Carprofen Poisoning Average Cost

From 34 quotes ranging from $300 - 2,500

Average Cost

$500

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What is Carprofen Poisoning?

Carprofen is a medication commonly prescribed to canines with osteoarthritis; it works well for pain management and is very palatable making it a medicine well suited for canine ailments. The positive results seen by pet owners who give this medicine to their dogs regularly is well documented. The anti-inflammatory properties of this drug are also known to be beneficial. Many canines are prescribed carprofen long-term, though patients on this medication must be followed by the veterinarian to monitor the effects of the drug. Carprofen has caused toxicity in dogs who have been on the medication long-term; however, cases of poisoning are most commonly seen with an accidental overdose of the medication. Our canine companions enjoy the flavor of this medication and will help themselves to it if available. Symptoms will vary depending on the amount consumed and can range from vomiting to abdominal pain, and gastrointestinal perforation in very severe cases.

Carprofen is a nonsteroidal anti-inflammatory drug used in the veterinary field for pain management. Prescribed as a medication to alleviate inflammation and pain associated with arthritis, as well as pain management after surgery, ingestion of more than the prescribed amount can result in serious consequences.

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Symptoms of Carprofen Poisoning in Dogs

The severity of signs of carprofen poisoning will be contingent on how much of the medication was ingested by your pet. The peak plasma concentration (the highest level of medication in the blood) is reached in one to three hours.  Symptoms you may see in your dog will vary.

  • Vomiting (can be bloody)
  • Diarrhea (can be bloody)
  • Abdominal pain
  • Weakness
  • Lethargy
  • Muscle twitching

In severe cases, additional signs will be seen.

  • Tremors
  • Seizures
  • Gastrointestinal perforation
  • Stupor
  • Coma

Signs of kidney failure are as follows.

  • * Blood in the urine
  • Extreme thirst
  • Excessive urination
  • Fatigue
  • Vomiting

In addition, if the liver is experiencing damage, jaundice will be present in the form of yellow colored skin, mucus membranes, and whites of the eyes.

Types

Carprofen poisoning in dogs can be acute after the ingestion of a large qunatity over and above the prescribed amount. Chronic carprofen poisoning may result if your dog develops a sensitivity to it over a period of time. There are side effects and possible adverse reactions to carprofen in some canines, this is why a dog who is on a regular prescription will be monitored through regular check-ups with the veterinarian.

Causes of Carprofen Poisoning in Dogs

Although adverse reactions to the drug are rare, ingestion of high amounts due to a canine gaining access to his medicinal supply is common. NSAID’s in general can be responsible for gastrointestinal issues with long-term use; therefore, an overdose of a chewable tablet or capsule will cause your pet to experience stomach upset in mild cases, to gastrointestinal irritation or perforation in severe cases of poisoning. Reduction of gastric acid secretion and blood flow to the mucosa can occur causing hemorrhaging along with kidney and liver failure. Other risk factors for severe carprofen poisoning can be:

  • Dogs with coagulation disorders such as von Willebrand’s disease
  • Other medication that is prescribed concurrently like glucocorticoids and sulfonamides
  • Dehydration
  • Predisposition to liver and kidney disease
  • Compromised liver and kidney due to age

Diagnosis of Carprofen Poisoning in Dogs

If you have witnessed your pet indulging in his carprofen tablets, do not question or wait for the result. A visit to the veterinary clinic is essential. Bring the empty packaging with you, along with any other medications your pet may be on (if any). The veterinarian will base his diagnostic decisions on clinical signs exhibited by your dog (like nausea and abdominal pain) and will also rely on information you can provide. The veterinarian may ask questions as he examines your pet’s mucus membranes and eyes and takes his vital signs.

  • How long has your pet been on the carprofen?
  • What is the reason is it was prescribed?
  • How long ago did you realize that he may have ingested an overdose amount?
  • What have the symptoms been so far?
  • Are they getting worse as time progresses or staying at the same intensity?
  • How much is he drinking and urinating?

The veterinary team will take blood tests in the form of a complete blood count and blood serum chemistry to evaluate levels such as BUN (blood urea nitrogen), creatinine, electrolytes, and liver enzymes. A urinalysis will determine the concentration or dilution of the urine.

Treatment of Carprofen Poisoning in Dogs

Decontamination

Depending on the timing between ingestion and hospitalization, the veterinary team may choose to induce vomiting and administer active charcoal (to bind the remaining medication).

