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 .Dasuquin by Nutramax is a line of dietary supplements that promote joint health in canines and felines. Dasuquin contains glucosamine and chondroitin, which are thought to improve mobility, slow cartilage destruction, and prevent the breakdown of the fluid that lubricates the joints.  


The cost of Dasuquin varies depending on the dosage strength, formulation, and quantity. Chewable tablets and soft chews are available with or without MSM and are dosed for small to medium and large dogs. Tablets are available in 84 to 150 count bottles for $40 to $100, while soft chews range from $50 to $80.


.Dasuquin soft chews come in 2 strengths. The small and medium dog formula contains 600 mg of glucosamine, 250 mg of chondroitin, and 45 mg of avocado/soybean unsaponifiables (ASU) powder. The large dog formula contains 900 mg of glucosamine, 350 mg of chondroitin, and 90 mg of ASU powder. 

Dasuquin soft chews with methylsulfonylmethane (MSM) have the same dosage and ingredients, except they contain methylsulfonylmethane for additional cartilage support. The formula for smaller dogs contains an added 400 mg of MSM, whereas the large dog formula has 800 mg. 

Dosage for Dasuquin soft chews (with and without MSM):
  • 10 to 29 lbs — 1 small to medium soft chew daily for 4 to 6 weeks; then 1 every other day
  • 30 to 59 lbs — 2 small to medium soft chews daily for 4 to 6 weeks; then 1 daily thereafter 
  • 60 to 129 lbs — 2 large-dog soft chews for 4 to 6 weeks; then 1 daily thereafter

.Dasuquin tablets are available with or without MSM and contain the same active ingredient dosages as the soft chews. Dogs under 10 lbs should only take Dasuquin tablets since they can be split in half, whereas the soft chews cannot. The chewable tablets come in small and large dog formulations, though the dosages are slightly different.
Dosage for Dasuquin chewable tablets (with and without MSM):

  • Up to 10 lbs — half a small dog tablet daily for 4 to 6 weeks; half a tablet daily thereafter
  • 10 to 29 lbs — 1 small dog tablet daily for 4- 6 weeks; half a tablet daily thereafter

  • 35 to 50 lbs — 2 small dog tablets daily for 4-6 weeks; 1 tablet daily thereafter
  • 60 to 120 lbs — 1 large dog tablet daily for 4-6 weeks; 1 tablet daily thereafter

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*The Dasuquin website states that you can alter your dog's maintenance dosage to fit your dog's needs, especially on days when they're more active or showing symptoms. 

Dosage instructions

Since Dasuquin products have a chicken flavor, most dogs take it voluntarily. Give this medication in the mornings like you would a treat. If your dog doesn't like the flavor of the soft chews, you can hide them in a piece of meat or cheese. You can crush the chewable tables into a fine powder and mix it with wet food or dry kibble and broth.


Though studies haven't been done on this product specifically, there's a lot of data to support the clinical significance of glucosamine, chondroitin, and avocado/soybean extract for joint health. 

In one controlled study, glucosamine and chondroitin increased the range of motion in dogs' jaws with poor functionality of the temporomandibular joint. 

 .Research shows that avocado and soybean unsaponifiables prevent the breakdown of muscle and cartilage in mammals. Additional evidence supports that ASU can rebuild damaged cartilage due to its anabolic properties. Several studies indicate that ASU supplements can also help with pain management for osteoarthritis and decrease the need for pain medication.  

 .Studies of mice and rabbits with osteoarthritis show that methylsulfonylmethane reduces inflammation by inhibiting the production of proteins that trigger an immune response. 

Active ingredients in Dasuquin

The active ingredients in Dasuquin products are glucosamine hydrochloride, sodium chondroitin sulfate, and avocado/soybean unsaponifiable powder. 

Side effects

 .Glucosamine and chondroitin supplements can occasionally cause mild side effects in canines, including:

  • Increase in water consumption
  • Excitability
  • Trouble sleeping
  • Allergic reaction
  • Frequent urination
  • Gastrointestinal upset
  • Stomach bloating
  • Edema
  • Scratching
  • Swelling of the eyelids


Glucosamine and chondroitin are usually safe in normal doses; however, studies show that abnormally high doses over a long time can cause organ failure in dogs and humans. 

In recent years research has emerged tying glucosamine and chondroitin to glaucoma in elderly humans, though it's unclear if these supplements pose a risk to canine eye health. 

Unfortunately, animal supplements aren't regulated like human supplements and can contain harmful ingredients like lead. Poor quality control can also lead to discretions between the ingredient list and what's actually in the bottle. Ask your vet to recommend a good-quality joint health supplement for your dog. 

Drug interactions

NSAIDs may increase gastrointestinal upset in canines who take this supplement. Try spacing out the doses if your dog needs pain relief but doesn't tolerate these medicines together. Glucosamine may increase the effects of blood thinners like warfarin. Ask your vet before giving this medicine to dogs on anticoagulants

Allergic reactions and sensitivity

Glucosamine and chondroitin supplements may cause an allergic response in dogs sensitive to fish since it's often extracted from shark cartilage. Canines with a sulfur allergy should not take Dasuquin with MSM.

Frequently asked questions

Is Dasiquin a multivitamin for dogs?

Although Dasquin products contain a proprietary blend of vitamins, it's not a complete multivitamin. Dasquin Advanced does, however, contain additional vitamins that the regular and MSM formulas do not. 

Can my pet take Dasuquin for dogs t if their food already contains Glucosamine and Chondroitin?

Yes, this is completely safe to mix with joint support foods. 

Can I give Dasuquin for dogs to my cat?

Although small doses probably won't hurt your cat, Dasiquin makes products that cater to the specific needs of felines and are already the right dosage.

*Wag! may collect a share of sales or other compensation from the links on this page. Items are sold by the retailer, not Wag!.

Written by a Pugs lover Grace Park

Veterinary reviewed by:

Published: 12/28/2020, edited: 12/28/2020

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