Leukoencephalomyelopathy in Dogs

Leukoencephalomyelopathy is the term for spinal cord degeneration. This disease affects the white matter in the brain and spinal cord, causing loss of bodily control, muscle weakness, abnormal body movements, and inability to judge distance or scale.

There’s no definite cause for leukoencephalomyelopathy, though genetics seem to have a hand in determining which dogs are affected. This disease is most common in Rottweilers though other dogs have been known to have similar diseases. While some attempts at treatment have been done, most have been unsuccessful and end in having the dog put down.

Leukoencephalomyelopathy is a disease of the white matter in the brain and spinal cord, primarily in Rottweiler dogs. Other dogs known to be affected by similar diseases include Afghan Hounds, West Highland white terriers, miniature Poodles, Dalmatians, Jack Russell terriers, and fox terriers.

• Loss of control of bodily movements
• Inability to judge distance or scale
• Muscle weakness, typically affecting all four limbs
• Abnormal body positions or movements
• Hypermetria, in which a cerebellar dysfunction allows body parts to move beyond their intended reach
• Exaggerated spinal reflexes

Types

Because leukonecephalomyelopathy is a specific type of spinal cord disease, there aren’t exactly types of the disease itself. However, the way the disease affects the limbs of the dog can be categorized in two ways:

• Spastic, in which the dog’s lack of control over the limbs results in muscles spasms, contributing to other symptoms
• Flaccid, in which the dog’s lack of control over the limbs results in the limb hanging limply, again contributing to some of the other symptoms described

There really aren’t any known treatments that are effective for recovery. Some of the below treatments have been tried, but most cases end in euthanasia.

• Corticosteroid administration: Corticosteroids are steroid hormones produced in the adrenal cortex of vertebrates.
• Physical therapy may help in maintaining muscle strength, but will not cure the disease
• Hydrotherapy, the use of an exercise pool, may also help with muscle strength, but will not cure the disease