Supportive Care

IV fluids will provide much supportive and corrective care. Nausea medication, antibiotics, gastroprotectants, vitamin K1 for the liver, and diazepam if there are seizures can all be administered during supportive therapy. Kidney and liver function, as well as urine outflow, will be assisted through intravenous fluids. Your furry family member will be monitored carefully and will remain in the hospital as needed until blood levels are normal and organ function has returned.

Recovery of Carprofen Poisoning in Dogs

Studies show that cases of carprofen poisoning in dogs can have a good prognosis with timely medical intervention. If there has been severe kidney or liver damage or if the ulceration and hemorrhaging in the gastrointestinal tract and stomach are extremely damaging, the chances of recovery become guarded. If your pet is able to return home after treatment, he may require special care and will need a follow-up appointment with the veterinarian to re-evaluate with blood tests. As with all other types of medication, carprofen should be kept out of reach of children and pets.

Carprofen Poisoning Questions and Advice from Veterinary Professionals

Riley
Lab mix
4 Years
Mild condition
0 found helpful
Mild condition

Has Symptoms

vomited puddles of brown water

Medication Used

Sucralfate

My 49 lb Basset mix tore the ankle pad on behind her right front ankle. We did not discover this until yesterday, after it was already inflamed and infected. She was prescribed 50mg of Rimadyl as well as antibiotics. She was given 50mg of Rimadyl (half a pill) at 6pm. I made her comfortable and left to go a a TCU football game. I returned at 11pm to discover my 50 lb Lab/Collie mix had chewed the cap off and eated the entire bottle of 13 and 1/2 100mg pills of Rimadyl. We rushed him to the Emergency Vet where they immediately induced vomiting and administered fluids and charcoal. I was not able to pay $2000 to have him watched in the hospital, so they pumped fluids under his skin (he looked really lumpy!) and allowed me to bring him home, with instructions to only give ice chips overnight. Then I am to give him 1gm tablet of Sucralfate in the morning, wait 2 hours, then give him small, frequent meals of dry dog food or plain chicken breast. Overnight, he threw up about 5-6 times, puddles of a dark-brown liquid. While appearing sad, so far this morning he had enough energy to follow a scent trail in the back yard and bark at a passing jogger, and trotted back to the house with his tail high. So far this morning, he has kept down the Sucralfate, drank a little bit of water, and eaten 10 pieces of kibble.
Should I take him back to the vet for additional fluids today?

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Jazzi
Black Lab
7 Years
Mild condition
1 found helpful
Mild condition

Has Symptoms

Head Trembling

OK so I think I may have scewed up on the dosage of Recovery EQ extra strength for horses. My vet recommended this for my black lab's arthitis, and I've been giving it to her for 3 years now, since she was 4 years old. The directions say 1/4 scoop which is just over 1/2 TBSP twice daily for each 300 pounds, which translates to .14 of a TBSP twice daily for my 80 pound lab. When we started this medication, my vet's assistant calculated the dosage for me, and I now think it may have been incorrect, as it came to just under 1 TBSP twice daily, which is about 7 times more than the recommended dosage, I think! No wonder each 1 kg container has only been lasting 5 or 6 months as opposed to the one year my vet had said it should last. My lab started getting head tremors shortly after we started this in 2015, but not knowing about side effects, and not knowing I was over-dosing my dog, both me and my vet didn't connect the dots. My vet simply asked me to keep a record of dates and frequencies of the tremors, warning that it may or may not be the beginnings of epilepsy. Of course there may be many instances of tremnors when my lab was unattended in her yard, but the ones I witnessed were as follows. 2015 - 12 occasions from April to November, one for 5 min, one for 7 min, several for 1, 2 or 3 min, and a couple for 1/2 min. 2016 - 6 occasions from May to Sept, ranging from 1/2 min to 2 min. 2017 - only 2 occasions, 2 1/2 min in May and 1 min in Nov. 2018 - 4 occasions, 1 min in Jan, 2 min in Feb, and 2 times for 1 min each in March. Nothing since then. So it looks like it has become less over time, and my vet says that is a good thing and not to worry about epilepsy...yet! My concern is that I now wonder if my lab is tremoring as a result of EQ overdosing over time. I will start reducing the dosage right away, and see if that helps as well. Do you have any opinions or knowledge about all this?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
The equine version and the small animal version of this product are formulated differently and whilst they contain the same ingredients they are not in the same proportions; I would recommend moving to Recovery SA Extra Strength as this is formulated for small animals and the dosage requires no conversion. I’ve also popped a link at the bottom so that you may contact the manufacturer on their toll free number if you have any product specific questions. Regards Dr Callum Turner DVM http://recoveryeq.com/usa#ingredients http://recoverysa.com/us https://purica.com/contact-us/

