoccurrent episodes, 3 to 4 a year for the next 10 years of his life and the zith lost effectiveness. His last year, he developed pneumonia, surviving the first episode with Baytril injections but he lost the battle upon the 2nd pneumonia infection. He was my precious baby, and we fought this disease as hard as we could. I am sharing so that others will know that you can provide a quality and long life to your pet but there may life long battles.

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Chunks

dog-breed-icon

domestic medium hair

dog-age-icon

3 Months

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Moderate severity

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1 found helpful

pill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filledpill-rating-filled

Moderate severity

Has Symptoms

Weight Loss
Anemia
Lethargy
Pica

My kitten has been sick and fighting some mystery illness. A month ago he got tested for fiv/felv and showed up positive for FeLV. However I was told it was probably a false positive. He was put on metronidazole to help his chronic diarrhea, but when it stopped he still wasn't gaining weight. I took him to another vet and his RBC was low so they suggested it could be mycoplasma. He was on doxycycline for 2 weeks and when I took him back he was still sick. His blood count was lower than before, he had a fever of 103 and the vet noticed a fed mark on his eye and said it was protein. Now he's on clavamox and panacur to see if he'll improve. I'm wondering if I should get a second opinion because the vet now thinks he might have FiP (which scares me)?

Mycoplasma Infection Average Cost

From 355 quotes ranging from $150 - $350

Average Cost

$220

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