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Cosequin for dogs is a nutritional supplement aimed at helping dogs keep moving by supporting joint health. Cosequin is veterinarian-recommended and made with quality ingredients, including glucosamine hydrochloride and sodium chondroitin sulfate. Some products, such as the extra strength supplement, will include extra ingredients like methylsulfonylmethane. Maximum strength soft chews also have omega-3s such as EPA and DHA.

This supplement comes in several formulations. Speak with your veterinarian to decide which one is best for your dog. For information on dosage, efficacy, side effects, and considerations for Cosequin, continue reading.


There are a few formulations under the Cosequin label. Discuss the best dosage for your dog with your veterinarian. The dosage for Cosequin capsules is listed below.

Each capsule contains 500mg of glucosamine hydrochloride, 400 mg of sodium chondroitin sulfate, and 5mg of manganese. 

Dosage Instructions

Start by using an “initial” dose for the first 4 to 6 weeks. Afterward, a maintenance dose is recommended to maintain the results.


Glucosamine is a mild anti-inflammatory and helps with the production of cartilage. It also helps to prevent further breakdown of cartilage. Chondroitin promotes the retention of water, helping to maintain elasticity in the cartilage. It also slows the destruction of cartilage. Methylsulfonylmethane is a natural anti-inflammatory and pain reliever.

Early results may be apparent in a few days; however, the full effects of how this will help your dog may not be seen for 4 to 6 weeks. If you do not think the desired effect is being reached, you can discuss your expectations with the veterinarian. An adjustment to the supplement dosage may be made. Once the desired effect is reached, Cosequin for dogs can be reduced to the maintenance dosage.

Side Effects of Cosequin

Cosequin for dogs is a short-acting supplement. Its effects should dissipate within 24 hours of stopping the supplement. Side effects are rare with Cosequin; if your dog experiences any, they may be:

  •  Loose stool (at most, diarrhea)
  • Gas

In some formulations (Minis and DS Plus MSM, for example), methylsulfonylmethane is an added ingredient. There may be side effects that occur.

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  • Itching
  • Fatigue
  • Insomnia
  • Headaches
  • Allergy symptoms, if present, may worsen


Talk to your veterinarian before putting your dog on any type of supplement or natural therapy. Together, you will decide if Cosequin for dogs is suitable.

Drug interactions

Cosequin should be considered carefully in dogs on the following medications:

  • Antidiabetics
  • Doxorubicin
  • Etoposide
  • Heparin
  • Warfarin

Allergic reactions and sensitivity

Although rare, there is a chance of allergy or adverse reaction. Caution is also taken in dogs who have diabetes mellitus. Consistent blood sugar monitoring is essential. Additionally, dogs who are on low potassium diets should be given Cosequin for dogs with caution since some formulations contain potassium. Dogs with asthma should be closely monitored if put on Cosequin.

The use of Cosequin on pregnant or breastfeeding animals has not been studied. 

Frequently asked questions

How do I know if my dog has joint pain?

If your dog has joint pain, they may appear lame and often stiff upon rising. Your dog may lick the affected joint, which could be swollen. They may refuse to stand and you could see behavioral changes like moodiness or reluctance to play.

How do I know if my dog has osteoarthritis?

A dog with osteoarthritis may limp, appear sore when touched, vocalize pain, show aggression, lose their appetite, and more.

How do I store Cosequin?

Most often, supplements are stored at room temperature, away from sunlight. Check the instructions on the box to be on the safe side.

What if I miss giving my dog their dose of Cosequin?

If it is near the time for the next dose, skip the dose. Do not double up on doses of Cosequin.

Do I need a prescription for Cosequin?

There are several places where you can purchase the supplement. However, talk to your veterinarian first to ensure that Cosequin is suitable for your dog.

*Wag! may collect a share of sales or other compensation from the links on this page. Items are sold by the retailer, not Wag!.

Written by a Pugs lover Grace Park

Veterinary reviewed by:

Published: 12/29/2020, edited: 12/29/2020

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