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Hp
Beagle Harrier
11 Years
Mild condition
1 found helpful
Mild condition

Has Symptoms

Lethargy

Hello! I am reaching out for help. The vet prescribed my 38 lb 11 year old beagle 1/2 a 75mg tablet every 12 hrs. He ate a whole one for his first dose. What should i do?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Carprofen (Rimadyl) may be administered as 1mg/lb twice per day or 2mg/lb once per day; I would not expect to see any adverse effects from taking the whole day dose at once compared with dividing it every twelve hours. Continue tomorrow with the divided dose as per your Veterinarian’s instructions. Regards Dr Callum Turner DVM

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Ziggy
Chow/german shepherd
2 Years
Mild condition
1 found helpful
Mild condition

Has Symptoms

Vomiting

Our 96 pound chow/shepherd got into a bottle of rimadyl that was prescribed for our other 13 year old shepherd/husky for her end stage breast cancer. There were 6 100 mg tablets in the bottle and I seen it right away so I rushed him to the vet and he was given 2 doses of peroxide to endure vomiting, he didnt vomit. So they gave him some activated charcoal and a shot so he would not vomit the charcoal up and sent us home. It's been 1 week now and he has not acted any differently but the past 2 days, he has been vomiting...2 times yesterday and once today already. Should we be worried he has liver or kidney damage?

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
I would be worried about kidney damage, or GI damage, yes. It would be a great idea at this point to get a blood panel checked with your veterinarian to see what his blood values are, and see if he needs IV fluid therapy at this point.

I talked to our vet and she said to keep an eye on him and keep giving him omeprazole for another 4 days,in case of gi issues. I am supposed to watch for blood in his stool and blood if he vomits. If he starts getting lethargic, not wanting to eat or drink or any other abnormal behaviors.

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Freckles
Australian Shepherd
13 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms

Seizures

I have a 13 yr old full blooded Australian Shepherd. the vet gave us carprofen to give to her twice a day 50 mg each. After 3 doses she had a bad seizure we didn't realize it was the medicine and continued to give it to her for another 2 1/2 days. She had 8 50mg pills in all.It has now been 3 1/2 days since her last dose and she is still having at least 5 seizures a day basically anytime she gets up to walk she has a seizure and losses her bladder. She doesn't drink and she was drinking up to 4 bowls of water a day. She just lays around and doesn't move at all. Is there any hope she will recover from this?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
At therapeutic doses the side effects and adverse reactions to carprofen (Rimadyl) are minimal and usually comprise gastrointestinal symptoms associated with long term use; seizures are a rare reaction to carprofen and should improve. If you haven’t already, you should consult with your Veterinarian regarding supportive and symptomatic care during this time as well as alternative medications. Regards Dr Callum Turner DVM

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Rosco
French Bulldog
12 Weeks
Serious condition
0 found helpful
Serious condition

Has Symptoms

none

My dog is getting this pill for 3 days every 12 hours . It's 25mg and he only gets 1/2 of one every 12 hours . But my husband accidentally gave it to him 2 hours early will he be okay ? What should we do ? He only ways 10 pounds

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
Thank you for your email. A 2 hour difference should not cause any ill effects for him. Monitor for signs of GI upset, including vomiting, diarrhea, or a decreased appetite, and have him seen if any of those are occurring, but it is likely that he will be fine. I hope everything goes well for Rosco!

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Oscar
Chihuahua
8 Years
Critical condition
0 found helpful
Critical condition

