Dysbiosis (Leaky Gut Syndrome) Average Cost

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What is Dysbiosis (Leaky Gut Syndrome) ?

Dysbiosis is a change in the flora of the intestinal tract of your horse. This can be caused by something as simple as stress. If your horse is receiving medications such as antibiotics, this can cause changes to the natural flora as well. Either way, your horse will need supportive therapies in order to get the flora back in balance. A change in diet, ensuring he remains hydrated, and giving him probiotics will all be needed for the recovery process. If you do not treat your horse, it can lead to more serious conditions including insulin related issues, founders, laminitis, and other serious issues. If you begin treatment promptly, your horse has a good prognosis of recovery. However, if you do not treat him, he will only get worse and may develop secondary issues that may lead to his death.

Dysbiosis in horses, also known as leaky gut syndrome, all begins with a change in the gastrointestinal flora. It may start out minor, but if you let it go untreated, it can lead to serious illnesses or conditions developing in your horse.

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Symptoms of Dysbiosis (Leaky Gut Syndrome) in Horses

Symptoms of dysbiosis may vary from case to case but can include:

  • Stiffness and joint soreness
  • Fever
  • Fatigue
  • Poor exercise tolerance
  • Hyperactivity
  • Shortness of breath 
  • Mood swings
  • Irritable bowel syndrome
  • Inflammatory bowel disease
  • Bowel related bacterial infections


Dysbiosis is a result of the horse’s normal intestinal flora becoming imbalanced. This can occur after your horse has been on antibiotics and disturbed the normal flora. This can occur naturally due to your horse becoming ill, or it can happen after medications are administered which causes the intestinal flora to change.

Causes of Dysbiosis (Leaky Gut Syndrome) in Horses

When on antibiotics, it not only kills the bad bacteria in the gastrointestinal system but the good bacteria as well. This causes dysbiosis, or changes in the normal intestinal flora, and can lead to other digestive issues. Another cause could be hindgut acidosis; it leads to a change in the intestinal pH. This also leads to dysbiosis. Other medical issues that affect the gastrointestinal system can also play a potential role in causing dysbiosis.

Diagnosis of Dysbiosis (Leaky Gut Syndrome) in Horses

When diagnosing dysbiosis in horses, a fecal sample will be taken in order to see what microorganisms are present. In cases of dysbiosis, there is a reduced diversity of organisms in the feces. 

Symptoms will also help with diagnosis of dysbiosis. Many times, horses will develop dysbiosis without colitis; this can mean your horse will not have an appetite, but will be without any other symptoms. In other situations, the lack of good bacteria in the digestive tract can lead to poor absorption of nutrients from his diet. This can lead to loose or runny manure. 

Your veterinarian may also want to run blood work to check for other abnormalities your horse may be experiencing. A complete blood count and chemistry panel will give the veterinarian the needed information to determine if your horse is suffering from an additional illness or parasite in addition to the gut flora being abnormal.

Treatment of Dysbiosis (Leaky Gut Syndrome) in Horses

Treatment for dysbiosis can include multiple steps. Probiotic supplements offer the horse beneficial bacteria to replace the good bacteria that were lost. Prebiotics are another form of good bacteria that can be administered. Supplementing his diet with yeast is also thought to be beneficial. It aids in digestion and can be offered with a low risk of dysbiosis developing. 

Ensuring your horse stays hydrated and eating is also important during this time. Since nutrients are not being absorbed correctly, it can lead to malnutrition. Also, there may be excess fluid loss since absorption is being interfered with. Ensuring he stays hydrated with fluid therapy with added electrolytes is imperative. 

Changing your horse’s diet to something more appropriate for his condition is extremely important for recovery. Depending on what flora your horse is lacking and other symptoms he may be experiencing will determine the best type of food for him. There are specific diets you can purchase for horses suffering from dysbiosis; consult with your veterinarian in order to pick out the best one for your horse.

Recovery of Dysbiosis (Leaky Gut Syndrome) in Horses

If you do not take corrective measures to help your horse, dysbiosis can lead to more serious problems and possibly even a need to euthanize. If your horse has to go on antibiotics for any reason, put him on a probiotic at the same time in order to try and prevent abnormalities of the intestinal flora from developing. 

As soon as you notice your horse acting abnormally or his manure changes, call your veterinarian as soon as possible. The sooner you start treatment, the higher his prognosis of a full recovery with few or no lasting side effects.

Dysbiosis (Leaky Gut Syndrome) Questions and Advice from Veterinary Professionals

American Saddlebred
8 Years
Fair condition
0 found helpful
Fair condition

Has Symptoms

Watery stream down the right back l

My horse has had a stream down his bum from his anus ongoing for 3 weeks. I have deepened him and changed the hay. He has been placed on a prebiotic/ probiotic (slowly introducing it) for 4 days but no improvement. Most of the manure is firm but he does get the odd watery one. He has had this problem on and off since I've had him for 4 years .. was treated for ulcers in January and given the all clear after treatment with ulcer shield. I am wondering if this is dysbiosis?

Dr. Michele King, DVM
Dr. Michele King, DVM
1611 Recommendations
It is possible that Roo has dysbiosis, as this is a common problem after antibiotic therapy and can happen from an overgrowth of inappropriate bacteria. If his problem is not resolving, it would be best to have your veteriarian look at him, and see what mght be done to help him.

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Paint-draft cross
26 Years
Moderate condition
0 found helpful
Moderate condition

Has Symptoms

Loosing weight, loose stools

Our oldest horse(approx 26 y/o) has been loosing weight over the past year and has loose runny stools. We have been feeding him extra feed(Triple Crown Sr), flax seed, alfalfa cubes, and he has access to hay. I fear he has leaky gut syndrome-he is wasting away. He looks like he's being starved to death. What type of feed do you recommend and what brand(s)? He was on Phenobarb for 5+ years for seizures but our vet discontinued that last summer. He is on no RX meds at this time. (We also put Aloe vera juice in his feed-our vet said it helps some horses with keeping their weight).our e-mail is: [email protected] (Please note there is NO "h" in "cris" in our e-mail address).
Thank you.
Crystal and Jim Porter
P.S: he loves to eat-he has not lost his appetite!

Dr. Michele King, DVM
Dr. Michele King, DVM
1611 Recommendations
I'm glad that General still enjoys eating, that is a big deal! Without knowing more about him, I can't really comment on what type of feed might benefit him, but it would be worth discussing with your veterinarian, as they will have recommendations for him.

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