Has Symptoms

Seizures

Last year, I gave my dog Rimadyl that was prescribed to another dog. I had good intentions of helping him with pain, but I now blame myself for his death. He was 12 lbs., and I gave him a total of 50mg in four small pieces within 24 hours. A little over 24 hours after I had given him the last small piece, he began having seizures. I took him to the ER and told them what I had done. He had also recently been on Prednisone before I gave him the Rimadyl and was given 2 injections the day after I had given it to him. He was being treated for a slow gate. The ER vet reprimanded me for giving him the medicine. She called the poison control and they said it didn't sound like a toxic issue, but something neurological. They kept my dog for about 10 hours and administered medicines. He continued to have the seizures and I ended up having to euthanize him. I cannot forgive myself for what happened. My vet told me that I did not cause his death, but I still believe I did. He had written possible brain lesion in his file while he was being treated prior to his death, but I still believe I caused my dog's death. I beat myself up over and over for what I did. Did I cause the death of my dog? How can I forgive myself?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Firstly, I know that you gave Oscar Rimadyl (carprofen) with the best intentions, but there is a reason why there are prescription medicines, over the counter medicines and why Veterinarians have crippling student loan debt; many times unintentional poisoning, overdose or adverse reaction by an owner giving a medication prescribed to one dog to other. From your description I do not believe you contributed directly to Oscar’s death as you gave (4mg/lb) two times the recommended dose (2mg/lb); whilst animal safety studies have shown that dogs can tolerate doses higher than you gave over a long period of time, below is an excerpt from the prescribing information: “In separate safety studies lasting 13 and 52 weeks, respectively, dogs were administered orally up to 11.4 mg/lb/day (5.7 times the recommended total daily dose of 2 mg/lb) of carprofen. In both studies, the drug was well tolerated clinically by all of the animals. No gross or histologic changes were seen in any of the treated animals. In both studies, dogs receiving the highest doses had average increases in serum L-alanine aminotransferase (ALT) of approximately 20 IU. In the 52-week study, minor dermatologic changes occurred in dogs in each of the treatment groups but not in the control dogs. The changes were described as slight redness or rash and were diagnosed as non-specific dermatitis. The possibility exists that these mild lesions were treatment related, but no dose relationship was observed.” www.rimadyl.com/content/DisplayPDF.pdf?docName=RIM016007.pdf It is possible that Oscar has a preexisting condition which presented itself around the same time as the Rimadyl administration, I cannot say for certain what the cause was; I would have recommended a necropsy to determine the cause of death to help understand this situation. Regards Dr Callum Turner DVM

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Izzy
Black Lab
2 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms

none

One of my 4 dogs got into a bottle of carprofen while we were not home. I am not really sure which dog it was. All of the dogs are relativley large, the smallest being 50-60 lbs. The bottle had about forty-two 100mg tablets in it. They had to of gotten into the bottle 2-3 hours ago. I have not noticed any symptoms since I found the empty bottle. Do you think they will be okay?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Carprofen (Rimadyl) is toxic in dogs in large amounts over 40mg/kg, given the number of tablets possibly consumed between one or all of the dogs you should visit an Emergency Veterinarian immediately for an examination and fluid therapy to prevent kidney damage as well as getting medication to support the liver and other supportive and symptomatic care. Regards Dr Callum Turner DVM www.petpoisonhelpline.com/poison/carprofen/ http://veterinarymedicine.dvm360.com/toxicology-brief-managing-acute-carprofen-toxicosis-dogs-and-cats www.rimadyl.com/pdf/rimadyl_injectable_pi.pdf

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Annie
Beagle
1 Year
Serious condition
0 found helpful
Serious condition

My one year old beagle mix climbed on the counter and got my other dog's medicine. It was in a child proof container, but Annie chewed through the bottle. It was 10 Vetprofen 75 mg tablets. I called the emergency vet and they said to call poison control. I called them and paid $60 for them to tell me to go to the emergency vet. The emergency vet said it would cost a minimum of $250. I simply don't have it. What can I do? Make her throw up, give her activated charcoal?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
If Annie consumed ten 75mg tablets we know that 750mg was ingested, with a female Beagle weighing around 9kg (20lbs) we can say that a total acute dose of 83.3mg/kg was consumed; we know from literature that kidney and liver damage may occur at ingestions over 40mg/kg and supportive/symptomatic care (notably fluids, silybin and SAMe) should be given. We are already past inducing vomiting and activated charcoal which should have been done within an hour or two; now it is all about supportive care. Regards Dr Callum Turner DVM www.vetoquinolusa.com/sites/uscountry/files/vetprofen-caplets-insert.pdf http://veterinarymedicine.dvm360.com/toxicology-brief-managing-acute-carprofen-toxicosis-dogs-and-cats?id=&sk=&date=&pageID=2 www.petpoisonhelpline.com/poison/carprofen/

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Titus
Akita
11 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms

Diarrhea

On 7/6 we took our dog to the vet for skin issues and also because his arthritis and mobility was not improving with his once a day 100mg rimadyl. He was diagnosed with a bad case of dermatitis and a secondary bacterial infection of the skin. He was given a Cytopoint injection to stop his itching and redness and started on Simplicef. It was also decided that for his size he could be taking 200mg of Rimadyl per day. The vet determined that he had arthritis in all of his joints but also in the lumbosacral area. He was also started on Hills j/d prescription diet (gradual). He is a 100 lb Akita, 11 1/2 years old. On 7/11 he started having diarrhea. I called the vet and was instructed to stop everything and start a bland diet. His diarrhea was like dark brown water that just shot straight out. He could hold it but it was straight liquid. After two days on bland diet with no improvement I called the vet again and was prescribed Tylan powder. My dog, who still had a healthy appetite at this point, did not like the Tylan powder, but we got him to take it with his meal. He didn’t eat dinner and the next morning he vomited all of his meal. On 7/16 I called the vet to report no improvement and now vomiting meals. 7/17 we went in to see the vet. Blood test was run, examined abdomen, and did ultrasound. All tests normal, no swelling. No jaundice. She prescribed metronidazole and to continue bland diet. His appetite has somewhat returned. But the same watery diarrhea continues. It is more of an orangey Brown. He is keeping his food down. But without any pain med his mobility is not great. vet suspects the increase in rimadyl but I’m wondering also about the cytopoint injection and the antibiotics?? This has been a disaster. Though his skin is much improved.

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
I"m sorry that is happening, but glad that Titus's skin has improved. Diarrhea is one side effect of Rimadyl, even though that dosage is safe for him, and a less common side effect of Cytopoint. The only thing that may help that I'm not sure if you are doing would be to add some probiotics to his food to help with his intestinal health. Once you have the diarrhea back under control, you can start him back on the Rimadyl and see how he tolerates it, or there are other pain medications that he might be able to take, such as Galliprant and Gabapentin - you can discuss those medications with your veterinarian.

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Jake
Jack Russell
15 Years
Fair condition
2 found helpful
Fair condition

Has Symptoms

none

My 20 lb, 15 yr old Jack Russel mix got into his bottle of Rimadyl while I was at work. I don’t know how many were in the bottle but at most there were 7 75-mg tablets. He could have done this anytime in the last 12 hours (my guess is earlier vs later in the day). He’s not showing any symptoms and is eating, drinking, and pottying normally. Are we out of the woods?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Symptoms of carprofen (Rimadyl) poisoning include vomiting, diarrhea, bloody vomit, black-tarry stool, loss of appetite, lethargy, increased urination or thirst, abdominal pain as well as seizures or death in severe cases; I would take Jake into see your Veterinarian to be on the safe side as some serious symptoms may take time to present so it would be useful to have a once over to be cautious along with some fluid therapy if required. Regards Dr Callum Turner DVM

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Leo
Boston Terrier
5 Years
Serious condition
0 found helpful
Serious condition

Has Symptoms

Pain

My dog was prescribed Rimadyl for pain from removal of a split nail. He had the prescribed dose for 2.5 days. By the evening of the 2nd day he seemed like he was in a lot of pain, not associated with the toenail. He would yelp in pain and was quite hunched over when walking; refused to jump up or down from the couch. I took him to the vet on the 3rd day and they indicated it could be an adverse effect from the medication so instructed to stop the meds. The 4th day he was in what appeared to be excruciating pain as he yelped almost any time he moved. His appetite was non-existent. By day 5 he appeared to be better he ate and pooped; but then the evening of day 6 he appeared to be in a lot of pain again, yelping with movement and very lethargic. Day 7 and 8 he appeared better again but now on the morning of day 9 he is in extreme pain again, yelping and whining. (the dog is a 5 year old Boston Terrier with no health conditions)

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Rimadyl (carprofen) is a commonly used non-steroidal anti inflammatory drug which is normally well tolerated in dogs, however with any medication there are mild side effects and adverse reactions which affect a small number of animals; gastrointestinal symptoms are most commonly seen in dogs with vomiting and diarrhoea presenting most often, however other reactions including loss of appetite, gastrointestinal ulceration, blood in the stool, pancreatitis and these may cause severe abdominal pain as well. In these cases, supportive and symptomatic care is the only real course of action; try to encourage appetite with abland diet (boiled chicken and rice in regular small portions) and monitor for improvement. Regards Dr Callum Turner DVM www.rimadyl.com/pdf/rimadyl_injectable_pi.pdf

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GRYFF
Jack Russell Terrier
18 Months
Fair condition
0 found helpful
Fair condition

Has Symptoms

Sleepy

My 18 pound Jack Russell was prescribed caprofen 75mg, to be given 1/4 of a pill twice a day as needed. I accidentally gave him his first dosage as a full pill in one sitting. He hasn't shown any symptoms other than being a bit sleepy. I realized my mistake 5 hours after giving him the medicine. Should I take him to the vet?

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
a 4X dosage of Carprofen may not cause problems if given once, but may cause GI ulceration or kidney damage. To be careful, it would be a good idea to have him on IV fluid therapy and stomach protectants for 48 hours, and have his kidney values checked to make sure that he is okay. I hope that all goes well for Gryff.

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Harley
Labrador Retriever
5 Years
Critical condition
1 found helpful
Critical condition

Has Symptoms

Lethargy

Medication Used

Carprofen

My lab is only 5 years old and was prescribed Carprofen for his back pain a month ago. Today, he is fighting for lis life and is told only has weeks to live because of kidney failure. Could the Carprofen be the cause of this. He is still in critical care and has been for 5 days. His creatine live went from 10- 9- 9.6 in those 5 days. I am so at a lost at how this could happen. The carprofen is the only think I can think of.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
At a normal dosage in a perfectly otherwise healthy dog (apart from the back pain) it is unlikely that carprofen (Rimadyl) would cause kidney failure although it is possible, just unlikely; toxicity can be expected when doses over five times the normal dose are given. Regards Dr Callum Turner DVM

I am currently enduring the same ordeal with my Corgi. Except this happened much quicker. He went into the vet for hip pain and was prescribed Rimadyl. Two weeks later he is dying of liver and kidney failure. Did Harley make it out of this? If so, how?

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Kenz
Puggle
8 Years
Mild condition
0 found helpful
Mild condition

Has Symptoms

none

I accidentally gave my dog an extra dose of Rimadyl. She gets 1/2 every 12 hours, they are 75mg. She had one at 8:00am, 5:30pm, and 10:30pm. She is a 30-34lb puggle. Will she be ok?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Rimadyl (carprofen) is tested at one, three and five times the recommended dose, when administered at five times the recommended dose there are no significant adverse reactions. Keep an eye on Kenz and continue the course of treatment the next day as usual, if you notice any symptoms on this page visit your Veterinarian. Regards Dr Callum Turner DVM “In target animal safety studies, Rimadyl was administered orally to healthy Beagle dogs at 1, 3, and 5 mg/lb twice daily (1, 3 and 5 times the recommended total daily dose) for 42 consecutive days with no significant adverse reactions” www.rimadyl.com/pdf/rimadyl_injectable_pi.pdf

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Jabez & Asher
Lab Pei
2 Years
Moderate condition
1 found helpful
Moderate condition

My labs ate at 6:30 this morning. At 7 I found one with a rimadyl bottle chewed up and empty. There were aprox 6-7 100mg chews. My labs are about 100 lbs. I’m not sure which ate them or if they shared. Would it be a toxic amount if one ate them all?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Rimadyl (carprofen) has been tested in dogs at up to 10mg/lb twice per day which is more than Jabez or Asher would have consumed if they eat them alone (around 7mg/lb); the results of the safety study indicate that there would be little to be concerned about and that there may be some black tarry stool. You should visit your Veterinarian to be on the safe side if you notice any symptoms and if you have activated charcoal, give it to them. An excerpt from the prescribing information is below along with a link the the document. Regards Dr Callum Turner DVM “In target animal safety studies, Rimadyl was administered orally to healthy Beagle dogs at 1, 3, and 5 mg/lb twice daily (1, 3 and 5 times the recommended total daily dose) for 42 consecutive days with no significant adverse reactions. Serum albumin for a single female dog receiving 5 mg/lb twice daily decreased to 2.1 g/dL after 2 weeks of treatment, returned to the pre-treatment value (2.6 g/dL) after 4 weeks of treatment, and was 2.3 g/dL at the final 6-week evaluation. Over the 6-week treatment period, black or bloody stools were observed in 1 dog (1 incident) treated with 1 mg/lb twice daily and in 1 dog (2 incidents) treated with 3 mg/lb twice daily. Redness of the colonic mucosa was observed in 1 male that received 3 mg/lb twice daily. Two of 8 dogs receiving 10 mg/lb orally twice daily (10 times the recommended total daily dose) for 14 days exhibited hypoalbuminemia. The mean albumin level in the dogs receiving this dose was lower (2.38 g/dL) than each of 2 placebo control groups (2.88 and 2.93 g/dL, respectively). Three incidents of black or bloody stool were observed in 1 dog. Five of 8 dogs exhibited reddened areas of duodenal mucosa on gross pathologic examination. Histologic examination of these areas revealed no evidence of ulceration, but did show minimal congestion of the lamina propria in 2 of the 5 dogs. In separate safety studies lasting 13 and 52 weeks, respectively, dogs were administered orally up to 11.4 mg/lb/day (5.7 times the recommended total daily dose of 2 mg/lb) of carprofen. In both studies, the drug was well tolerated clinically by all of the animals. No gross or histologic changes were seen in any of the treated animals.” www.fda.gov/downloads/AnimalVeterinary/Products/ApprovedAnimalDrugProducts/DrugLabels/UCM050406.pdf (see under animal safety)

This is a very similar situation to ours, very helpful answer ! I am very thankful I found this website

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Artoo
Australian Cattle
6 Years
Fair condition
0 found helpful
Fair condition

Has Symptoms

Lethargy

I gave my 38 lb blue heeler a 75mg carprofen last night as prescribed at 7:30pm. As all his other pills are to be taken every 12 hours, I gave him another one this morning at 8 am. I realized after that he should only get one every 24 hours. Is this something I should be concerned about? I'm worndering if this warrants a vet visit or just to keep a close eye on him and only give it every 24 hours from now on.

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
That one time dosage should not cause any toxic effects if Artoo is otherwise in good health. In the short term, it would be best to monitor him for any signs of vomiting, diarrhea, inappetance, or lethargy, and have him seen if he is having any of these problems. Otherwise, he should be able to get the next appropriate dosage 24 hours after the last dose.

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Charlie
French Bulldog
4 Months
Fair condition
1 found helpful
Fair condition

Has Symptoms

none

Hello, I was giving my dog her medication when my 4 month old Frenchie came and I was unable to tell who took ate the tablet. This happened at 6:45pm and it is now 7:45pm. So far no side symptoms have been seen. I’m not sure what the time frame would be for him to display symptoms. It was 50 mg of Carprofen. He weighs 16 lbs. He ate this on a full stomach and is not taking any other medications.

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Charlie received a dose of around 3.125mg/lb which is less than double therapeutic maximum dosage, we generally see symptoms after a single administration of five times or more of normal maximum dose. I would keep an eye on Charlie for the time being and ensure that he is hydrated; if any symptoms present you should visit your Veterinarian. Regards Dr Callum Turner DVM www.petpoisoncontrol.com/portfolio/carprofen/ http://veterinarymedicine.dvm360.com/toxicology-brief-managing-acute-carprofen-toxicosis-dogs-and-cats

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Annabelle
Collie
6 Years
Critical condition
0 found helpful
Critical condition

Has Symptoms

Seizures

Our 80lb rough collie ate a full bottle (60 tablets, brand new bottle) of 75mg Rimadyl. We know exactly how long she could have eaten them, max was 115 minutes between the time she was administered Apomorphine and vomiting was induced. She was transferred to an ICU within 3 hours of initial ingestion. They continued with the activated charcoal protocol, and administered an iv fluids program to flush her kidneys and help get the liver cleaned up from the charcoal (or thats my understanding anyway). At approximately 24 hours after the initial entry to the ICU, she started having full body tremors. I believe at that point, the ICU staff attributed it to excess sodium. As the day rolled into the next day, the tremors stopped but they were still measuring extremely high sodium levels. BUN and Creatinine were very high. By Day 3, BUN and Creatinine and the liver enzymes were all down to normal, but the small seizures still happened. We're on day 5 at this point. We know her brain is the only hold-out now, but what I'm trying to understand is how high sodium levels can cause full body tremors - I suspect the tremors were not just tremors but were also seizures. Can you explain why sodium levels would be elevated enough to trigger brain damage? We think at this point, she's probably not going to pull through enough to regain any degree of mobility or cognitive function. Annabelle is 6 years old and was in excellent health prior to this issue.

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
Thank you for your email. I'm so sorry that that happened to Annabelle, and to you. That is a very tragic accident. Extremely high sodium levels can decrease physiologic levels of fluid to the organs, including the brain, as the salt draws water to the bloodstream and away from the tissues. It essentially dehydrates the brain, and unless enough IV fluid therapy can be given to provide those cells with essential fluid, they will die. With acute kidney failure, the profound increase in urination as the kidneys lose control can cause that dramatic increase in sodium. I am sending all possible hope to you that she will recover this devastating event.

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Poppy
Labrador Retriever
11 Years
Moderate condition
0 found helpful
Moderate condition

Has Symptoms

Blood In Urine

Medication Used

Carprofen

My dog was prescribed carprofen and now has blood in her urine, and urinating more frequently. I am stopping the medication is there something else I can do. Otherwise she seems fine

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
Thank you for your email. Blood in the urine is one uncommon side effect of carprofen, so it is good that you stopped it. Other side effects include stomach or intestinal ulcers, so it would be a good idea to watch for any vomiting or diarrhea. If she was prescribed that medication for a painful condition, she may need an alternative drug to help her with that, and I would keep in mind that blood in the urine is a less common side effect, so may be unrelated to the drug, and monitor her for continued frequent urination or blood, as she may have a urinary problem. If she does vomit, have diarrhea, or continue to have frequent or bloody urination, she should have a recheck with her veterinarian.

I just reasantlylost my pit he was givin deramax for his bad hip. Then we ran out he was in discomfort over christmas so called emergancy clinic told them we were iut of deramax. They said its ok we will give you carprofen give it to him every 12 hrs 75mg rusting in them we did. Mean while we ordered deamax from heartland vets it got list in mail. All of a sudden my best friend was not eatting very lethargic white gums and blowted stomic with in 6 days new years day i took him to emg clinic were i was told he was bleed ing to the spleen . And removing it was coastly and not much of a survival rate blood trans 20 per chance needless to say my baby was bleeding to death. All they could say was it was a coincidence when i looked up mixing deramax followered by carprofen with no brake in between there a great side effects there should be at least 10 days well you beleave in your vets and i was never told this at all. Full worning do not us eaither. Phizer drug reps should inform vets more on this
I lost a part of my family and all they can say is im sorry for your loss instead of blaming the drug and giving to him with out imforming me.

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Duke
Bassett Hound
7 Years
Moderate condition
0 found helpful
Moderate condition

Has Symptoms

listlessness

Hello, I have an 88pound Bassett Hound Duke. Well Duke just had surgery where he had 2 separate masses removed. He was given 100mg Carprofen. Once daily. This evening between myself and my husband he accidentally was given 3 pills instead of one. Will he be okay?

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
Thank you for your email. The high dosage of Carprofen in dogs is 2 mg/ kg, or 80 mg once a day. Given that Duke received 3-4 times his recommended dosage of Carprofen, it would be best to have him seen by your veterinarian in the morning, to check some lab work, decide if he needs IV fluids for kidney function, or stomach protectants for his GI tract. I hope that he is okay.

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Simba
Labrador Retriever
11 Months
Fair condition
0 found helpful
Fair condition

Has Symptoms

Diarrhea
Vomiting

Medication Used

Truprofen

My 1 year old, 60lbs Lab was prescribed 50mg of Truprofen. We gave him 1 dose yesterday (Friday) night, and within 30 minutes he was throwing up. We found most of the pill in the vomit, but since then he's continued vomiting and had diarrhea. He seemed to be doing better this morning and was moving around fine and playing with his red ball, so we cautiously fed him ~1 cup of food at noon. About 2 hours later he threw that up, and parts of it were pink. We're not sure if it's blood or if it was from something else he ate. It's now 5pm on Saturday and the vet is closed. Is there anything at this point we can do? Is it late enough that activated carbon wouldn't help?

Dr. Michele King, DVM
Dr. Michele King, DVM
1607 Recommendations
Thank you for your email. Vomiting and diarrhea are an occasional side effect of Carprofen. If your veterinarian is closed, and he seems bright and happy at this point, a 12 hour fast sometimes helps settle their stomachs after something like this happens. If you feed him after 12 hours and he continues to vomit or have diarrhea, or he is becoming more lethargic or isn't interested in food, he should be seen as soon as possible to be evaluated and possibly given a medication to settle his intestinal tract down. I hope that everything goes well for Simba.

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Bronco
Mutt
4 Years
Fair condition
0 found helpful
Fair condition

Has Symptoms

Breathing Difficulties

Medication Used

Carprofen

I my dog was prescribed 5 tablets of carprophen and my other dog jumped on the counter and ate the remamining 3 while I was at work. He's not acting any differently for the past few hours. Will he be ok?

Dr. Callum Turner, DVM
Dr. Callum Turner, DVM
3317 Recommendations
Without knowing the dose of each tablet or Bronco’s weight I cannot say for certain that there will not be any problems, but you should call your Veterinarian to get another course of carprofen and discuss Bronco. Mainly vomiting and diarrhoea are the most common symptoms but without more information I cannot give further advice. Regards Dr Callum Turner DVM www.petpoisonhelpline.com/poison/carprofen/

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